Dothee 50 Tablet
Prescription Required
View available alternative with same salt composition
Product introduction
Dothee 50 Tablet is a tricyclic antidepressant. It is mostly used to treat depression that is unresponsive to alternative treatment. It is also used in the management of anxiety disorders. It works by increasing the levels of chemical messengers in the brain that help in regulating the mood.
Dothee 50 Tablet works by increasing the levels of chemical messengers in the brain that stabilize and improve the mood. It is better to take it before bedtime because it can make you feel drowsy. It can be taken with or without food, but you should take it at a fixed time each day for better efficacy. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. Do not skip any dose and finish the full course of treatment even if you feel better. This medication must not be stopped suddenly without talking to the doctor. Your dose may be modified or gradually decreased before stopping the medication.
The most common side effects of Dothee 50 Tablet include increased heart rate, blurred vision, dryness in the mouth, and constipation. Initially, this medicine may also cause a sudden drop in blood pressure, especially when you change positions. It may even cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. It may also lead to weight gain in some people. Most of the common side effects tend to be mild and temporary. Your doctor may be able to suggest ways of preventing or reducing them. Serious side effects associated with this medicine are rare.
Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same or any other diseases. Pregnant and breastfeeding women should take this medicine with proper consultation and caution. This medicine is not known to be addictive, but you can experience additional side effects (withdrawal symptoms) if you stop taking it suddenly. If you notice any sudden mood change or suicidal or self-harm thoughts, you must consult a doctor without delay. Also, remember to take this medicine strictly as advised by the doctor, as an overdose of this medication may lead to a serious health emergency. Consumption of alcohol should be avoided as alcohol interacts with this medicine to cause serious health issues.
Uses of Dothee Tablet
Benefits of Dothee Tablet
In Treatment of Depression
Dothee 50 Tablet is used for the treatment of depression of any cause, including cases where anxiety is associated with depressive illness. It helps correct chemical imbalances in the brain linked to low mood and help reduce symptoms such as persistent sadness, anxiety, disturbed sleep, and loss of interest in daily activities. When used regularly as prescribed, it can support emotional stability, improve sleep and concentration, and help patients regain the ability to manage daily life and social functioning more effectively.
In Treatment of Anxiety disorder
Dothee 50 Tablet is thought to work by stopping your brain from releasing the chemicals that make you feel anxious, so it can reduce the symptoms of excessive anxiety and worry. It can also reduce feelings of restlessness, tiredness, difficulty concentrating, irritability, and sleep problems that often come with anxiety disorders. It will, therefore, help you go about your daily activities more easily and be more productive. Keep taking this medicine even if you feel well. Stopping suddenly can cause serious problems.
Side effects of Dothee Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Dothee
- Dryness in mouth
- Increased heart rate
- Orthostatic hypotension (sudden lowering of blood pressure on standing)
- Difficulty in urination
- Constipation
- Blurred vision
How to use Dothee Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dothee 50 Tablet may be taken with or without food.
How Dothee Tablet works
Dothee 50 Tablet works by increasing the levels of certain chemical messengers in the brain, mainly serotonin and noradrenaline, which are involved in regulating mood and emotional balance. It does this by reducing their reuptake into nerve cells, helping improve communication between brain cells, and relieving symptoms of depression.
Safety advice
Alcohol
UNSAFE
Do not drink alcohol while you are taking this medicine. Dothee 50 Tablet may cause excessive drowsiness when taken with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Dothee 50 Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding
CONSULT YOUR DOCTOR
Dothee 50 Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving
UNSAFE
Dothee 50 Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Dothee 50 Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver
CAUTION
Dothee 50 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
What if you forget to take Dothee Tablet?
If you miss a dose of Dothee 50 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Dothee 50 Tablet
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Quick tips
- Dothee 50 Tablet may take 4 to 6 weeks for Dothee 50 Tablet to start working. Keep taking it as prescribed.
- It may cause sleepiness. Take it at bedtime and do not drive or do anything requiring concentration until you know how it affects you.
- Avoid consuming alcohol when taking Dothee 50 Tablet as it may cause excessive sleepiness.
- Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
Fact Box
Chemical Class
Dibenzothiepins
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Tricyclic Antidepressants (TCAs)
Interaction with drugs
Taking Dothee with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not consume Tranylcypromine with Dosulepin. If Tranylcypromine is essential, ensure a gap of at least 2 weeks after discontinuing Dosulepin. Please consult your doctor.
Do not consume Moclobemide with Dosulepin. If Moclobemide is essential, ensure a gap of at least 1 day after discontinuing Dosulepin. Please consult your doctor.
Concomitant use m
Do not consume Domperidone with Dosulepin.
Concomitant use may affect heart rhythm and can be fatal.
Careful consideration is advised if you have epilepsy. Watch out for symptoms of serotonin syndrome, such as sedation, respiratory impairment, tremors, fever, diarrhea, or agitatio
If concurrent use is essential, watch out for symptoms such as sleepiness, dry mouth, impaired voluntary movements, weight gain, constipation, muscle stiffness or tremors and consu
FAQs
What is Dothee 50 Tablet used for?
Dothee 50 Tablet is a medicine used to treat anxiety disorder and depression that is unresponsive to other alternative medicines. It is also used to relieve nerve pain and fibromyalgia. Dothee 50 Tablet should be taken only if prescribed by a doctor, exactly as directed.
Is Dothee 50 Tablet a muscle relaxant?
No. Dothee 50 Tablet is not a muscle relaxant. It is a tricyclic antidepressant (TCA) used in the treatment of depression, nerve pain, and anxiety disorder.
How to stop Dothee 50 Tablet?
If your doctor asks you to stop Dothee 50 Tablet, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly. Sudden discontinuation may cause aggression, anxiety, blurred vision, concentration impairment, constipation and crying spells.
Is overdosing on Dothee 50 Tablet be fatal?
Yes. Dothee 50 Tablet can be fatal (can cause death) in overdose. This is due to a life-threatening or dangerous side effect in overdose like hyperthermia, seizure, arrhythmia, tachycardia, orthostatic hypotension or sudden death. That's why it is generally not considered a first-line option for depression because of side effect profile.
Can I take Dothee 50 Tablet with diazepam?
It is better to avoid this combination. Diazepam is a sedative drug and Dothee 50 Tablet may cause sedation as a side effect too. Taking both of them together can increase drowsiness or sleepiness. Inform your doctor if you are taking diazepam.
Can Dothee 50 Tablet be used to treat insomnia with depression?
Yes. Dothee 50 Tablet may be used for the treatment of insomnia (too much arousal both at night and during the day) associated with depression. Because it can cause drowsiness or sedation as side effects, it is effective in treating insomnia associated with depression.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Stahl SM, editor. Dothiepin. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 205-10.
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:
- Dosulepin [Package Insert]. Debrecen, Hungary: TEVA Pharmaceutical Work Private Limited; 2021. [Accessed 25 Jul. 2024] (online) Available from:
- Dosulepin [New Zealand Data Sheet]. Auckland, New Zealand: Viatris Ltd.; 2021.
Marketer details
Name: Tweet India Pharmaceuticals Pvt Ltd
Address: first floor, heera plaza, sec-8, vikas nagar, lucknow, uttar pradesh 226022
Country of origin: India
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₹99.9
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MRP₹110.63 10% OFF
10.0 tablets in 1 strip
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Prothiaden 50 Tablet
strip of 15 tablets
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Dosulepin (50mg)