
Diltiact Gel
Written By Dr. Lipika Khurana, PGDHHM, BDS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 23 Jan 2026 | 10:15 AM (IST)
Diltiact Gel is used for the treatment of anal fissures (tear in the lining of the anus). It relaxes the smooth muscles around the anus and promotes blood flow to the lining of the anus. This way it helps wound healing and reduces the associated symptoms.
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General Information
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Product introduction
Diltiact Gel is for external use only. Clean and dry the affected area and gently apply it over the affected area. It is advised to use it in the dose and duration as advised by your doctor. Limit physical exercises, standing, and prolonged sitting while on medication.
The most common side effects are application site reactions (burning, irritation, itching, and redness), dizziness, rectal bleeding, and headache. There are other, rarer side effects, some of them serious. Ask your doctor and read the leaflet which comes with the medicine to make sure you are keeping safe.
Uses of Diltiact Rectal Gel
Benefits of Diltiact Rectal Gel
Treatment of Anal fissure
Diltiact Gel is used to relieve pain, irritation, or itching caused by anal fissures (tear in the lining of the anus). It relaxes the blood vessels, thereby decreasing the pressure in the anal tissues. Use it in the dose and duration advised by your doctor.
Diltiact Gel is used to relieve pain, irritation, or itching caused by anal fissures (tear in the lining of the anus). It relaxes the blood vessels, thereby decreasing the pressure in the anal tissues. Use it in the dose and duration advised by your doctor.
Side effects of Diltiact Rectal Gel
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Diltiact
- Lightheadedness
- Headache
- Application site reactions (burning, irritation, itching and redness)
- Dizziness
How to use Diltiact Rectal Gel
This medicine is for external use only. Use it in the dose and duration as advised by your doctor.
How Diltiact Rectal Gel works
Diltiact Gel works in anal fissure by blocking the action of calcium on blood vessels of anus. As a result, blood vessels are relaxed which allows fissure (tear) to heal and relieves pain.
All substitutes for Diltiact Gel
For information purposes only. Consult a doctor before taking any medicine.
Quick tips
- Apply Diltiact Gel with clean hands using a finger cot or applicator to avoid contamination and ensure proper dosing.
- Use this medicine after bowel movement and gentle cleansing, as this allows better absorption and reduces irritation.
- Tell your doctor if you feel dizzy or lightheaded, since this medicine can lower blood pressure in some people.
- Avoid using on open wounds or bleeding hemorrhoids, unless directed, as it may worsen local irritation or discomfort.
- Continue its application consistently even if symptoms improve, unless advised otherwise, as stopping Diltiact Gel early may delay healing of fissures.
Safety advice

Alcohol
No interaction found/established

Pregnancy
CONSULT YOUR DOCTOR
Diltiact Gel is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding
CAUTION
Diltiact Gel should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving
No interaction found/established

Kidney
CONSULT YOUR DOCTOR
There is limited data available on the use of Diltiact Gel in patients with kidney disease. Please consult your doctor.

Liver
CONSULT YOUR DOCTOR
There is limited data available on the use of Diltiact Gel in patients with liver disease.
Interaction with drugs
Taking Diltiact with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe
Lemborexant (Oral Route)
Do not consume Lemborexant with Diltiazem. Diltiazem may raise blood levels of Lemborexant.
Moderate
Bortezomib (Injection Route)
Your doctor may monitor blood pressure and adjust the dose, if required.
Mild
Acalabrutinib (Oral Route)
If concurrent use is essential, your doctor may monitor for Acalabrutinib side effects. Diltiazem may raise blood levels of Acalabrutinib.
Frequently asked questions
No, it does not cure fissures but Diltiact Gel reduces inflammation of mucous membrane and skin. It reduces irritation, alleviates pain and itching, thus providing relief from symptoms.
Fissures usually heal within a few weeks. But if they do not, this is because the oxygen supply, carried by the blood, to these fissures is poor which further slows down the healing process. As a result, these fissures fail to heal and continue to get worse. You should consult a doctor immediately if you have been facing issues for a duration longer than a few weeks.
You must take a fiber-rich diet such as vegetables, fresh fruits and whole grains if you have fissures. Drink plenty of water and avoid taking alcohol. This will help ensure that your stools are soft and easy to pass. You may also take laxatives or fiber supplements if you are facing issues with digestion. Your doctor will suggest ways to avoid constipation and thereby promote healing of fissures.
No, spicy foods do not cause fissures. But, they can irritate the fissures and worsen your symptoms. Therefore, it is advised to avoid spicy foods if you are facing issues with your fissures.
Follow your doctor’s instructions before using Diltiact Gel. Apply a small amount of the gel to the affected rectal area as directed. If this is to be used inside the rectum, attach the rectal applicator onto the tube. Insert the applicator gently and to full extent into the rectum. After that, gently squeeze the tube to deliver the medication while withdrawing it.
Fissures usually heal within a few weeks. But, if they persist for longer than 4 to 6 weeks, they are termed as chronic fissures. Please consult your doctor without any delay if you have been noticing fissures for longer than 4 weeks.
Be careful not to get Diltiact Gel into your eyes or mouth. If you happen to get it in your eyes, rinse off with plenty of water immediately and contact your doctor. You must not use Diltiact Gel if you are allergic to it or any of its ingredients. Tell your doctor if you notice any allergic reaction while using it for the first time. Also, inform your doctor if you are taking any medicines regularly to prevent any allergic reaction with other medicines. Do not cover the area being treated with Diltiact Gel with a bandage, as this may increase absorption of this medicine and increase the side effects. Do not use more than what is recommended to relieve your symptoms faster. Using more than what is advised will only increase the side effects. Let your doctor know if you are planning to conceive.
Fact Box
Chemical Class
Benzothiazepines
Habit Forming
No
Therapeutic Class
CARDIAC
Action Class
Nondihydropyridine Calcium Channel Blockers
References
- Sampson KJ, Kass RS. Anti-Arrhythmic Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 830-31.
- Hume JR, Grant AO. Agents Used in Cardiac Arrhythmias. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 244.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 410-11.
- Opie LH. Calcium Channel Blockers. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 78-81.
- Central Drugs Standard Control Organisation (CDSCO). Diltiazem. [Accessed 15 Mar. 2019] (online) Available from:
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Once A Day
47%
Twice A Day
33%
Thrice A Day
13%
Four Times A Day
4%
Alternate Day
3%
Anal fissure
65%
Others
35%
Excellent
56%
Poor
28%
Average
17%
No Side Effect
100%
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Name: Sun Pharmaceutical Industries Ltd
Address: Khasra No. 1335-1340,Near EPIP- I, Vill - Bhatoli Kalan ,Baddi, Solan, Himachal Pradesh, 173205 || Plot no 107/108,Namli block , Ranipool, East Sikkim 737135
Address: Khasra No. 1335-1340,Near EPIP- I, Vill - Bhatoli Kalan ,Baddi, Solan, Himachal Pradesh, 173205 || Plot no 107/108,Namli block , Ranipool, East Sikkim 737135
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