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Diltigesic Organogel
Diltiazem (2% w/w)
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Diltigesic Organogel is used for the treatment of anal fissures (tear in the lining of the anus). It relaxes the smooth muscles around the anus and promotes blood flow to the lining of the anus. This way it helps wound healing and reduces the associated symptoms.
Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 28 May 2026 | 05:07 PM (IST)
Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 28 May 2026 | 05:07 PM (IST)
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30 gm Rectal Gel
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General Information
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Product introduction
Diltigesic Organogel is for external use only. Clean and dry the affected area and gently apply it over the affected area. It is advised to use it in the dose and duration as advised by your doctor. Limit physical exercises, standing, and prolonged sitting while on medication.
The most common side effects are application site reactions (burning, irritation, itching, and redness), dizziness, rectal bleeding, and headache. There are other, rarer side effects, some of them serious. Ask your doctor and read the leaflet which comes with the medicine to make sure you are keeping safe.
Uses of Diltigesic Rectal Gel
Benefits of Diltigesic Rectal Gel
Treatment of Anal fissure
Diltigesic Organogel is used to relieve pain, irritation, or itching caused by anal fissures (tear in the lining of the anus). It relaxes the blood vessels, thereby decreasing the pressure in the anal tissues. Use it in the dose and duration advised by your doctor.
Diltigesic Organogel is used to relieve pain, irritation, or itching caused by anal fissures (tear in the lining of the anus). It relaxes the blood vessels, thereby decreasing the pressure in the anal tissues. Use it in the dose and duration advised by your doctor.
Side effects of Diltigesic Rectal Gel
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Diltigesic
- Lightheadedness
- Headache
- Application site reactions (burning, irritation, itching and redness)
- Dizziness
How to use Diltigesic Rectal Gel
This medicine is for external use only. Use it in the dose and duration as advised by your doctor.
How Diltigesic Rectal Gel works
Diltigesic Organogel works in anal fissure by blocking the action of calcium on blood vessels of anus. As a result, blood vessels are relaxed which allows fissure (tear) to heal and relieves pain.
All substitutes for Diltigesic Organogel
For information purposes only. Consult a doctor before taking any medicine.
Quick tips
- Apply Diltigesic Organogel with clean hands using a finger cot or applicator to avoid contamination and ensure proper dosing.
- Use this medicine after bowel movement and gentle cleansing, as this allows better absorption and reduces irritation.
- Tell your doctor if you feel dizzy or lightheaded, since this medicine can lower blood pressure in some people.
- Avoid using on open wounds or bleeding hemorrhoids, unless directed, as it may worsen local irritation or discomfort.
- Continue its application consistently even if symptoms improve, unless advised otherwise, as stopping Diltigesic Organogel early may delay healing of fissures.
Safety advice

Alcohol
No interaction found/established

Pregnancy
CONSULT YOUR DOCTOR
Diltigesic Organogel is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding
CAUTION
Diltigesic Organogel should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving
No interaction found/established

Kidney
CONSULT YOUR DOCTOR
There is limited data available on the use of Diltigesic Organogel in patients with kidney disease. Please consult your doctor.

Liver
CONSULT YOUR DOCTOR
There is limited data available on the use of Diltigesic Organogel in patients with liver disease.
Interaction with drugs
Taking Diltigesic with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe
Lemborexant (Oral Route)
Do not consume Lemborexant with Diltiazem. Diltiazem may raise blood levels of Lemborexant.
Moderate
Bortezomib (Injection Route)
Your doctor may monitor blood pressure and adjust the dose, if required.
Mild
Acalabrutinib (Oral Route)
If concurrent use is essential, your doctor may monitor for Acalabrutinib side effects. Diltiazem may raise blood levels of Acalabrutinib.
Frequently asked questions
No, it does not cure fissures but Diltigesic Organogel reduces inflammation of mucous membrane and skin. It reduces irritation, alleviates pain and itching, thus providing relief from symptoms.
Fissures usually heal within a few weeks. But if they do not, this is because the oxygen supply, carried by the blood, to these fissures is poor which further slows down the healing process. As a result, these fissures fail to heal and continue to get worse. You should consult a doctor immediately if you have been facing issues for a duration longer than a few weeks.
You must take a fiber-rich diet such as vegetables, fresh fruits and whole grains if you have fissures. Drink plenty of water and avoid taking alcohol. This will help ensure that your stools are soft and easy to pass. You may also take laxatives or fiber supplements if you are facing issues with digestion. Your doctor will suggest ways to avoid constipation and thereby promote healing of fissures.
No, spicy foods do not cause fissures. But, they can irritate the fissures and worsen your symptoms. Therefore, it is advised to avoid spicy foods if you are facing issues with your fissures.
Follow your doctor’s instructions before using Diltigesic Organogel. Apply a small amount of the gel to the affected rectal area as directed. If this is to be used inside the rectum, attach the rectal applicator onto the tube. Insert the applicator gently and to full extent into the rectum. After that, gently squeeze the tube to deliver the medication while withdrawing it.
Fissures usually heal within a few weeks. But, if they persist for longer than 4 to 6 weeks, they are termed as chronic fissures. Please consult your doctor without any delay if you have been noticing fissures for longer than 4 weeks.
Be careful not to get Diltigesic Organogel into your eyes or mouth. If you happen to get it in your eyes, rinse off with plenty of water immediately and contact your doctor. You must not use Diltigesic Organogel if you are allergic to it or any of its ingredients. Tell your doctor if you notice any allergic reaction while using it for the first time. Also, inform your doctor if you are taking any medicines regularly to prevent any allergic reaction with other medicines. Do not cover the area being treated with Diltigesic Organogel with a bandage, as this may increase absorption of this medicine and increase the side effects. Do not use more than what is recommended to relieve your symptoms faster. Using more than what is advised will only increase the side effects. Let your doctor know if you are planning to conceive.
Fact Box
Chemical Class
Benzothiazepines
Habit Forming
No
Therapeutic Class
CARDIAC
Action Class
Nondihydropyridine Calcium Channel Blockers
References
- Sampson KJ, Kass RS. Anti-Arrhythmic Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 830-31.
- Hume JR, Grant AO. Agents Used in Cardiac Arrhythmias. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 244.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 410-11.
- Opie LH. Calcium Channel Blockers. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 78-81.
- Central Drugs Standard Control Organisation (CDSCO). Diltiazem. [Accessed 15 Mar. 2019] (online) Available from:
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User feedback
Once A Day
100%
Others
50%
Anal fissure
44%
Hypertension (high blood pressure)
4%
Angina (heart-related chest pain)
2%
Poor
46%
Average
41%
Excellent
13%
No Side Effect
40%
Headache
20%
Nausea
10%
Cough
10%
Dizziness
10%
With or without food
43%
Empty stomach
43%
With food
14%
Average
48%
Expensive
38%
Not Expensive
14%
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Troikaa Pharmaceuticals Ltd.
Address: Commerce House - 1', Satya Marg, Bodakdev, Ahmedabad-380 054. Gujarat, India.
Address: Commerce House - 1', Satya Marg, Bodakdev, Ahmedabad-380 054. Gujarat, India.
Vendor Details
Country of origin: India
A licensed vendor partner from your nearest location will deliver Diltigesic Organogel. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
A licensed vendor partner from your nearest location will deliver Diltigesic Organogel. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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