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Procarbazine is used alone or in combination with other medications to treat certain types of Hodgkin’s disease (types of cancer that begin in a type of white blood cells that normally fights infection).

How it works

Procarbazine belongs to a group of medicines called antineoplastic alkylating agents. It works by inhibiting protein, RNA, and DNA synthesis, which helps to stop the growth of cancer cells in the body.

Common side effects

Nausea, Frequent urge to urinate, Joint pain, Changes in skin color, Constipation, Dry mouth, Hair loss, Headache, Insomnia, Loss of appetite, Muscle pain, Bone pain, Stomach pain, Vomiting


Expert advice

  • Inform your doctor if you are suffering from severe hepatic or kidney disease, any disorder of the heart or circulation, have a tumor on the adrenal gland, causing high blood pressure, epilepsy (fits) or had stroke.
  • Inform your doctor if you have severe leucopenia or thrombocytopenia from any cause.
  • Take precautions as Procarbazine may lower the ability of your body to fight infections making you susceptible to infections.
  • Do not drive or operate machinery as Procarbazine may cause drowsiness.
  • You may need to regularly check and monitor blood counts due to the possibility of bone-marrow suppression with Procarbazine therapy. 
  • Do not take any live vaccines during or within at least 6 months of treatment with Procarbazine.

Content on this page was last updated on 03 October, 2016, by Dr. Varun Gupta (MD Pharmacology)