Desrina 50 Tablet ER

Reviewed By Dr. Mekhala Chandra, MD, MBBS

Last updated on 23 Sep 2025 | 06:46 PM (IST)

Desrina 50 Tablet ER is a prescription medicine used in the treatment of depression. This medicine helps by increasing the level of chemical messengers (serotonin and noradrenaline) in the brain that have a calming effect on the brain and relaxes the nerves, thus treating your depression.

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₹104 MRP ₹113.448% off

Desrina 50 Tablet ER is currently sold out

Same composition alternative:

MDD XR 50 Tablet

₹320~~₹350.46~~

Available alternative from Abbott

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Desrina 50 Tablet ER

strip of 10 tablet er

₹104

~~₹113.44~~

Same composition

MDD XR 50 Tablet

strip of 15 tablet er

Desvenlafaxine (50mg)

by Abbott

₹320

₹18.13 per unit

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General Information

Contains

Desvenlafaxine (50mg)

Marketer

Arinna Lifescience Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Desrina 50 Tablet ER is taken by mouth with or without food. Take it at a fixed time each day to maintain consistent level of medicine in the blood. In case you have missed a dose, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to doctor as this may worsen your symptoms.

Some common side effects of this medicine includes nausea, vomiting, insomnia (difficulty in sleeping), and constipation. It may cause an increase in blood pressure, especially during the first month of treatment, monitor your blood pressure regularly. It may even cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. It is important to inform your doctor if you develop any unusual changes in mood as it may lead to suicidal thoughts.

Uses of Desrina Tablet ER

Depression

Benefits of Desrina Tablet ER

Depression
Depression is a mood disorder that affects emotional well-being, energy, and daily functioning. Desrina 50 Tablet ER is used to manage depression by helping to restore balance in brain chemicals that influence mood. It supports better emotional stability, reduces symptoms like sadness, and helps improve overall quality of life.

Side effects of Desrina Tablet ER

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Desrina

Anxiety
Constipation
Decreased appetite
Dizziness
Increased sweating
Insomnia (difficulty in sleeping)
Nausea
Sexual dysfunction
Vomiting

How to use Desrina Tablet ER

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Desrina 50 Tablet ER may be taken with or without food, but it is better to take it at a fixed time.

How Desrina Tablet ER works

Desrina 50 Tablet ER works by increasing the levels of chemical messengers (serotonin and noradrenaline), natural substances in the brain that help maintain mental balance.

All substitutes for Desrina 50 Tablet ER

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Desrina 50 Tablet ER helps in treating depression and anxiety.
It may take 2 to 4 weeks for Desrina 50 Tablet ER to start working. Keep taking it as prescribed.
It may cause dizziness and sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
Avoid consuming alcohol when taking Desrina 50 Tablet ER as it may cause excessive drowsiness and increase the risk of liver damage.
It may cause a sensation of restlessness, especially when you first start taking it. Inform your doctor if this happens to you.
Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
Do not stop taking the medication suddenly without talking to your doctor.

Safety advice

Alcohol

CAUTION

Caution is advised when consuming alcohol with Desrina 50 Tablet ER. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Desrina 50 Tablet ER may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Desrina 50 Tablet ER is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Desrina 50 Tablet ER may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Desrina 50 Tablet ER should be used with caution in patients with kidney disease. Dose adjustment of Desrina 50 Tablet ER may be needed. Please consult your doctor.

Liver

CAUTION

Desrina 50 Tablet ER should be used with caution in patients with liver disease. Dose adjustment of Desrina 50 Tablet ER may be needed. Please consult your doctor.

Interaction with drugs

Taking Desrina with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Moclobemide (Oral Route)

Do not consume Moclobemide with Desvenlafaxine. If Moclobemide is essential, ensure a gap of at least 1 week after discontinuing Desvenlafaxine. Please consult your doctor.

Life-threatening

Tranylcypromine (Oral Route)

Your doctor may monitor your potassium levels regularly.

Life-threatening

Selegiline (Oral Route)

Do not consume Selegiline with Desvenlafaxine. If Selegiline is essential, ensure a gap of at least 2 weeks after discontinuing Desvenlafaxine. Please consult your doctor.

Severe

Ziprasidone (Oral Route)

Watch out for symptoms such as tremors, fever, diarrhea or agitation and consult your doctor if you experience them. Your doctor may discontinue the medicines accordingly.

Severe

Amitriptyline (Oral Route)

Talk to your doctor if you notice any unusual symptoms. Your doctor may adjust the dose if required.

Frequently asked questions

How long does it take for Desrina 50 Tablet ER to work?

The symptoms of depression like change in appetite and sleep patterns may show improvement within 1-2 weeks of starting Desrina 50 Tablet ER. However, it may take about 5-6 weeks to see the full benefits of Desrina 50 Tablet ER.

Is Desrina 50 Tablet ER good for anxiety?

It has been shown to be effective in relieving symptoms of anxiety, though it is not approved for anxiety. It is used in anxiety disorders only when advised by the doctor.

What time of the day is best to take Desrina 50 Tablet ER?

Desrina 50 Tablet ER can be taken either in the morning or in the evening. For best results, take this medicine at the same time each day. This will also help you remember to take it.

Can Desrina 50 Tablet ER be cut?

Desrina 50 Tablet ER should be swallowed whole with water. It should not be cut, chewed, crushed or dissolved. Take it exactly as directed by your doctor.

How can Desrina 50 Tablet ER help treat depression?

Desrina 50 Tablet ER belongs to a class of medicines known as serotonin and norepinephrine reuptake inhibitors (SNRIs). Serotonin and norepinephrine are chemical messengers in the brain which help maintain mental balance. Desrina 50 Tablet ER works by increasing the levels of these two hormones in the brain.

Will I gain weight while taking Desrina 50 Tablet ER?

Weight gain may occur with Desrina 50 Tablet ER, though not in everyone. In case you notice weight gain after taking Desrina 50 Tablet ER, consult your doctor or a nutritionist. Take a low calorie food, including more vegetables and fruits in your diet and exercise regularly.

Will Desrina 50 Tablet ER affect my sex drive?

Taking Desrina 50 Tablet ER may cause a decrease in sexual desire and ability. It may also cause a delay in orgasm and ejaculation and sometimes ejaculation failure. Discuss with your doctor if you experience any of these symptoms while taking Desrina 50 Tablet ER.

Fact Box

Chemical Class

Cyclohexanols Derivative

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Serotonin Norepinephrine Reuptake Inhibitors (SNRIs)

References

Stahl SM, editor. Desvenlafaxine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 175-80.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 375-77.
Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Desvenlafaxine. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:
Desvenlafaxine [Prescribing Information]. Philadelphia, PA: Wyeth Pharmaceuticals LLC; 2021. [Accessed 19 Jun. 2023]. (online) Available from:
Desvenlafaxine Extended Release [Product Information Sheet]. Ahmedabad, Gujarat: Torrent Pharmaceuticals Ltd. 2014. [Accessed 20 Feb. 2024] (online) Available from: torrentian.com/pisheet/Upload/PI_Sheet/1536.pdf

User feedback

Patients taking Desrina 50 Tablet ER

Once A Day

72%

Twice A Day

28%

What are you using Desrina Tablet ER for?

Others

100%

How much was the improvement?

Excellent

100%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Arinna Lifescience Pvt Ltd
Address: A – 504, Shapath-4, B/S Hotel Crowne Plaza, Opp. Karnavati Club, S. G. Highway ,Ahmedabad 380 051 Gujarat

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Desrina 50 Tablet ER

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Desrina Tablet ER

Benefits of Desrina Tablet ER

Side effects of Desrina Tablet ER

How to use Desrina Tablet ER

How Desrina Tablet ER works

All substitutes for Desrina 50 Tablet ER

Ventab Dxt 50 Tablet ER

Nexvenla-OD 50 Tablet ER

Desveren 50 Tablet ER

Newven OD 50 Tablet ER

Zyven-OD 50 Tablet ER

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Moclobemide (Oral Route)

Tranylcypromine (Oral Route)

Selegiline (Oral Route)

Ziprasidone (Oral Route)

Amitriptyline (Oral Route)

Frequently asked questions

How long does it take for Desrina 50 Tablet ER to work?

Is Desrina 50 Tablet ER good for anxiety?

What time of the day is best to take Desrina 50 Tablet ER?

Can Desrina 50 Tablet ER be cut?

How can Desrina 50 Tablet ER help treat depression?

Will I gain weight while taking Desrina 50 Tablet ER?

Will Desrina 50 Tablet ER affect my sex drive?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

User feedback

Patients taking Desrina 50 Tablet ER

What are you using Desrina Tablet ER for?

How much was the improvement?

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

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