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comforA Capsule

Pentosan polysulfate sodium (100mg)

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comforA Capsule is used to treat bladder pain or discomfort associated with interstitial cystitis (painful bladder syndrome). It works by forming a protective layer on the bladder wall, preventing irritating substances in urine from causing further irritation and damage.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 Nov 2025 | 03:05 PM (IST)

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10 capsules

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General Information

Contains

Pentosan polysulfate sodium (100mg)

Marketer

Swati Spentose Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

comforA Capsule is advised to take it in a dose and duration as per prescription. It should be taken on an empty stomach at least an hour before having a meal. Swallow the medicine as a whole without crushing or chewing it. You should not stop taking the medicine without consulting the doctor, as it may lead to the worsening of your symptoms.

Some of the common side effects of this medicine include hair loss, diarrhea, nausea, rash, and headache. In rare cases, blurred vision or difficulty adjusting to low light may occur with long-term use. If any side effects become bothersome or do not go away, inform your doctor. Seek medical attention if you experience unusual bleeding, severe stomach pain, or significant vision changes.

Do not take comforA Capsule if you are allergic to it. Inform your doctor if you have bleeding disorders, liver disease, or eye problems. This medicine may increase bleeding risk and affect vision with long-term use, so regular check-ups are advised. If you are pregnant, breastfeeding, or planning surgery, consult your doctor before use.

Uses of comforA Capsule

Interstitial cystitis

Benefits of comforA Capsule

Interstitial cystitis
Interstitial cystitis (IC), also known as painful bladder syndrome, is a chronic condition that causes bladder pressure, bladder pain, and sometimes pelvic pain. It occurs when the protective lining of the bladder is damaged, leading to irritation and inflammation. comforA Capsule helps by forming a protective layer on the bladder wall, reducing irritation and inflammation. This relieves pain, improves bladder function, and reduces the urgency and frequency of urination, helping patients manage daily life more comfortably.

Side effects of comforA Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of comforA

Hair loss
Abdominal pain
Abnormal liver function
Rash
Diarrhea
Nausea
Liver dysfunction
Dizziness
Headache

How to use comforA Capsule

Take this medicine in the dose and duration as advised by your doctor. comforA Capsule is to be taken on an empty stomach.

How comforA Capsule works

comforA Capsule works by attaching to the bladder wall and forming a protective barrier. This helps prevent harmful substances in urine from irritating the bladder lining. Additionally, it has mild blood-thinning properties and may improve blood flow to the bladder, supporting healing and reducing inflammation.

All substitutes for comforA Capsule

For information purposes only. Consult a doctor before taking any medicine.

Cystopen Capsule

by Sun Pharmaceutical Industries Ltd

₹68.3/capsule

7% costlier

For-IC Capsule

by Cipla Ltd

₹84.9/capsule

33% costlier

Quick tips

Take it at least 1 hour before meals or 2 hours after meals.
Inform your doctor if you will be undergoing any surgery or are taking anticoagulants such as warfarin sodium, heparin, or high doses of aspirin, as comforA Capsule may increase the risk of bleeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with comforA Capsule. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of comforA Capsule during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CAUTION

comforA Capsule should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

CONSULT YOUR DOCTOR

It is not known whether comforA Capsule alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of comforA Capsule in patients with kidney disease. Please consult your doctor.

Liver

CAUTION

comforA Capsule should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking comforA with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Apixaban (Oral Route)

Do not consume Apixaban with Pentosan polysulfate sodium. If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Pentosan polysulfate sodium may increase the effect of Apixaban.

Moderate

Rivaroxaban (Oral Route)

Do not consume Rivaroxaban with Pentosan polysulfate sodium. If concurrent use is essential, watch out for bleeding and consult your doctor immediately. They may adjust the dose of Pentosan polysulfate sodium accordingly.

Moderate

Dabigatran Etexilate (Oral Route)

Do not consume Dabigatran Etexilate with Pentosan polysulfate sodium. If concurrent use is essential, please consult your doctor.

Moderate

Dasatinib (Oral Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Your doctor may change the treatment accordingly.

Moderate

Bevacizumab (Injection Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately.

Frequently asked questions

Is comforA Capsule a steroid?

No, comforA Capsule is not a steroid. It is used in the treatment of interstitial cystitis, which is also known as bladder pain syndrome. This condition can cause sores and small areas of bleeding on the inside of the bladder, leading to pain and a frequent urge to urinate.

Can the use of comforA Capsule increase the risk of bleeding?

Yes, comforA Capsule is a weak anticoagulant, and it may increase your risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding, or if you notice blood in your stool.

Who should be cautious while starting comforA Capsule?

Do not take this medication without consulting your doctor. Inform the doctor if you have any disease for which you are taking blood-thinning medications like warfarin, heparin, aspirin, etc. This is done because the use of comforA Capsule can increase the risk of bleeding. Also, pregnant women and patients with liver problems should remain cautious while using this medicine.

How should I take comforA Capsule?

comforA Capsule should be taken in the dose as advised by the doctor. Take the medicine whole at least 1 hour before meals or 2 hours after meals, with one glass of water.

Fact Box

Chemical Class

O- glycosyl compounds

Habit Forming

Therapeutic Class

UROLOGY

Action Class

Semi-synthetic glycosaminoglycan

Related lab tests

Urine Routine & Microscopy

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1087-88.
Pentosan polysulfate sodium. Raritan, New Jersey: Ortho Women’s Health & Urology; 1998. [Accessed 04 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:
Pentosan polysulfate sodium [Prescribing Information]. Titusville, New Jersey: Janssen Pharmaceuticals, Inc.; 2024. [Accessed 11 Mar. 2025] (online) Available from:

User feedback

Patients taking comforA Capsule

Thrice A Day

63%

Twice A Day

28%

Once A Day

10%

What are you using comforA Capsule for?

Interstitial cystitis

78%

Others

22%

How much was the improvement?

Poor

67%

Average

33%

What were the side-effects while using comforA Capsule?

No Side Effect

25%

Nausea

25%

Dizziness

25%

Sleeping for unusually long periods

25%

How do you take comforA Capsule?

Empty stomach

75%

With food

25%

Please rate comforA Capsule on price

Average

44%

Not Expensive

33%

Expensive

22%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Swati Spentose Pvt Ltd
Address: 114, Marine Chambers, 11 New Marine Lines, Mumbai - 400 020 INDIA

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver comforA Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

comforA Capsule

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of comforA Capsule

Benefits of comforA Capsule

Side effects of comforA Capsule

How to use comforA Capsule

How comforA Capsule works

All substitutes for comforA Capsule

Cystopen Capsule

For-IC Capsule

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Apixaban (Oral Route)

Rivaroxaban (Oral Route)

Dabigatran Etexilate (Oral Route)

Dasatinib (Oral Route)

Bevacizumab (Injection Route)

Frequently asked questions

Is comforA Capsule a steroid?

Can the use of comforA Capsule increase the risk of bleeding?

Who should be cautious while starting comforA Capsule?

How should I take comforA Capsule?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Urine Routine & Microscopy

References

User feedback

Patients taking comforA Capsule

What are you using comforA Capsule for?

How much was the improvement?

What were the side-effects while using comforA Capsule?

How do you take comforA Capsule?

Please rate comforA Capsule on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests