
Combigel 10% Gel
Written By Dr. Lipika Khurana, PGDHHM, BDS
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS
Last updated on 25 Nov 2025 | 03:05 PM (IST)
Combigel 10% Gel is a pain-relieving medicine. It is used to treat moderate to severe pain in many conditions such as rheumatic pain, muscular aches, pain from strains and sprains, backache, and muscle tenderness or stiffness.
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General Information
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Product introduction
Combigel 10% Gel is only meant for external use and should be used strictly as advised by your doctor. A thin layer of the medicine should be massaged into the affected areas with clean and dry hands. Avoid getting in contact with your eyes, nose, or mouth, and avoid applying it on wounded or damaged skin. In case of accidental contact with these areas, you should rinse it with cold water.
It is usually safe with little or no side effects. However, it may cause a burning sensation and skin irritation at the site of application in some people. These are usually temporary and resolve with time. If they do not get better with time or worsen, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
Before using the medicine, it is important to tell your doctor if you are using or have recently used any other medicines for the same condition or other diseases. To make sure the medicine is safe, pregnant and breastfeeding women should consult their doctor before using the medicine.
It is usually safe with little or no side effects. However, it may cause a burning sensation and skin irritation at the site of application in some people. These are usually temporary and resolve with time. If they do not get better with time or worsen, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
Before using the medicine, it is important to tell your doctor if you are using or have recently used any other medicines for the same condition or other diseases. To make sure the medicine is safe, pregnant and breastfeeding women should consult their doctor before using the medicine.
Uses of Combigel Gel
Benefits of Combigel Gel
Pain relief
Combigel 10% Gel is a common painkiller used to treat aches and pains. It blocks chemical messengers in the brain that tell us we have pain. It is effective in relieving pain caused by headache, migraine, nerve pain, toothache, sore throat, period (menstrual) pains, arthritis, and muscle aches. This medicine is very widely used and very rarely causes side effects if taken at the right dosage.
Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time.
Combigel 10% Gel is a common painkiller used to treat aches and pains. It blocks chemical messengers in the brain that tell us we have pain. It is effective in relieving pain caused by headache, migraine, nerve pain, toothache, sore throat, period (menstrual) pains, arthritis, and muscle aches. This medicine is very widely used and very rarely causes side effects if taken at the right dosage.
Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time.
Treatment of Fever
Combigel 10% Gel is also used to reduce a high temperature (fever). It works by blocking the release of certain chemical messengers that cause fever. It may be prescribed alone or in combination with another medicine. You should take it regularly as advised by your doctor.
Combigel 10% Gel is also used to reduce a high temperature (fever). It works by blocking the release of certain chemical messengers that cause fever. It may be prescribed alone or in combination with another medicine. You should take it regularly as advised by your doctor.
Side effects of Combigel Gel
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Combigel
- No common side effects seen
- Vomiting
- Nausea
- Dizziness
- Abdominal pain
- Constipation
- Flatulence
- Diarrhea
- Dyspepsia
- Headache
- Fatigue
- Rash
How to use Combigel Gel
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.
How Combigel Gel works
Combigel 10% Gel is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling).
Quick tips
- You have been prescribed Combigel 10% Gel to relieve pain and inflammation.
- Apply it as a thin layer over the affected area or as suggested by your doctor.
- Do not apply to broken, diseased, infected, inflamed or irritated skin, or to open wounds.
- Avoid getting it in the eyes, mouth or nose. Rinse with cold water if you accidentally get it in these areas.
- It may increase the risk of sunburn. Avoid exposing the treated area of skin to excessive sunlight.
- Inform your doctor if you notice itching, redness of the skin, and peeling of skin while using this medicine.
Safety advice

Alcohol
No interaction found/established

Pregnancy
CONSULT YOUR DOCTOR
The safety of Combigel 10% Gel during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding
SAFE IF PRESCRIBED
Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.

Driving
No interaction found/established

Kidney
No interaction found/established

Liver
No interaction found/established
Interaction with drugs
Taking Combigel with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate
Citalopram (Oral Route)
Inform your doctor if you notice any signs of bleeding (bruising, bleeding gums, blood in stool/vomit/urine).
Moderate
Escitalopram Oxalate (Oral Route)
Inform your doctor if you notice any signs of bleeding (bruising, bleeding gums, blood in stool/vomit/urine).
Moderate
Fluoxetine (Oral Route)
Inform your doctor if you notice any signs of bleeding (bruising, bleeding gums, blood in stool/vomit/urine).
Moderate
Fluvoxamine (Oral Route)
Inform your doctor if you notice any signs of bleeding (bruising, bleeding gums, blood in stool/vomit/urine).
Moderate
Paroxetine (Oral Route)
Inform your doctor if you notice any signs of bleeding (bruising, bleeding gums, blood in stool/vomit/urine).
Fact Box
Chemical Class
Phenylpropanoic acids
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
Action Class
NSAID's- Non-Selective COX 1&2 Inhibitors (propionic acid)
Related lab tests
References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 682-84.
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
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Name: Biodyne Remedies Pvt Ltd
Address: 6, Neelkanth, Plot No 9, Sector 3, Ghansoli, Rabale, Navi Mumbai - 400701, Navi Mumbai
Address: 6, Neelkanth, Plot No 9, Sector 3, Ghansoli, Rabale, Navi Mumbai - 400701, Navi Mumbai
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Country of origin: India
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