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    Information about Fluoxetine

    Fluoxetine uses

    Fluoxetine is used in the treatment of depression, obsessive-compulsive disorder, Panic disorder and Bulimia nervosa.

    How fluoxetine works

    Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It works by increasing the levels of serotonin, a chemical messenger in the brain. This improves mood and physical symptoms in depression and relieves symptoms of panic and obsessive disorders.

    Common side effects of fluoxetine

    Abnormal dreams, Anxiety, Depression, Diarrhea, Dryness in mouth, Ejaculation disorder, Erectile dysfunction, Indigestion, Influenza like syndrome, Insomnia (difficulty in sleeping), Loss of appetite, Low sexual desire, Nasal congestion, Nausea, Rash, Sleepiness, Sore throat, Sweating, Tremor, Weakness, Weight loss, Yawning
    Content Details
    Written By
    Dr. Swati Mishra
    Reviewed By
    Dr. Varun Gupta
    MD (Pharmacology), MBBS
    Last updated on:
    16 Jan 2020 | 05:47 PM (IST)
    Want to know more?
    Read Our Editorial Policy

    Available Medicine for Fluoxetine

    • ₹32 to ₹108
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      4 variant(s)
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    Expert advice for Fluoxetine

    • Take Fluoxetine in the morning since it can keep you awake if taken late at night.
    • It may cause anxiety and agitation when you first start taking it.
    • It may cause weight loss and decreased appetite.
    • Don't drive or do anything requiring concentration until you know how Fluoxetine affects you.
    • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
    • Inform your doctor if you experience decreased sex drive or difficulty having an orgasm.
    • The addiction/dependence potential of Fluoxetine is very less.
    • Do not stop taking the medication suddenly without doctor consultation as that may lead to agitation, anxiety, and dysphoria.

    Frequently asked questions for Fluoxetine


    Q. What is Fluoxetine? What is it used for?

    Fluoxetine is an antidepressant drug and belongs to the class of selective serotonin re−uptake inhibitors (SSRIs). In adults, this medicine is used to treat major depressive episodes, eating disorder (bulimia nervosa) and obsessive-compulsive disorder (OCD). In children and adolescents aged eight years and above, it is used to treat moderate to severe major depressive disorder. Consult a doctor if you think you are suffering from depression as the treatment should always be taken as advised by a doctor.

    Q. Does Fluoxetine cause sleepiness?

    Somnolence (sleepiness) is a common side effect associated with the use of Fluoxetine. However, Fluoxetine can also cause other sleep problems like insomnia (inability to sleep) and abnormal dreams. Talk to your doctor in case you experience sleep problems while taking Fluoxetine.

    Q. Does Fluoxetine cause weight gain?

    Fluoxetine does not cause weight gain, rather it causes weight loss, which is a common side effect seen with its use. Weight loss is usually proportional to baseline body weight. Please consult your doctor if you experience a change in weight while taking Fluoxetine.

    Q. Does Fluoxetine make you tired?

    Fluoxetine can make you feel tired. Fatigue (extreme tiredness) is a very common side effect of Fluoxetine. Please consult your doctor if you experience excessive tiredness while taking it as the dose may need to be changed.

    Q. Does Fluoxetine cause a headache?

    Headache is a very common side effect of Fluoxetine. Please consult your doctor if you experience excessive headache while taking Fluoxetine.

    Q. Does Fluoxetine cause nausea?

    Nausea is a very common side effect of Fluoxetine. Please consult your doctor if you experience excessive nausea while taking Fluoxetine.

    Q. How long can I take Fluoxetine for?

    You should take Fluoxetine only for the duration as advised by your doctor. You should not stop the medicine without consulting your doctor.

    Q. Can I take Fluoxetine with paracetamol?

    Fluoxetine can be taken with paracetamol, however, when taken together paracetamol can increase the antidepressant effect of Fluoxetine. Talk to your doctor before taking the two medicines as there could be other effects of using the two medicines together.

    Q. Can I take Fluoxetine with birth control pills?

    Fluoxetine can be taken with birth control pills. No drug-drug interactions have been reported between the two. However, this does not mean that interactions cannot occur. Please consult your doctor before taking the two medicines together.

    Q. Is Fluoxetine addictive?

    Fluoxetine is not addictive in nature. No habit forming potential has been seen with its use. Always follow your doctor's advice regarding the duration of its use.

    Q. Is Fluoxetine safe in pregnancy?

    There have been some reports showing an increased risk of birth defects affecting the heart in babies when the mother took Fluoxetine during the first few months of pregnancy. When taken during the last three months of pregnancy, it may increase the risk of a serious condition in babies, called persistent pulmonary hypertension of the new born (PPHN), making the baby breathe faster and appear bluish. These symptoms usually begin during the first 24 hours after the baby is born. So, it is advisable not to use Fluoxetine during pregnancy. If you are pregnant or you are planning to have a baby, ask your doctor for advice before taking this medicine.

    Content on this page was last updated on 16 January, 2020, by Dr. Varun Gupta (MD Pharmacology)