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MD Pharmacology, MBBS
Last updated
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Clora 25mg Tablet

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SALT COMPOSITION
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Store below 30°C

Product introduction

Clora 25mg Tablet is a medicine used in the treatment of obsessive compulsive disorders (OCD), phobic states (such as intense fears that interfere with daily life), and depression. It works by increasing the levels of serotonin, a natural chemical in the brain that affects mood and behavior.

Take Clora 25mg Tablet exactly as prescribed by your doctor. The dose is usually started low and increased gradually to reduce side effects. It may take a few weeks before you notice the full benefits, so it is important not to stop taking it suddenly, even if you feel better. For best results, take the medicine at the same time every day and try not to miss any doses.


Common side effects of Clora 25mg Tablet include dry mouth, constipation, dizziness, drowsiness, blurred vision, increased sweating, and changes in appetite or weight. These are often mild and may improve as your body gets used to the medicine. If you feel very drowsy, avoid driving or operating heavy machinery. If any of these side effects persist or worsen, inform your doctor promptly.


Clora 25mg Tablet should be used with caution in people with heart disease, seizure disorders, glaucoma, or difficulty passing urine. This medicine can increase the risk of suicidal thoughts in some people, especially young adults; therefore, close monitoring at the start of treatment is important.


Clora 25mg Tablet should not be taken together with medicines called monoamine oxidase inhibitors (MAOIs), or within two weeks of stopping them, due to the risk of serious reactions. Alcohol should be avoided as it can worsen drowsiness and other side effects. Pregnant and breastfeeding women should consult their doctors before taking this medicine to make sure it is safe.


Benefits of Clora Tablet

In Treatment of Depression

Clora 25mg Tablet helps lift mood, relieve feelings of sadness or hopelessness, and helps restore energy and interest in daily activities. It can also improve sleep and appetite, which are often disrupted during depression. Alleviating these symptoms enables the patients to reconnect with loved ones, engage in work or hobbies, and experience an overall improvement in their quality of life.

In Treatment of Obsessive-compulsive disorder

Clora 25mg Tablet helps reduce the intensity and frequency of obsessive thoughts and the urge to perform repetitive actions. This can give patients relief from time-consuming rituals and overwhelming anxiety, allowing them to regain control over daily life. When taken regularly in the dose and duration prescribed by the doctor, it can help patients focus better on work, studies, and relationships, leading to a more balanced and fulfilling lifestyle.

In Treatment of Phobia

For people struggling with persistent and intense fears (phobias), Clora 25mg Tablet can help ease anxiety and reduce avoidance behaviors. It enables patients to face situations that once felt impossible, such as traveling, social interactions, or going to public places, with greater confidence. Lowering fear responses allows them to participate more fully in everyday activities and regain independence.

Side effects of Clora Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Clora

  • Dryness in mouth
  • Constipation
  • Nausea
  • Indigestion
  • Decreased appetite
  • Sleepiness
  • Tremors
  • Dizziness
  • Nervousness
  • Myoclonus
  • Altered libido
  • Ejaculation disorder
  • Impotence
  • Micturition disorders
  • Fatigue
  • Increased sweating
  • Increased appetite
  • Weight gain
  • Altered vision

How to use Clora Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Clora 25mg Tablet is to be taken with food.

How Clora Tablet works

Clora 25mg Tablet works by increasing the activity of serotonin, a natural chemical messenger in the brain that influences mood, thoughts, and behavior. It blocks the reuptake of serotonin into nerve cells, which helps keep more of it available between brain cells. This action helps reduce obsessive thoughts, lessen compulsive behaviors, ease anxiety from phobias, and improve mood in depression.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Clora 25mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Clora 25mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Clora 25mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Clora 25mg Tablet may cause side effects which could affect your ability to drive.
If you feel dizzy, tired, have blurred vision, have difficulty concentrating, or have other effects such as confusion, disorientation or your depression gets worse with Clora 25mg Tablet, do not drive.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Clora 25mg Tablet in patients with kidney disease. Please consult your doctor.
Liver
CAUTION
Clora 25mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Clora 25mg Tablet may be needed. Please consult your doctor.
Regular monitoring of liver function tests is advisable when you are taking this medicine.

What if you forget to take Clora Tablet?

If you miss a dose of Clora 25mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Clora 25mg Tablet
₹3.89/Tablet
Clofranil 25mg Tablet
Sun Pharmaceutical Industries Ltd
₹6.27/tablet
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₹6.39/tablet
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CLOnil 25 Tablet
Intas Pharmaceuticals Ltd
₹6.38/tablet
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Arimip 25mg Tablet
Arinna Lifescience Pvt Ltd
₹6.23/tablet
60% costlier
Omifram 25 Tablet
Zeelab Pharmacy Pvt Ltd
₹1.48/tablet
62% cheaper

Quick tips

  • Take Clora 25mg Tablet at the same time every day to build a routine and avoid missed doses.
  • Do not stop the medicine suddenly, even if you feel better; always consult your doctor before making changes.
  • Avoid driving or operating heavy machines until you know how it affects you, as Clora 25mg Tablet may cause drowsiness.
  • Limit or avoid alcohol, as it can increase drowsiness and side effects.
  • Make sure to attend all follow-up visits with the doctor to monitor your dose and progress.

Fact Box

Chemical Class
Dibenzoxepin Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Tricyclic Antidepressants (TCAs)

Interaction with drugs

Taking Clora with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not consume Moclobemide with Clomipramine. If Moclobemide is essential, ensure a gap of at least 1 day after discontinuing Clomipramine. Please consult your doctor. Concomitant... More
Do not consume Escitalopram Oxalate with Clomipramine. Escitalopram Oxalate may raise blood levels of Clomipramine. Concomitant use may affect heart rhythm and may be fatal.
Do not consume Thioridazine with Clomipramine. Concurrent use may cause fatal disturbances in the heart rhythm.
Do not consume Amiodarone with Clomipramine. Concomitant use may affect heart rhythm and may be fatal.
Do not consume Ondansetron with Clomipramine. Concomitant use may affect heart rhythm and may be fatal.

Patient concerns

I have Obsessive compulsive Disorder. Prescribe the medication.
Dr. Deepak Kumar Soni
Ayurveda
Hi Kindly share your symptoms of your Problem
Sir, I wont to take best medicine of Ayurveda for obsessive compulsive disorders(Depression)
Dr. Ankur Kumar Tanwar
Ayurveda
Use brahmi granules and jatamansi vati ,

User feedback


FAQs

What is Clora 25mg Tablet and what does it treat?

Clora 25mg Tablet is a tricyclic antidepressant used to treat obsessive-compulsive disorder (OCD), phobic states, and depression (when sedation is helpful). It is often prescribed when obsessive thoughts, intense fears, or depressed mood interfere with daily life.

How long before I notice improvement?

Some people may notice early improvements in a few weeks, but meaningful benefit for OCD or depression often takes 6–12 weeks, and full effects can take longer. Steady drug levels may take 1–3 weeks after dose changes. Continue taking it for as long as prescribed and do not stop it suddenly.

How should I take it?

Take it exactly as your doctor prescribes. Treatment usually starts at a low dose and is increased gradually to reduce side effects. Take doses with meals if advised; this will help reduce upset stomach. Take it at the same time each day and ensure to attend all follow-up visits so your doctor can review your dose and response.

Are there any serious risks I should know about?

Yes. Clora 25mg Tablet may cause seizures, heart rhythm problems, and can increase suicidal thoughts in young people early in treatment. Do not use it with MAO inhibitors or within 14 days of stopping them due to the risk of life-threatening serotonin syndrome. Get urgent help for new suicidal thoughts, fainting, chest pain, severe heartbeat changes, or signs of serotonin syndrome like high fever, stiff muscles, or confusion.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Stahl SM, editor. Clomipramine. In: Stahl's Essential Psychopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 129-35.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 298-300.
  3. CDSCO: List of New Drugs Approved in India From 1991 to 2000. [Accessed 25 Sept. 2025] (online) Available from: External Link
  4. Clomipramine Hydrochloride [Prescribing Information]. Mumbai, India: Unique Pharmaceutical Laboratories; 2025. [Accessed 25 Sept. 2025] (online) Available from: External Link
  5. Clomipramine Hydrochloride [Prescribing Information]. Wellington, New Zealand: Arrotex Pharmaceuticals (NZ) Limited; 2024. [Accessed 25 Sept. 2025] (online) Available from: External Link
  6. Clomipramine hydrochloride [Drug Label]. Whitby, Ontario, Canada: Patheon Inc.; 2019. [Accessed 25 Sept. 2025] (online) Available from: External Link

Marketer details

Name: Sigmund Promedica
Address: 30-22-118, First Floor, Eluru Road,Seetharampuram,Vijayawada 520 002,Andhra Pradesh
Country of origin: India

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Inclusive of all taxes
MRP42.19  8% OFF
10.0 tablets in 1 strip
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