






Clopixol Depot Injection
Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 25 Nov 2025 | 03:05 PM (IST)

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General Information







Product introduction
Clopixol Depot Injection is given as an injection under the supervision of a healthcare professional and should not be self-administered. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. This medication mustn't be stopped suddenly without talking to your doctor as it may worsen your symptoms.
Some common side effects of this injection include dry mouth, abnormality of voluntary movements, urinary retention, constipation, and muscle rigidity. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, rise slowly if you have been sitting or lying down. It may also cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine can lead to weight gain, have a healthy balanced diet, and exercise regularly. You may also notice some injection site reactions such as pain, redness, or swelling. However, these are temporary and usually resolve on their own. Please consult your doctor in case these do not subside or bother you.
Before taking it, inform your doctor if you are suffering from thyroid or kidney problems, epilepsy, Parkinson’s disease, glaucoma, or any heart problems. You should not take this medicine if you are under the influence of alcohol or any sleep-inducing, cough, and/ or allergy medication. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly.
Uses of Clopixol Injection
Benefits of Clopixol Injection
Clopixol Depot Injection reduces the symptoms of excessive anxiety and worry. It can also reduce feelings of restlessness, tiredness, difficulty concentrating, and feeling irritable. It will therefore help you go about your daily activities more easily and be more productive.
Schizophrenia is a mental disorder in which a person’s thinking ability, feelings, and behavior become abnormal. Clopixol Depot Injection helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life.
Side effects of Clopixol Injection
- Abnormality of voluntary movements
- Constipation
- Dryness in mouth
- Increased prolactin level in blood
- Orthostatic hypotension (sudden lowering of blood pressure on standing)
- Sleepiness
- Tremors
- Urinary retention
- Weight gain
How to use Clopixol Injection
How Clopixol Injection works
Quick tips
- Clopixol Depot Injection is administered into the muscle of the buttock or thigh.
- Use caution while driving or doing anything that requires concentration as Clopixol Depot Injection can cause dizziness and sleepiness.
- Avoid drinking alcohol while taking this medicine because it can make drowsiness worse.
- It may affect how your body regulates your temperature. Avoid situations that can result in your overheating or getting dehydrated.
- It may increase your weight, blood sugar and cholesterol. Eat healthy, exercise regularly and monitor your blood levels regularly.
- Inform your doctor if you experience any swelling, particularly of the face, lips, jaw and tongue and trouble breathing while taking this medicine.
Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver
Interaction with drugs
Thioridazine (Oral Route)
Amiodarone (Oral Route)
Pimozide (Oral Route)
Haloperidol (Oral Route)
Fact Box
Chemical Class
Habit Forming
Therapeutic Class
Action Class
References
- Stahl SM, editor. Zuclopenthixol. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 769-73.
- Zuclopenthixol acetate. St Albans: Lundbeck Limited; 2008 [revised Dec 2016]. [Accesed 19 Mar. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Zuclopenthixol. [Updated 2018 Dec 3]. [Accessed 20 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:




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Address: Lundbeck India Private Limited, "H M Towers", I Floor, #58, Brigade Road, Kodihalli BDA, HAL II Stage, 560 025, Bangalore, India
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