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Cilamin 250 Capsule

Penicillamine (250mg)

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Cilamin 250 Capsule is used in the treatment of rheumatoid arthritis, Wilson's disease, and cystinuria. It slows the progression of rheumatoid arthritis and provides relief from pain and swelling in the joints. In the treatment of Wilson's disease, it helps to remove the excess copper from the body.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 26 Aug 2026 | 01:02 AM (IST)

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General Information

Contains

Penicillamine (250mg)

Marketer

Mankind Pharma Ltd

Storage

Store below 25°C

The content is shown in English

Product introduction

Cilamin 250 Capsule is to be taken on an empty stomach. You should take it regularly and at the same time each day to get maximum benefit from it. Keep taking it as recommended by your doctor and complete the dose even if you feel better.

Using this medicine may cause some common side effects such as rashes, nausea, vomiting, and diarrhea. Your doctor may recommend regular blood tests to check and make sure the medicine is not harming your liver or affecting your blood counts. You should consult with your doctor if any of these side effects do not resolve with time or get worse. Your doctor may help with ways to reduce or prevent these symptoms.

To make sure the medicine is safe for you, before taking this medicine, let your doctor know if you have any problems with your kidneys. Also, tell your doctor about all the other medicines you are taking. Pregnant and breastfeeding mothers should consult with their doctors before taking the medicine.

Uses of Cilamin Capsule

Treatment of Rheumatoid arthritis
Treatment of Wilson's disease

Benefits of Cilamin Capsule

Treatment of Rheumatoid arthritis
Rheumatoid arthritis is an autoimmune condition where the immune system attacks the joints, causing pain, swelling, and stiffness. Cilamin 250 Capsule is used to manage symptoms in patients who haven't responded well to other treatments. It can slow joint damage and improve mobility over time.

Treatment of Wilson's disease
Wilson's disease is a rare genetic disorder where excess copper builds up in the body, damaging organs like the liver and brain. Cilamin 250 Capsule helps by binding to the excess copper, allowing it to be safely removed from the body, which helps prevent organ damage and supports long-term health.

Side effects of Cilamin Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Cilamin

Vomiting
Nausea
Rash
Decreased appetite
Stomach pain
Abnormal taste
Protein in urine
Decreased white blood cell count (lymphocytes)
Low blood platelets

How to use Cilamin Capsule

Take this medicine in the dose and duration as advised by your doctor. Cilamin 250 Capsule is to be taken on an empty stomach.

How Cilamin Capsule works

Cilamin 250 Capsule works by blocking the action of certain chemical messengers that are responsible for inflammation and slows the progress of the condition with certain joint diseases. It works in Wilson's disease by helping the body to remove excess copper, and in cystinuria by preventing cystine stone formation through increased solubility.

All substitutes for Cilamin 250 Capsule

For information purposes only. Consult a doctor before taking any medicine.

Penicitin 250mg Capsule

by Samarth Life Sciences Pvt Ltd

₹15.7/capsule

3% costlier

Quick tips

Take Cilamin 250 Capsule on an empty stomach, at least 1 hour before or 2 hours after meals, for better absorption.
Avoid taking it with iron, antacids, or zinc supplements within 2 hours, as they may reduce its effectiveness.
Inform your doctor if you notice any signs of infection, bruising, or fatigue, as regular blood monitoring is essential.
Use effective contraception if you're of childbearing age, as Cilamin 250 Capsule may harm an unborn baby.
Stay hydrated and follow any dietary restrictions advised by your doctor to reduce the risk of side effects.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Cilamin 250 Capsule. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Cilamin 250 Capsule is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Cilamin 250 Capsule may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Taking Cilamin 250 Capsule right after nursing and waiting for 4 to 6 hours before nursing again will minimize the harmful effects to the baby.

Driving

UNSAFE

Cilamin 250 Capsule may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Cilamin 250 Capsule should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Cilamin 250 Capsule is not recommended in patients with severe kidney disease.

Liver

SAFE IF PRESCRIBED

Cilamin 250 Capsule is safe to use in patients with liver disease. No dose adjustment is recommended.

Interaction with drugs

Taking Cilamin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Leflunomide (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.

Severe

Teriflunomide (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.

Moderate

Clozapine (Oral Route)

Do not consume Clozapine with Penicillamine. If concurrent use is essential, your doctor may monitor your blood cell count frequently.

Moderate

Aceclofenac (Oral Route)

Do not consume Penicillamine with Aceclofenac. If concurrent use is essential, please consult your doctor.

Moderate

Aceclofenac (Injection Route)

Do not consume Penicillamine with Aceclofenac. If concurrent use is essential, please consult your doctor.

Frequently asked questions

What is Cilamin 250 Capsule used for?

Cilamin 250 Capsule is prescribed for several conditions, such as in Wilson's disease (excess copper in the body), severe rheumatoid arthritis, and certain types of kidney stones (cystinuria). Your doctor may also prescribe Cilamin 250 Capsule in case of heavy metal (lead) poisoning. Your doctor will determine if it is right for your specific condition.

What foods and supplements should I avoid?

You should avoid taking milk, antacids, zinc, or iron-containing supplements within 2 hours of taking Cilamin 250 Capsule. Additionally, avoid copper-rich foods if you have Wilson’s disease and other mineral supplements unless approved by your doctor.

What serious side effects should I watch for?

You should seek immediate medical attention during Cilamin 250 Capsule treatment if you experience serious side effects such as unusual bleeding or bruising, fever or sore throat, unusual tiredness, blood in urine, joint pain, swelling, severe breathing difficulty, rash, etc. These could indicate serious complications requiring prompt attention.

How long does it take to see results?

The exact time Cilamin 250 Capsule takes to show results is not known. The timeline for noticeable improvement varies by individual, condition, and its severity. The initial improvement in symptoms may take a few months. You should continue taking Cilamin 250 Capsule even if you feel better and follow your doctor’s instructions and restrictions.

Are there special precautions for pregnancy?

You should inform your doctor if pregnant or planning pregnancy, as this may require adjusting or changing treatment and regular monitoring during pregnancy. Cilamin 250 Capsule may be contraindicated in some cases. Discuss risks and benefits with your doctor.

Fact Box

Chemical Class

Valine derivative

Habit Forming

Therapeutic Class

BLOOD RELATED

Action Class

Non-Biologic DMARDs (Disease Modifying Anti-Rheumatoid Drugs)

Related lab tests

Rheumatoid Factor - Agglutination

Rheumatoid Factor - Turbidometry

Rheumatoid Factor IgG Antibody

References

Aminoff MJ. Pharmacologic Management of Parkinsonism & Other Movement Disorders. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 482.
Byrns MC, Penning TM. Environmental Toxicology: Carcinogens and Heavy Metals. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1875.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1079-80.
Penicillamine.Hunt Valley, USA: Pharmaceutics International, Inc.; 2018. [Accessed 02 Apr. 2019] (online) Available from:
Penicillamine [Package Insert]. Princeton, NJ: Dr. Reddy’s Laboratories Inc.; 2018. [Accessed 03 Aug. 2023] (online) Available from:

User feedback

Patients taking Cilamin 250 Capsule

Once A Day

60%

Twice A Week

20%

Thrice A Day

20%

What are you using Cilamin Capsule for?

Others

61%

Rheumatoid arthritis

39%

How much was the improvement?

Excellent

44%

Average

33%

Poor

23%

What were the side-effects while using Cilamin 250 Capsule?

No Side Effect

58%

Low blood platelets

25%

Protein in urine

17%

How do you take Cilamin Capsule?

Empty stomach

53%

With food

40%

With or without food

Please rate Cilamin 250 Capsule on price

Average

40%

Expensive

37%

Not Expensive

23%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Mankind Pharma Ltd
Address: 208, Okhla Industrial Estate, Phase III, New Delhi - 110020

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Cilamin 250 Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Home

Blood Related

Chelating Agents

Cilamin 250 Capsule

Cilamin 250 Capsule

Cash on delivery

Free Return

Expiry after

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Cilamin Capsule

Benefits of Cilamin Capsule

Side effects of Cilamin Capsule

How to use Cilamin Capsule

How Cilamin Capsule works

All substitutes for Cilamin 250 Capsule

Penicitin 250mg Capsule

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Leflunomide (Oral Route)

Teriflunomide (Oral Route)

Clozapine (Oral Route)

Aceclofenac (Oral Route)

Aceclofenac (Injection Route)

Frequently asked questions

What is Cilamin 250 Capsule used for?

What foods and supplements should I avoid?

What serious side effects should I watch for?

How long does it take to see results?

Are there special precautions for pregnancy?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Rheumatoid Factor - Agglutination

Rheumatoid Factor - Turbidometry

Rheumatoid Factor IgG Antibody

References

User feedback

Patients taking Cilamin 250 Capsule

What are you using Cilamin Capsule for?

How much was the improvement?

What were the side-effects while using Cilamin 250 Capsule?

How do you take Cilamin Capsule?

Please rate Cilamin 250 Capsule on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests