Leflunomide

Yes, Leflunomide may cause weight loss as a common side effect. However, weight loss due to this medicine is usually insignificant. The reason for this reduction in weight could be due to accompanying loss of appetite. Consult your doctor if your weight loss is significant.

Leflunomide belongs to disease-modifying antirheumatic drugs (DMARDs) class of medicines. It works by reducing inflammation and slowing the progress of the disease. This medicine can help patients with rheumatoid arthritis by improving their physical activity.

Although not very common but Leflunomide may cause serious side effects. These may include liver damage, severe infections, serious skin reactions, blood cell deficiency, numbness and pain in hands and feet, and lung disease (interstitial lung disease). If you have any doubts, discuss with your doctor before starting treatment.

You should avoid alcohol while on treatment with Leflunomide. This is because using them together may cause liver toxicity.

Your doctor will carry regular tests before and during treatment with Leflunomide to check your blood cells and liver function. Along with that, your doctor will check your blood pressure regularly as Leflunomide can cause an increase in blood pressure.

The doctor should be informed if one has lung problems like cough, shortness of breath or if one observes symptoms of infection like fever, weakens, and flu-like symptoms. Along with that, if a person experiences allergic reactions like hives rashes and liver problems like yellowing of skin, loss of appetite then it should be consulted with the doctor. One should also inform the doctor if there is a decrease in blood cell count causing easy bruising and recurrent infections. In addition to that, the doctor should be informed if one becomes pregnant during the course of treatment.

Leflunomide takes fairly long time to get flushed out of your system. Hence, you should not plan pregnancy for at least 2 years after stopping Leflunomide. This extensive time duration may be reduced to a few weeks by taking certain medicines which can help speed up the removal of Leflunomide from your body.

Leflunomide may take about 4 weeks or longer to show improvement in the condition. It may even take 4-6 months to show full benefits. Hence, the medicine should not be stopped if there is no significant improvement. For any further query consult your doctor who will analyze the condition.

Leflunomide may increase your chances of cancer especially of lymph system, but this is very rare. The reason could be decreased strength of the immune system caused by Leflunomide. Discuss with your doctor if you have concerns regarding it.