Information about Leflunomide

    Leflunomide uses

    Leflunomide is used in the treatment of rheumatoid arthritis and psoriatic arthritis.

    How leflunomide works

    Leflunomide blocks the action of certain chemical messengers that are responsible for inflammation, swelling and redness associated with certain autoimmune diseases. It suppresses the underlying disease process, rather than simply treating the disease.

    Common side effects of leflunomide

    Nausea, Headache, Dyspepsia, Rash, Diarrhoea, Increased liver enzymes, Respiratory tract infection

    Available Medicine for Leflunomide

    • ₹98 to ₹199
      Ipca Laboratories Ltd
      3 variant(s)
    • ₹120 to ₹199
      Torrent Pharmaceuticals Ltd
      2 variant(s)
    • ₹177 to ₹444
      Zydus Cadila
      3 variant(s)
    • ₹292 to ₹572
      Sanofi India Ltd
      2 variant(s)
    • ₹108 to ₹195
      Cipla Ltd
      2 variant(s)
    • ₹101 to ₹191
      Sun Pharmaceutical Industries Ltd
      2 variant(s)
    • ₹96
      Wallace Pharmaceuticals Pvt Ltd
      1 variant(s)
    • ₹89 to ₹170
      Ronyd Healthcare Pvt Ltd
      2 variant(s)
    • ₹194
      Ronyd Healthcare Pvt Ltd
      1 variant(s)
    • ₹240
      Rhumasafe Pharmaceutical
      1 variant(s)

    Expert advice for Leflunomide

    • Do not drive or operate machinery because you may feel sleepy or dizzy while being treated with leflunomide.
    • Do not start leflunomide, if you have a kidney, liver, blood or lung problem; have low level of proteins in blood (hypoproteinemia), low level of any blood cells, or suffering from any disease with lowered immunity like tuberculosis or AIDS.
    • Do not start leflunomide, if you have intolerance to some sugars because this medicine contains lactose (a type of sugar).
    • Do not take leflunomide, if you are going to receive any live vaccine; or if you experience a widespread rash with blisters and peeling skin (Stevens-Johnson syndrome), widespread peeling of the superficial layers of the skin (toxic epidermal necrolysis),or drug reaction with eosinophilia and systematic symptoms (DRESS).
    • Avoid using leflunomide, if you are pregnant or planning to become pregnant, breastfeeding.

    Frequently asked questions for Leflunomide


    Q. Is Leflunomide an NSAID, immunosuppressant, blood thinner, chemotherapeutic agent?
    No, Leflunomide is not an NSAID, blood thinner or chemotherapeutic agent. It is an immunosuppressant anti-rheumatic drug
    Q. Can I take Tylenol (acetaminophen), or ibuprofen with leflunomide, or Arava?
    You can take Tylenol or ibuprofen with leflunomide or Arava which is brand name of leflunomide
    Q. Does Leflunomide cause weight or hair loss, bruising, high blood pressure, nausea, cancer, fatigue, or weight gain?
    Leflunomide may cause weight or hair loss, bruising, high blood pressure, and nausea (urge to vomit), but it is not known to cause weight gain, fatigue or cancer
    Show More
    Q. Does Leflunomide help psoriasis?
    Yes, Leflunomide is used in the treatment of psoriasis.

    Content on this page was last updated on 13 September, 2017, by Dr. Varun Gupta (MD Pharmacology)