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Calpol 250mg Tablet

Paracetamol (250mg)
Genuine
Authenticity Assured
NPPA Regulated
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Calpol 250mg Tablet is a widely prescribed medicine that helps to ease pain and bring down high body temperature (fever). In children, it treats conditions like headache, toothache, body ache, fever, and common cold.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 12 Nov 2025 | 11:55 AM (IST)
MRP ₹12.25
Gurgaon
 
 
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Calpol 250mg Tablet is currently sold out
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Saridon Head & Body Tablet
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Calpol 250mg Tablet
Calpol 250mg Tablet
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₹12.25
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Same composition
Saridon Head & Body Tablet
Saridon Head & Body Tablet
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Paracetamol (250mg)
by Bayer Pharmaceuticals Pvt Ltd
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₹41.9
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₹35.6

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General Information

Contains

Paracetamol (250mg)

Salt Synonyms

Acetaminophen

Marketer

Glaxo SmithKline Pharmaceuticals Ltd

Storage

Store below 30°C
The content is shown in English
Calpol 250mg Tablet image
Calpol 250mg Tablet image

Your child’s medicine at a glance

Calpol 250mg Tablet is given orally preferably at a fixed time every day. Though this medicine can be taken before or after food, it is best given after food as it can irritate the inner lining of an empty stomach. The dose and duration will depend upon your child’s age, body weight, and severity of the infection, so stick to the dose, time, and way prescribed by your child’s doctor. If your child vomits within 30 minutes of taking the medicine, let the child calm down and repeat the same dose. Redosing is not recommended if your child gets sick more than 30 minutes after taking a dose.

Do not give your child Calpol 250mg Tablet along with other medicines (many cold and flu medicines and other painkillers) that contain paracetamol, as this may result in overdosing and cause dangerous side effects such as hepatotoxicity (liver damage). Always check the ingredients of any other medicines before giving them to your child in combination with this medicine.

Generally, this medicine is well-tolerated by the children. However, temporary side effects such as indigestion, nausea, vomiting, and difficulty in sleeping, may occur in some children. Consult your doctor in case these episodes become bothersome for your child.

This medicine is often considered safe and effective but may not be suitable for everybody. Inform your doctor if your child is undergoing treatment for any blood-related disorder, is allergic to any medicinal compound, or has any birth defects, liver impairment, or kidney dysfunction. This will help your child’s doctor evaluate the dose and suitability of this medicine in a better way.

Uses of Calpol 250mg Tablet in children

Benefits of Calpol 250mg Tablet for your child

Pain relief
Calpol 250mg Tablet is a common painkiller used to treat aches and pains. It works by blocking chemical messengers in the brain that tell us we have pain. It is effective in relieving pain caused by headache, migraine, nerve pain, toothache, sore throat, period (menstrual) pains, arthritis, and muscle aches. This medicine is very widely used and very rarely causes side effects if taken at the right dosage. Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. It is also the first choice of painkiller during pregnancy or breastfeeding.
Treatment of Fever
Calpol 250mg Tablet is also used to reduce a high temperature (fever). It works by blocking the release of certain chemical messengers that cause fever. It may be prescribed alone or in combination with another medicine. You should take it regularly as advised by your doctor.

Side effects of Calpol 250mg Tablet in children

Calpol 250mg Tablet does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-
Common side effects of Calpol
  • Vomiting
  • Indigestion
  • Headache
  • Constipation
  • Itching
  • Insomnia (difficulty in sleeping)
  • Nausea

How can I give Calpol 250mg Tablet to my child?

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Calpol 250mg Tablet should be taken with or after food.

How Calpol Tablet works

Calpol 250mg Tablet possesses analgesic (pain-reliever) and antipyretic (lowers body temperature) properties. It provides relief by blocking certain chemical messengers and pathways in the brain that send signals about pain and fever.

All substitutes for Calpol 250mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Saridon Head & Body Tablet

by Bayer Pharmaceuticals Pvt Ltd
₹4.19/tablet
411% costlier
<h3 class=bodySemiBold>Saridon Head & Body Tablet</h3>

Arden 250mg Tablet

by Adonis Laboratories Pvt Ltd
₹2.12/tablet
159% costlier
<h3 class=bodySemiBold>Arden 250mg Tablet</h3>

Quick tips

  • Give Calpol 250mg Tablet to your child with food or milk to prevent an upset stomach.
  • Your child should not take more than four doses of this medicine in 24 hours, so wait up to 6 hours between doses.
  • Never give any other medicine formulation containing paracetamol along with this medicine as that may lead to serious side effects.
  • Inform the doctor if your child has liver disease as the dose may need to be adjusted.
  • If Calpol 250mg Tablet does not seem to be helping your child, contact your doctor for advice. Do not give extra doses.

Safety advice

Kidney

Kidney

CAUTION
Calpol 250mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
However, Calpol 250mg Tablet contains paracetamol which is considered the safest painkiller for children with kidney disease.
Liver

Liver

CAUTION
Calpol 250mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
However, the use of Calpol 250mg Tablet is not recommended in children with severe liver disease and active liver disease.

Interaction with drugs

Taking Calpol with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Lenalidomide (Oral Route)

Your doctor may monitor your liver function frequently.
Moderate

Bemiparin (Injection Route)

If concurrent use is essential, watch out for symptoms such as fatigue, nausea, loss of appetite, dark urine or jaundice and consult your doctor if you experience them. They may adjust the doses as per the observations.
Moderate

Certoparin (Injection Route)

If concurrent use is essential, watch out for symptoms such as fatigue, nausea, loss of appetite, dark urine or jaundice and consult your doctor if you experience them. They may adjust the doses as per the observations.
Moderate

Cholestyramine (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Paracetamol may increase the effect of Cholestyramine.
Moderate

Dalteparin (Injection Route)

If concurrent use is essential, watch out for symptoms such as fatigue, nausea, loss of appetite, dark urine or jaundice and consult your doctor if you experience them. They may adjust the doses as per the observations.

Frequently asked questions

Always follow your doctor's instructions regarding how much of the medicine to give and how often to give it. This depends on the strength of the medicine and the age of your child. You may also check the label or the leaflet inside the packaging for directions before use. The commonly recommended dose is 10-15 mg/kg per dose every 4 to 6 hours. In case you are not sure how much to give, consult your child’s doctor.
Calpol 250mg Tablet usually starts working within 30 to 60 mins of intake and shows its peak effect within 3 to 4 hours. Your child may start to feel better after a few doses. In case the pain or fever persists longer, consult your child’s doctor immediately.
If your child vomits within 30 minutes of taking Calpol 250mg Tablet, repeat the dose again. If it has been more than 30 minutes after taking Calpol 250mg Tablet and your child vomits, no need to repeat the dose and wait until it is time for the next dose. If you are not sure, consult your doctor.
You can give this medicine if your child has a temperature of 38.3°C (101°F) or higher. But, you must always try to speak to your child’s doctor first.
If the fever doesn't come down after the initial few doses, the cause might be an infection (virus or bacteria). It is advised to consult your child’s doctor for specific treatment.
You should only take four doses of Calpol 250mg Tablet in 24 hours. There should be a gap of at least 4-6 hours between two doses. Do not take it for more than 3 days without first talking to your doctor. Based on the dose, more than 250 mg/kg can lead to toxicity and can be potentially fatal. An overdose is capable of causing serious damage to the liver and kidneys. Inform your doctor immediately if you think you have given too much of this medicine to your child, even if your child seems well, because of the risk of delayed, serious liver damage.
Unless instructed by your doctor, your child should take a normal balanced diet while continuing this medicine as lack of nutrition can put your child at risk of developing medicinal toxicity.
Keep this medicine at room temperature in a dry place beyond the reach of the children.
It is advised to use Calpol 250mg Tablet with caution if the child has malnutrition, G6PD deficiency, liver disease, or any medicinal allergy. So, do not hesitate to share your child’s complete medical history with the doctor as that will help the doctor decide whether the medicine is safe for your child or not.
Calpol 250mg Tablet usually do not interfere with the ingredients in vaccines or cause a bad reaction in a child who has just been vaccinated. However, it is best if you let your child recover from the ongoing illness and finish the course of the medicine As soon as a child is feeling better the vaccine can and should be given.
If you vomit in less than 30 minutes after having a dose of Calpol 250mg Tablet tablets or syrup, retake the same dose again. If you vomit after 30 minutes of a dose, you do not need to take another one until the next standard dose.
Usually, you will start feeling better after about half an hour of taking a Calpol 250mg Tablet.
You should only take four doses of Calpol 250mg Tablet in 24 hours. There should be a gap of at least 4 hours between two doses. Do not take Calpol 250mg Tablet for more than 3 days without consulting a doctor first.
No, Calpol 250mg Tablet does not make babies sleepy. It is a pain-relieving medicine that is also used to control high fever.
Calpol 250mg Tablet is considered safe for children only when used as directed by the doctor.
No, Calpol 250mg Tablet is not an antibiotic. It works as a painkiller and fever-reducing medicine.
Ibuprofen and Calpol 250mg Tablet are safe medicines, but both should not be used together. Consult your doctor if you are not sure.
Calpol 250mg Tablet takes around 30-45 min to start working and show its effects. It is advised to take this medicine for the duration suggested by the doctor. Consult your doctor if you experience any bothersome side effects.
Overdose of Calpol 250mg Tablete may cause severe life-threatening liver injury. Taking more than the prescribed dose may also cause kidney injury, decreased platelet count, and even coma. Early symptoms of an overdose include nausea, vomiting, and general tiredness. Immediately consult a doctor or reach an emergency in case of a suspected overdose.

Fact Box

Chemical Class

P-Aminophenol Derivative

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

Action Class

Analgesic & Antipyretic-PCM

Related lab tests

Complete Blood Count

References

  1. Royal College of Paediatrics and Child Health. Medicines for Children - information for parents and carers. [Accessed 26 Dec. 2020] (online) Available from:
  2. Paracetamol [EMC Patient Leaflet]. Leeds, UK: Rosemont Pharmaceuticals Limited; 2019. [Accessed 26 Dec. 2020] (online) Available from:
  3. Aabideen K, Moulton LS, Sills J. Accidental staggered paracetamol overdose: An interesting case report. J Pharmacol Pharmacother. 2011;2(3):189-190. [Accessed 26 Dec. 2020] (online) Available from:
  4. Grosser T, Smyth E, FitzGerald G. Pharmacotherapy of Inflammation, Fever, Pain, and Gout. In: Brunton LL, Hilal-Dandan R, Knollmann BC (Editors). Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 13th ed. New York, New York: McGraw-Hill Medical; 2018.
  5. Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 982-84.
  6. Acetaminophen [Prescribing Information]. lake Zurich, IL: Fresenius Kabi USA, LLC; 2015. [Accessed 25 Jul. 2024] (online) Available from:
  7. Acetaminophen [Prescribing Information]. Yiyuan County, Shandong Province: Reyoung Pharmaceutical Co., Ltd.; 2023. [Accessed 11 Nov. 2025] (online). Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Glaxo SmithKline Pharmaceuticals Ltd
Address: Dr. Annie Besant Road, Mumbai - 400 030

Vendor Details

Country of origin: India

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