Assurance 20mg Tablet is a medicine used to treat high blood pressure in the blood vessels that supply the lungs (pulmonary arterial hypertension). It works by relaxing blood vessels, improving blood flow, reducing strain on the heart, and easing symptoms like breathlessness.

Assurance 20mg Tablet may be taken on an empty stomach or with a meal, but it should be taken at a fixed time each day. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. Follow the advice of your doctor. It is important to take this medicine regularly and for as long as you are advised, even if you feel well. Missing doses may lead to the worsening of your condition.

The most common side effects of this medicine include flushing, headache, muscle pain, diarrhea, pain in limbs, back pain, and blurred vision. If they bother you or if you experience any other side effects, talk to your doctor. They may be able to help you reduce or prevent the side effects.

This medicine can be dangerous to take along with medicines called nitrates (often given for chest pain). Do not take this medicine if you have severe heart or liver problems, if you have recently had a stroke or heart attack, or if you have low blood pressure. Let your doctor know if you suffer from these or any other health problems. Pregnant or breastfeeding women should also consult their doctor before taking it. Avoid drinking alcohol while taking this medicine, as it increases the chances of side effects.

Uses of Assurance Tablet

Treatment of Pulmonary arterial hypertension (PAH)

Benefits of Assurance Tablet

In Treatment of Pulmonary arterial hypertension (PAH)

Pulmonary arterial hypertension (PAH) can cause shortness of breath, tiredness, dizziness, chest pain and swelling in your ankles and legs. It is caused by thickening of walls of the arteries that supply your lungs making it hard for blood to get through. Assurance 20mg Tablet relaxes and widens blood vessels in the lungs. This helps reduce the strain on the heart and improves blood flow, leading to lowered blood pressure in the pulmonary arteries. By easing the workload on the heart and enhancing circulation, Assurance 20mg Tablet can improve exercise capacity, reduce symptoms like shortness of breath and fatigue, and enhance the overall quality of life for individuals with PAH.

Side effects of Assurance Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Assurance

Flushing (sense of warmth in the face, ears, neck and trunk)
Headache
Blurred vision
Muscle pain
Diarrhea
Indigestion
Limb pain

How to use Assurance Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Assurance 20mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Assurance Tablet works

Assurance 20mg Tablet is a phosphodiesterase (PDE-5) inhibitor. It works by relaxing the blood vessels in your lungs, thereby reducing the high blood pressure in the lungs. This allows your heart to work less to pump blood into your lungs.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Assurance 20mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Assurance 20mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CAUTION

Assurance 20mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Use of Assurance 20mg Tablet is not indicated in women.

Driving

UNSAFE

Assurance 20mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

Assurance 20mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Assurance 20mg Tablet is recommended.
However, inform your doctor if you have any underlying kidney disease. A lowering of dose may be considered if it is not well-tolerated.

Liver

CAUTION

Assurance 20mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Assurance 20mg Tablet may be needed. Please consult your doctor.

What if you forget to take Assurance Tablet?

If you miss a dose of Assurance 20mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Assurance 20mg Tablet

₹21.86/Tablet

Assurans Tablet

Cipla Ltd

₹25.67/tablet

17% costlier

Vasosure Tablet

Lupin Ltd

₹36.7/tablet

68% costlier

PAH 20 Tablet

MSN Laboratories

₹18/tablet

18% cheaper

Pulmoday 20mg Tablet

Aprica Pharmaceuticals Pvt Ltd

₹14.3/tablet

35% cheaper

Assurans Tablet

Cipla Ltd

₹19/tablet

13% cheaper

Quick tips

When taken regularly, Assurance 20mg Tablet can help improve your quality of life and exercise ability.
Do not use other medicines (nitrates or nitroglycerin) when taking Assurance 20mg Tablet, as it could drop your blood pressure to a dangerous level.
Do not consume alcohol while taking Assurance 20mg Tablet, as that may increase the blood pressure-lowering effects of Assurance 20mg Tablet.
Stop taking Assurance 20mg Tablet and immediately inform your doctor if you notice a loss of vision in one or both eyes or sudden loss of hearing with a ringing sensation in your ear.
Do not stop taking the medication suddenly without talking to your doctor, as that may lead to a worsening of your symptoms.

Fact Box

Chemical Class

Benzenesulfonamide Derivative

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Phosphodiesterase-V (PDE-5) Inhibitors

Interaction with drugs

Taking Assurance with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Escitalopram Oxalate (Oral Route) Life-threatening

Do not consume Escitalopram Oxalate with Sildenafil. Concomitant use may affect heart rhythm and may be fatal.

Chlorpromazine (Oral Route) Life-threatening

Do not consume Chlorpromazine with Sildenafil. Concomitant use may affect heart rhythm and can be fatal.

Ranolazine (Oral Route) Life-threatening

Do not consume Ranolazine with Sildenafil. Concomitant use may affect heart rhythm and may be fatal.

Amiodarone (Oral Route) Life-threatening

Do not consume Amiodarone with Sildenafil. Concomitant use may affect heart rhythm and may be fatal.

Pimozide (Oral Route) Life-threatening

Do not consume Pimozide with Sildenafil. Concomitant use may affect heart rhythm and may be fatal.

View all drug interactions

Patient concerns

Hello Dr. My Dad is facing High Pulmonary Hypertension of 63 and average is 32. He has liver cirrhosis as well, he is advised for liver transplant. As the PAH is high cannot proceed with the surgery. Can you please advise if there is any way out. Age : 49yrs. Medicines for heart taken at present is : Ambrisentan 5mg Assurance 20mg Trimium Inhaler.

Dr. Nabajit Talukdar

Cardiology

Currently no other treatment apart from ambrisantan n assurance will have to wait n see response to medicines if pulmonary pressure comes down only then surgery possible

How long take to cure viteligo Can you give assurance to fully cure

Dr. Saurav Arora

Homeopathy

Dear sir as Vitiligo is a chronic case it requires long case taking, examination and regular follow up, therefore, please visit a homeopath so that he can examine you and guide you accordingly. In homeopathy symptoms, history and examination is very important. In majority of cases, after a long case taking and case workout, we try to select a constitutional remedy which is used to treat the disease from its root cause. Taking a constitutional treatment shall also take care the reoccurrence of disease. Also as this is a chronic condition outcome is variable in each case

Suffering from allergy from last around two years, a red itching patches start appearing on different parts of the body , with burning itching .Scalp is also itching and same patches start appearing on head as well. I have to take citrazen tab twice or thrice in a week to control this and I know that consumption of this tablet on regular basis is not good for health but the itching is unbearable so that I have to take this. i already lost lots of hairs because of this, I tried so many doctors in allopathy, homeopathy as well in Ayurveda but nothing works till now. Will request you to kindly read the symptoms and suggest the best as per u.

Dr. Faran Siddiqui

Homeopathy

This seems to be Psoriasis. Psoriasis is a long drawn and constant treatment allopaths suppress this infection by steroids but it comes back with vengeance. Please post pics for assurance and be prep for continuous monitoring and treatment.

Can I take Assurance 20mg Tablet for the rest of my life?

Assurance 20mg Tablet is a prescription medicine and should only be taken for the duration that is advised by your doctor.

Why is the use of Assurance 20mg Tablet contraindicated with nitrates?

Use of Assurance 20mg Tablet is harmful for patients taking nitrates or blood pressure-lowering medicines, as their combined use can cause a severe fall in blood pressure, which can also result in death.

Why does Assurance 20mg Tablet cause a fall in blood pressure (hypotension)?

Assurance 20mg Tablet has the property of relaxing the smooth muscle of the blood vessels and widening them, which can cause a fall in blood pressure (hypotension). So, when used with blood pressure-lowering medicines or nitrates, it can cause a severe fall in blood pressure, which could be fatal. Assurance 20mg Tablet should not be taken if you are taking nitrates for chest pain or you have a history of heart attack or stroke in the past 6 months.

Is Assurance 20mg Tablet safe to use in patients with diabetes?

Yes, if prescribed by your doctor, then Assurance 20mg Tablet is safe to use in patients with diabetes.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Michel T, Hoffman BB. Treatment of Myocardial Ischemia and Hypertension. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 752-53.
Katzung BG, Chatterjee K. Vasodilator & the Treatment of Angina Pectoris. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 197.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1261-62.
Sildenafil [Prescribing Information]. New York, New York: Pfizer; 2014]. [Accessed 02 May 2025] (online) Available from:
Sildenafil [Prescribing Information]. Piscataway, NJ: Hetero Labs Limited; 2024. [Accessed 17 Mar. 2025] (online) Available from:

Marketer details

Name: Cipla Ltd

Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.