Arezil 5 Tablet

Reviewed By Dr. Mekhala Chandra, MD, MBBS

Last updated on 02 Feb 2026 | 07:42 PM (IST)

Arezil 5 Tablet is used to treat mild to moderate dementia in Alzheimer’s disease, a progressive illness that gradually affects memory and thinking. It does not cure this illness but may help improve memory, awareness, and other symptoms.

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Donepezil (5mg)

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General Information

Contains

Donepezil (5mg)

Marketer

Serotonin Pharmaceuticals LLP

Storage

Store below 25°C

The content is shown in English

Product introduction

Your doctor will explain how to take Arezil 5 Tablet. You may take it with food, preferably at night before going to bed. Follow the instructions carefully to get the most benefit. The dose may change from time to time to suit your individual needs. It can take up to a few weeks for symptoms to improve so keep taking your medicine regularly. You should not stop taking this medicine without consulting your doctor.

Some common side effects of this medicine include nausea, diarrhea, insomnia, vomiting, muscle cramps, fatigue, weight loss (anorexia), headache, loss of appetite, common cold, urinary incontinence, and rash. Drink plenty of fluids to keep yourself hydrated. You may have side effects more often when you start your treatment or when your dose is increased. Usually, the side effects will slowly go away as your body gets used to the Arezil 5 Tablet. If they are severe or will not go away, you should contact your doctor.

Before using Arezil 5 Tablet, you should tell your doctor if you have ever had heart problems, stomach ulcers, epilepsy, or asthma. It may also affect, or be affected by, some other drugs you are using so let your doctor know what these are to be safe. During pregnancy, this medicine should only be taken if it is advised.

Uses of Arezil Tablet

Alzheimer's disease

Benefits of Arezil Tablet

Alzheimer's disease
Alzheimer’s disease is a common cause of dementia, leading to memory loss, confusion, and difficulty with thinking and daily tasks. Arezil 5 Tablet is a medicine used to help manage symptoms of Alzheimer's-related dementia. It works by increasing the levels of a chemical in the brain called acetylcholine, which helps nerve cells communicate better. While it does not cure the disease, It can help improve memory, awareness, and the ability to perform daily activities in some people.

Side effects of Arezil Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Arezil

Weight loss
Insomnia (difficulty in sleeping)
Accidental injury
Common cold
Urinary incontinence
Rash
Nausea
Diarrhea

How to use Arezil Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Arezil 5 Tablet may be taken with or without food.

How Arezil Tablet works

Memory loss in Alzheimer’s disease occurs due to disturbances of signal transmission in the brain. Arezil 5 Tablet is a cholinesterase inhibitor. It works by increasing the levels of a chemical messenger (acetylcholine) involved in transmmission of nerve signals. This improves memory and thinking.

All substitutes for Arezil 5 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

You have been prescribed Arezil 5 Tablet to slow down the progression of Alzheimer's disease.
It does not cure Alzheimer's disease but may help improve brain function and ability to do daily activities.
Take it with or without food, preferably at night before going to bed.
It may cause diarrhea, nausea, and vomiting. Drink plenty of fluids to keep yourself hydrated while taking Arezil 5 Tablet.
Monitor your body weight regularly as both Arezil 5 Tablet and Alzheimer's disease can cause weight loss.
Do not drive or do anything that requires mental focus until you know how Arezil 5 Tablet affects you.
Be cautious while taking this medicine if you suffer from peptic ulcer as it may cause vomiting, stomach bleeding, stomach pain, or discomfort.
Inform your doctor if you develop muscle tremors, especially if you have Parkinson’s disease.
Inform your doctor if you experience seizures or convulsions while taking this medicine.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Arezil 5 Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Arezil 5 Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Arezil 5 Tablet during breastfeeding is not available. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Arezil 5 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

Arezil 5 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Arezil 5 Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Arezil with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Ramelteon (Oral Route)

Watch out for symptoms such as drowsiness, impaired movement, tiredness, nausea, palpitations, or numbness, and consult your doctor if you experience them. They may adjust the dose of Ramelteon accordingly. Donepezil may raise blood levels of Ramelteon.

Moderate

Atropine (Injection Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.

Moderate

Bethanechol (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Bethanechol may increase the effect of Donepezil.

Moderate

Carbachol (Injection Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Carbachol may increase the effect of Donepezil.

Moderate

Clomipramine (Oral Route)

If concurrent use is essential, please consult your doctor. They may monitor your treatment and adjust the doses as per the observations.

Frequently asked questions

Why is Arezil 5 Tablet taken at night?

Arezil 5 Tablet is recommended to be taken before going to bed to reduce gastrointestinal side effects or nausea, which is commonly seen in some patients in the first few weeks of treatment.

Do the gastrointestinal side effects due to Arezil 5 Tablet persist for a long time?

Gastrointestinal side effects may appear during the first few weeks of treatment with Arezil 5 Tablet. This can be minimized by taking Arezil 5 Tablet at bedtime and with food. Generally, these side effects are mild and disappear within a few weeks with continued treatment.

How long does it take for Arezil 5 Tablet to start working?

Within the first month of treatment with Arezil 5 Tablet, you may experience improvement in thinking and remembering (cognitive effect). However, it may take about 12 weeks to see the full benefits.

When should Arezil 5 Tablet be stopped?

Do not stop Arezil 5 Tablet without consulting your doctor. This medicine only helps to control your condition but does not cure it. Therefore, it may take several weeks to show benefits, so do not be discouraged if you do not see an improvement straight away. But, in case your condition starts worsening and you feel that it is no longer helping you, then you should consult a doctor before stopping it.

For how long does Arezil 5 Tablet stay in your system?

Arezil 5 Tablet gets removed from the body very slowly. It takes about two weeks or more for Arezil 5 Tablet to be completely removed from the system.

Does Arezil 5 Tablet cause depression?

No, Arezil 5 Tablet does not cause depression. If you are experiencing symptoms, then it could be due to existing Alzheimer’s disease.

What if I take more than the prescribed dose of Arezil 5 Tablet?

Taking more than the recommended dose of Arezil 5 Tablet may cause vomiting, increased sweating or saliva production, slow heartbeat, dizziness, difficulty in breathing, seizures or fits, weakness, low blood pressure, convulsions, and inability to control your bowel motions or passing of urine (incontinence). You should seek immediate help from a doctor or emergency service of a nearby hospital.

I have been taking indomethacin for arthritis. Can I take Arezil 5 Tablet?

Arezil 5 Tablet does not interfere with the working of indomethacin, but indomethacin individually increases the risk of stomach bleeding when taken for a long time. Therefore, if you experience any symptoms of stomach bleeding, consult your doctor immediately.

Does Arezil 5 Tablet cause hallucinations?

Hallucinations are a common side effect of Arezil 5 Tablet, though not everyone is affected. Other common psychiatric side effects include agitation, aggressive behavior, nightmares, and abnormal dreams.

Who should not take Arezil 5 Tablet?

Arezil 5 Tablet should not be taken by patients who have hypersensitivity to Arezil 5 Tablet hydrochloride, piperidine derivatives, or to any active ingredients used in the medicine. Also, it should not be used during pregnancy unless clearly necessary.

Can it cause insomnia?

Yes, insomnia (sleeplessness) is a common side effect of Arezil 5 Tablet. Dizziness and fainting can also be seen as common side effects. Though these side effects are common, they do not occur in everyone.

Fact Box

Chemical Class

N- benzylpiperidines

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Cholinesterase Inhibitors

References

Stahl SM, editor. Donepezil. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 199-202.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 426-27.
Donepezil hydrochloride. Woodcliff Lake, New Jersey: Eisai Inc.; 1996 [revised Feb. 2012]. [Accessed 25 Jan. 2019] (online) Available from:
Donepezil. Hatfield, Hertfordshire: Eisai Ltd.; 1997 [revised 11 May 2018]. [Accessed 25 Jan. 2019] (online) Available from:
Donepezil hydrochloride. South Ruislip, UK: Aurobindo Pharma - Milpharm Ltd.; 2013 [revised 23 Nov. 2017] [Accessed 19 Jun. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:
Donepezil hydrochloride [Prescribing Information]. Mahabubnagar, Telangana: Hetero Labs Limited; 2023. [Accessed 20 June 2023]. (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Serotonin Pharmaceuticals LLP
Address: B-808,EMPIRE BUSINESS HUB ,SCIENCE CITY ROAD, SOLA, AHMEDABAD-380060

Vendor Details

Country of origin: India

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Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Arezil 5 Tablet

Save more with additional offers

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Arezil Tablet

Benefits of Arezil Tablet

Side effects of Arezil Tablet

How to use Arezil Tablet

How Arezil Tablet works

All substitutes for Arezil 5 Tablet

Donpezem 5 Tablet

Donep 5 Tablet

Aricep 5 Tablet

Alzil 5 Tablet

Lapezil 5 Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Ramelteon (Oral Route)

Atropine (Injection Route)

Bethanechol (Oral Route)

Carbachol (Injection Route)

Clomipramine (Oral Route)

Frequently asked questions

Why is Arezil 5 Tablet taken at night?

Do the gastrointestinal side effects due to Arezil 5 Tablet persist for a long time?

How long does it take for Arezil 5 Tablet to start working?

When should Arezil 5 Tablet be stopped?

For how long does Arezil 5 Tablet stay in your system?

Does Arezil 5 Tablet cause depression?

What if I take more than the prescribed dose of Arezil 5 Tablet?

I have been taking indomethacin for arthritis. Can I take Arezil 5 Tablet?

Does Arezil 5 Tablet cause hallucinations?

Who should not take Arezil 5 Tablet?

Can it cause insomnia?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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