


Aprikinin Injection
Fosaprepitant (150mg)
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Stored between 2-8°C
Aprikinin Injection is a prescription medicine used to prevent nausea and vomiting caused by chemotherapy.
Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 31 Mar 2026 | 02:31 PM (IST)
Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 31 Mar 2026 | 02:31 PM (IST)
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General Information
Contains
Fosaprepitant (150mg)
Marketer
Miracalus Pharma Pvt Ltd
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English



Product introduction
Aprikinin Injection is given under the supervision of healthcare professional. Moreover, it is better to take it at a fixed time and you should not stop taking this medication suddenly without talking to your doctor. In case you have missed a dose than it is better to take it as soon as you remember it and finish the full course of treatment even if you feel better. Your doctor may advice for regular monitoring of liver function test while taking this medicine.
It has side effects like fatigue, headache, loss of appetite, constipation and hiccups. Dizziness and sleepiness may also occur as a side effect, so do not drive or do anything that requires mental focus until you know how this medicine affects you.
Uses of Aprikinin Injection
- Nausea and vomiting due to chemotherapy
Benefits of Aprikinin Injection
Nausea and vomiting due to chemotherapy
Chemotherapy-induced nausea and vomiting a distressing side effects experienced by cancer patients undergoing treatment. It can lead to dehydration, poor nutrition, and reduced quality of life, often interfering with the continuation of therapy. Aprikinin Injection helps prevent these symptoms by blocking neurokinin and effectively reducing both the immediate and delayed phases of nausea and vomiting. It improves patient comfort, supports better adherence to chemotherapy, and enhances overall treatment outcomes.
Chemotherapy-induced nausea and vomiting a distressing side effects experienced by cancer patients undergoing treatment. It can lead to dehydration, poor nutrition, and reduced quality of life, often interfering with the continuation of therapy. Aprikinin Injection helps prevent these symptoms by blocking neurokinin and effectively reducing both the immediate and delayed phases of nausea and vomiting. It improves patient comfort, supports better adherence to chemotherapy, and enhances overall treatment outcomes.
Side effects of Aprikinin Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Aprikinin
- Headache
- Hiccup
- Indigestion
- Fatigue
- Decreased appetite
- Constipation
How to use Aprikinin Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Aprikinin Injection works
Aprikinin Injection is an antiemetic medication. It works by blocking the action of a chemical messenger (neurokinin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy).
All substitutes for Aprikinin Injection
For information purposes only. Consult a doctor before taking any medicine.
Fosaport 150mg Injection
by Biocon
₹2671.87/injection
19% costlier
Aprecap 150mg Injection
by Glenmark Pharmaceuticals Ltd
₹2134/injection
5% cheaper
Fosa Injection
by Mylan Pharmaceuticals Pvt Ltd - A Viatris Company
₹1443/injection
36% cheaper
Apregen 150mg Injection
by Cellgen Biopharma
₹2803.13/injection
25% costlier
Apritant 150mg Injection
by MSN Laboratories
₹3057.19/injection
36% costlier
Quick tips
- Aprikinin Injection is given as a drip into the vein under the supervision of a doctor.
- It makes you feel dizzy or drowsy. Do not drive until you know how this medicine affects you.
- You will be monitored for liver functioning regularly while taking this medication.
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Aprikinin Injection. Please consult your doctor.

Pregnancy
SAFE IF PRESCRIBED
Aprikinin Injection is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.

Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Aprikinin Injection during breastfeeding is not available. Please consult your doctor.

Driving
UNSAFE
Aprikinin Injection may cause side effects that could affect your ability to drive.

Kidney
CAUTION
Aprikinin Injection should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver
CONSULT YOUR DOCTOR
There is limited data available on the use of Aprikinin Injection in patients with liver disease.
No dose adjustment is recommended in patients with moderate to severe liver disease.
No dose adjustment is recommended in patients with moderate to severe liver disease.
Interaction with drugs
Taking Aprikinin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe
Apalutamide (Oral Route)
Concomitant use should be avoided. Please consult with your doctor. Apalutamide may increase the metabolism of Fosaprepitant.
Moderate
Gliclazide (Oral Route)
Monitor your blood sugar levels regularly. Fosaprepitant may reduce blood levels of Gliclazide.
Moderate
Glibenclamide (Oral Route)
Talk to your doctor if you notice any unusual symptoms. Fosaprepitant may increase the effect of Glibenclamide.
Moderate
Glimepiride (Oral Route)
Talk to your doctor if you notice any unusual symptoms.Doctor may monitor your blood sugar level. Fosaprepitant may reduce blood levels of Glimepiride.
Moderate
Diltiazem (Oral Route)
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Fact Box
Chemical Class
Phenylmorpholines
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Neurokinin-1 (NK1) Receptor Antagonists
References
- McQuaid KR. Drugs Used in the Treatment of Gastrointestinal Diseases. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1086.
- Fosaprepitant dimeglumine. Hoddesdon, Hertfordshire: Merck Sharp & Dohme Limited; 2008 [revised 29 Nov. 2018]. [Accessed 29 Jan. 2019] (online) Availale from:
- Fosaprepitant. Highway, Greenville, NC: DSM Pharmaceuticals; 2008. [Accessed 28 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:

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Disclaimer
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Miracalus Pharma Pvt Ltd
Address: 213, Shivai Dongre Industrial Premises, Andheri - Kurla Road, Andheri(E), Mumbai - 400 072, Maharashtra, India.
Address: 213, Shivai Dongre Industrial Premises, Andheri - Kurla Road, Andheri(E), Mumbai - 400 072, Maharashtra, India.
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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