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Last updated on:
18 Feb 2019 | 06:31 PM (IST)
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Amitriptyline Hcl 25 mg Tablet


Overview

Uses of Amitriptyline Tablet

Amitriptyline Hcl 25 mg Tablet is used for neuropathic pain, preventive treatment of migraine and depression. It is used in patients intolerant of or unresponsive to alternative treatment options for depression.

Amitriptyline Tablet side effects

Common
  • Sleepiness
  • Blurred vision
  • Increased heart rate
  • Dryness in mouth
  • Constipation
  • Weight gain
  • Difficulty in urination
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)

How to use Amitriptyline Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amitriptyline Hcl 25 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Amitriptyline Tablet works

Amitriptyline Hcl 25 mg Tablet is a tricyclic antidepressant. It works by increasing the levels of chemical messengers in the brain that help in regulating mood and treat depression. It also stops the movement of pain signals from nerves to the brain thereby relieving neuropathic pain (pain from damaged nerves).

Amitriptyline Tablet related warnings

Alcohol
CAUTION
Amitriptyline Hcl 25 mg Tablet may cause excessive drowsiness and calmness with alcohol.
Pregnancy
WEIGH RISKS VS BENEFITS
Amitriptyline Hcl 25 mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
CAUTION
Amitriptyline Hcl 25 mg Tablet is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
Driving
Do not drive unless you are feeling well.
Amitriptyline Hcl 25 mg Tablet may impair your alertness which may affect your ability to drive.
Kidney
Amitriptyline Hcl 25 mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Amitriptyline Hcl 25 mg Tablet may not be needed in these patients. Please consult your doctor.
Liver
CAUTION
Amitriptyline Hcl 25 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Amitriptyline Hcl 25 mg Tablet may be needed. Please consult your doctor.
Use of Amitriptyline Hcl 25 mg Tablet is not recommended in patients with severe liver disease.

What if you miss a dose of Amitriptyline Tablet?

If you miss a dose of Amitriptyline Hcl 25 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Amitriptyline Hcl 25 mg Tablet
₹1/Tablet
₹2.39/Tablet
139% costlier
Amitone 25mg Tablet
Intas Pharmaceuticals Ltd
₹2.33/Tablet
133% costlier
Eliwel 25mg Tablet
Sun Pharmaceutical Industries Ltd
₹2.37/Tablet
137% costlier
Sarotena 25mg Tablet
Lundbeck India Pvt Ltd
₹2.37/Tablet
137% costlier
Amitryn 25mg Tablet
KC Laboratories
₹2.35/Tablet
135% costlier

Expert Advice

  • You have been prescribed Amitriptyline Hcl 25 mg Tablet for treatment of migraine/ neuropathic pain.
  • Take it at bedtime to avoid feeling sleepy during the day.
  • It may take 4 to 6 weeks for Amitriptyline Hcl 25 mg Tablet to start working.
  • Monitor your weight during the treatment as Amitriptyline Hcl 25 mg Tablet can cause weight gain and increased appetite.
  • It may change your urine color to blue-green.
  • It may cause sudden drop in your blood pressure. Rise slowly if you have been sitting or lying down.
  • Don't drive or do anything requiring concentration until you know how Amitriptyline Hcl 25 mg Tablet affects you.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
  • Avoid consuming alcohol when taking the Amitriptyline Hcl 25 mg Tablet as it may cause excessive drowsiness.

Interaction with Drugs

Taking Amitriptyline with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Panik
SERIOUS
Brand(s): Risure
SERIOUS
Brand(s): Shinosun
SERIOUS
Brand(s): Vlx
SERIOUS
Brand(s): Psycolith
SERIOUS
Brand(s): Psycopan
SERIOUS
Brand(s): Zosert
SERIOUS
Brand(s): Tremash
SERIOUS
Brand(s): Leparox, Prx
SERIOUS
Brand(s): Eurolam
SERIOUS

Patient Concerns

Questions Related to Amitriptyline

arrow
I suffered from brain stroke. How long can I use gabapentin 300 mg tablets ?
Dr. Anshul Varshney
General Physician
Hello, Welcome to 1mg. I am Anshul Varshney for your help. This medicine is used to calm down the neuropathic pain. You may take it till you feel better. Later your doctor may reduce the dose and stop it.
I m suffering due to pain in left testis, so I visited pgimer Chandigarh in urology deptt. There I had gone for dopler ultrasound testis and its reports are normal Now whenever I lay down at bed I felt a smaal lump in testis,when I touchdown it, the pain radiates in whole left testis Now I m feeling pain sometimes in both tastis Is it a sign of early vericoseal Or something else Pls. Suggest
Dr. Pranay Gandhi
Sexologist
it is a neuropathic pain and it won't show any abnormality in USG. i am worried about the lump u r talking about. its better if u consult a surgeon, PGIMER UROLOGY is the best place to go for examination. if they say its normal, its normal. for pain take pregaba m 1 od
arrow
Do you have any questions related to Amitriptyline Hcl 25 mg Tablet?

FAQs

Q. Can use of Amitriptyline lead to weight gain? If yes, how can it be managed?

You may gain weight after starting treatment with Amitriptyline. Consider managing<br>your weight by eating healthy diet, consuming low calorie food and including more<br>vegetables and fruits in your diet. Regular physical exercise will be very helpful.

Q. Is there anything I need to be careful about while on therapy with Amitriptyline?

Amitriptyline may cause drowsiness and dizziness, especially in the beginning of<br>the treatment. Do not drive or work with tools or machinery if your alertness is<br>affected. It is not advisable to drink alcohol during treatment with this medicine as it<br>might increase sleepiness.

Q. Can the use of Amitriptyline affect my sex life?

Yes, Amitriptyline can affect sex life in both men and women. It may cause<br>decrease sexual desire or there may be discomfort during intercourse. Men may<br>experience inability to develop or maintain erection during sexual activity and may<br>be unable to have orgasm. Do not stop taking the medicine but consult your doctor.

Q. I have been taking Amitriptyline for depression since a week and now I feel that my life has come to end and sometimes I want to harm myself. Is it because of the medicine? What should I do?

You should immediately consult your doctor or go to the hospital. Amitriptyline takes<br>about 2 weeks to show its effect, but may take longer, however, it may differ from<br>individual to individual. Therefore, when you start taking Amitriptyline, you may have<br>thoughts about killing or harming yourself. This is more common in people who<br>previously had suicidal tendencies or are young adults (less than 25 years old)

Q. Can Amitriptyline cause urinary problems?

Yes, Amitriptyline can cause urinary problems, which is more commonly seen in<br>elderly patients (more than 65 years old). The patient may complain of weak,<br>intermittent steam or may also develop urinary tract infection. You should consult<br>your doctor if you develop these symptoms.

Q. If my pain is not relieved, can I take more than the dose which is<br>recommended?

No, Amitriptyline should be strictly used only as prescribed by the doctor. If the dose<br>exceeds, you may develop drowsiness, confusion, difficulty in speech, dry mouth,<br>tired, difficulty in walking, fever, difficulty in breathing, blue discolouration of the skin<br>and decreased heart beat. In such a situation, contact your doctor immediately or<br>seek help of a family member or friend and go to the nearest hospital.

Q. Can use of Amitriptyline lead to weight gain? If yes, how can it be managed?

You may gain weight after starting treatment with Amitriptyline. Consider managing your weight by eating healthy diet, consuming low calorie food and including more vegetables and fruits in our diet. Regular physical exercise will be very helpful.

Q. Does Amitriptyline cause any effect on pregnancy or the new born?

Amitriptyline is not recommended during pregnancy unless your doctor considers it<br>clearly necessary and only after careful consideration of the benefit and risk. If you<br>have taken this medicine during the last part of the pregnancy, the new born may<br>develop symptoms such as irritability, rigidity, irregular body movements, irregular<br>breathing, poor drinking, loud crying, difficulty in urinating, and constipation.

Q. Is there anything I need to be careful about while on therapy with Amitriptyline?

Amitriptyline may cause drowsiness and dizziness, especially in the beginning of the treatment. Do not drive or work with tools or machinery if your alertness is affected. It is not advisable to drink alcohol during treatment with this medicine as it might increase sleepiness.

Q. Can I take Amitriptyline if I am breast feeding?

No, amitriptyline passes into breast milk and may harm your baby. Consult your<br>doctor and he will advise you whether to continue or stop breast-feeding, or stop<br>using this medicine taking into account the benefit of breast-feeding for your child<br>and the benefit of therapy for you.

Q. Can the use of Amitriptyline affect my sex life?

Yes, Amitriptyline can affect sex life in both men and women. It may cause decrease sexual desire or there may be discomfort during intercourse. Men may experience inability to develop or maintain erection during sexual activity and may be unable to have orgasm. Do not stop taking the medicine but consult your doctor.

Q. I have been taking Amitriptyline for depression since a week and now I feel that my life has come to end and sometimes I want to harm myself. Is it because of the medicine? What should I do?

Yes, Amitriptyline can affect sex life in both men and women. It may cause decrease sexual desire or there may be discomfort during intercourse. Men may experience inability to develop or maintain erection during sexual activity and may be unable to have orgasm. Do not stop taking the medicine but consult your doctor.

Q. Can Amitriptyline cause urinary problems?

Yes, Amitriptyline can cause urinary problems, which is more commonly seen in elderly patients (more than 65 years old). The patient may complain of weak, intermittent steam or may also develop urinary tract infection. You should consult your doctor if you develop these symptoms.

Q. If my pain is not relieved, can I take more than the dose which is recommended?

No, Amitriptyline should be strictly used only as prescribed by the doctor. If the dose exceeds, you may develop drowsiness, confusion, difficulty in speech, dry mouth, tired, difficulty in walking, fever, difficulty in breathing, blue discolouration of the skin and decreased heart beat. In such a situation, contact your doctor immediately or seek help of a family member or friend and go to the nearest hospital.

Q. Does Amitriptyline cause any effect on pregnancy or the new born?

Amitriptyline is not recommended during pregnancy unless your doctor considers it clearly necessary and only after careful consideration of the benefit and risk. If you have taken this medicine during the last part of the pregnancy, the new born may develop symptoms such as irritability, rigidity, irregular body movements, irregular breathing, poor drinking, loud crying, difficulty in urinating, and constipation.

Q. Can I take Amitriptyline if I am breast feeding?

No, Amitriptyline passes into breast milk and may harm your baby. Consult your doctor and he will advise you whether to continue or stop breast-feeding, or stop using this medicine taking into account the benefit of breast-feeding for your child and the benefit of therapy for you.

Q. I have been prescribed Amitriptyline for pain. When will I start feeling better?

You may start feeling better after 2 weeks of starting Amitriptyline. However, it may take 4-6 weeks to see full benefits.

Q. Can I take Amitriptyline off and on?

No, Amitriptyline should only be taken as directed by the doctor. Suddenly stopping the medicine may cause unpleasant symptoms e.g. headache, feeling unwell, sleeplessness and irritability. Talk to your doctor about the duration of your treatment and continue to take this medicine for as long as your doctor recommends.

Q. Can I stop taking Amitriptyline when my pain is relieved?

No, even if the pain is relieved, Amitriptyline should be continued as advised by the doctor. Consult your doctor for duration of the treatment since Amitriptyline needs to be gradually tapered (dose is reduced gradually).

Related Ayurvedic Ingredients

The medicine details are for information purpose only. Consult a doctor before taking any medicine.
Manufacturer/Marketer Address
1, Anurag Mansion, Shiv-Vallabh Road, Dahisar (E), Mumbai-400068.
MRP
10
10 tablets in 1 strip
SOLD OUT