Amitreat 25mg Tablet is a medicine used to treat depression by helping improve mood and reduce anxiety. It works by restoring the natural balance of certain brain chemicals that affect emotions. This helps relieve sadness, improves mental well-being, and makes daily life easier to manage.
Amitreat 25mg Tablet is normally taken before bedtime because it can make you feel sleepy. It can be taken with or without food. The dose and how often you need to take it will be decided by your doctor so that you get the right amount to control your symptoms. The initial dose should be increased with great caution under close supervision. This medicine may not work straight away and it could be several weeks before you get the full effects.
How long you need to use it will depend on what you are taking it for, but it is important to continue taking this medication even if you feel well. Do not stop taking the medicine suddenly without talking to your doctor. Stopping the medicine suddenly can worsen your conditions or cause other symptoms. Your dose may be modified or gradually decreased before stopping the medication. The most common side effects of this medicine include nausea, constipation, sweating, dry mouth, sleepiness, tremor, dizziness, headache, speech disorder, accommodation disorder, palpitations, increased heart rate, orthostatic hypotension, and nasal congestion. It may also make you aggressive or confused and can lead to weight gain in some people.
This medicine is not addictive, but you can experience additional side effects (withdrawal symptoms) if you stop taking it suddenly. Most of the common side effects tend to be mild. Your doctor may be able to suggest ways of preventing or reducing side effects if they bother you or do not go away. Serious side effects associated with this medicine are rare.
Amitreat 25mg Tablet helps relieve symptoms of depression by increasing the levels of certain mood-regulating chemicals in the brain. These include serotonin and norepinephrine. It helps improve mood, reduces feelings of sadness or hopelessness, and improves sleep quality. When used consistently as prescribed by the doctor, it can improve a patient’s daily functioning and overall quality of life.
Side effects of Amitreat Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Amitreat
Constipation
Dizziness
Dryness in mouth
Sleepiness
Headache
Difficulty in urination
How to use Amitreat Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amitreat 25mg Tablet may be taken with or without food.
How Amitreat Tablet works
Amitreat 25mg Tablet contains amitriptyline, an antidepressant (tricyclic antidepressant) that helps overcome depression. It works by increasing certain natural brain chemicals (serotonin and noradrenaline) that improve mood and reduce anxiety. This helps relieve depression and stabilize emotions.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Amitreat 25mg Tablet
Pregnancy
CONSULT YOUR DOCTOR
The safety of Amitreat 25mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding
CONSULT YOUR DOCTOR
Amitreat 25mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving
UNSAFE
Amitreat 25mg Tablet may cause side effects that could affect your ability to drive. Amitreat 25mg Tablet may impair your alertness which may affect your ability to drive.
Kidney
CAUTION
Amitreat 25mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver
CAUTION
Amitreat 25mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed. Use of Amitreat 25mg Tablet is not recommended in patients with severe liver disease.
What if you forget to take Amitreat Tablet?
If you miss a dose of Amitreat 25mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Amitreat 25mg Tablet may cause sleepiness. Take it at bedtime and do not drive or perform any activity requiring concentration until you know how it affects you.
Avoid consuming alcohol while taking Amitreat 25mg Tablet, as it may cause excessive sleepiness.
Monitor your weight during treatment, as this medicine can cause weight gain and increased appetite.
It may cause a sudden drop in blood pressure. Rise slowly if you have been sitting or lying down.
Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
Pay close attention to any changes, especially sudden changes, in mood, behavior, thoughts, or feelings. This is particularly important when the medicine is started or when the dose is changed.
This medication can significantly reduce saliva production, leading to dry mouth (xerostomia). Maintain strict oral hygiene by brushing twice daily with toothpaste and flossing regularly.
This medication may reduce tear production, leading to dry eyes. If you wear contact lenses, your doctor may advise using preservative-free lubricating eye drops to maintain proper eye and lens hygiene.
Fact Box
Chemical Class
Dibenzocycloheptenes
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Tricyclic Antidepressants (TCAs)
Interaction with drugs
Taking Amitreat with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not consume Moclobemide with Amitriptyline. If Moclobemide is essential, ensure a gap of at least 1 day after discontinuing Amitriptyline. Please consult your doctor.
Concomita... More
Do not consume Tranylcypromine with Amitriptyline. If Tranylcypromine is essential, ensure a gap of at least 2 weeks after discontinuing Amitriptyline. Please consult your doctor... More
Careful consideration is advised if you have epilepsy. Watch out for symptoms of serotonin syndrome, such as sedation, respiratory impairment, tremors, fever, diarrhea, or agitatio... More
If concurrent use is essential, watch out for symptoms such as sleepiness, dry mouth, impaired voluntary movements, weight gain, constipation, muscle stiffness or tremors and consu... More
What is Amitreat 25mg Tablet and what is it used for?
Amitreat 25mg Tablet is an antidepressant that contains amitriptyline and is primarily used to treat major depressive disorder. It is used to relieve symptoms of depression, improving mood, energy levels, and sleep quality. It works by increasing the levels of serotonin and norepinephrine in the brain, which helps improve mood and modulate pain signals. Sometimes, it is also used for insomnia, anxiety, and bedwetting in children.
What lifestyle changes should I make to get the maximum benefit of Amitreat 25mg Tablet?
Antidepressants, including Amitreat 25mg Tablet, are just one of several approaches used to treat depression. Certain lifestyle changes can help you get the maximum benefit from the medicine and support faster recovery. Staying physically active and eating a healthy diet can make a significant difference in how quickly you recover from depression. Practice yoga or take up an everyday hobby. Ensure that you get adequate sleep to calm your mind. Stay away from smoking and alcohol consumption, as these may worsen your depression.
Is there anything I need to be careful about while on treatment with Amitreat 25mg Tablet?
Amitreat 25mg Tablet may cause drowsiness and dizziness, especially at the beginning of treatment. Avoid driving or using machinery until you know how the medicine affects you. It is also not advisable to drink alcohol during treatment, as it may increase sleepiness.
Can the use of Amitreat 25mg Tablet affect my sex life?
Yes, Amitreat 25mg Tablet can affect sex life in both men and women. It may cause decreased sexual desire, or you may experience discomfort during intercourse. Men may experience difficulty developing or maintaining an erection and may be unable to have an orgasm. If you notice these symptoms, do not stop taking the medicine; consult your doctor. I have been taking Amitreat 25mg Tablet for depression for a week, and recently I have been wanting to harm myself.
What should I do? Is it because of the medicine?
Consult your doctor immediately. Suicidal thoughts may increase due to the underlying disease or the medicine. When starting treatment, some people may experience thoughts of harming themselves. This is more common in individuals with a prior history of suicidal tendencies or in young adults (below 25 years of age). However, the effect varies from person to person.
Does Amitreat 25mg Tablet cause any effect on pregnancy or on the newborn?
Consult your doctor to know the risks and benefits of continuing or starting Amitreat 25mg Tablet during pregnancy. If taken during pregnancy, it may cause preterm delivery and developmental issues. Babies born to mothers taking amitriptyline may experience temporary withdrawal symptoms in the first few days or weeks of life. These can include irritability, breathing problems, constant crying, and tremors.
How will Amitreat 25mg Tablet make me feel?
Antidepressants like Amitreat 25mg Tablet gradually help lift your mood. You may notice improved sleep and reduced anxiety. You may worry less about minor issues that previously bothered you. It will not make you feel excessively or unusually happy, but will help you feel like yourself again.
Is Amitreat 25mg Tablet a sleeping pill or a painkiller?
Amitreat 25mg Tablet is neither a conventional sleeping pill nor a typical painkiller. It contains amitriptyline, which is primarily used to treat mood disorders such as depression. However, doctors may sometimes prescribe it for other conditions, such as neuropathic pain.
Is Amitreat 25mg Tablet good for anxiety?
It is mainly an antidepressant that affects the levels of certain brain chemicals (serotonin and norepinephrine). It may help with anxiety, particularly when associated with depression or insomnia, because of its calming and sedative properties.
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References
Stahl SM, editor. Amitriptyline. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 25-30.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 58-59.
Amitriptyline. Princeton: Sandoz Inc; 2014. [Accessed on 19 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Amitriptyline. [Updated 2018 Oct 31]. [Accessed 19 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
Amitriptylin [Patient Information]. Versus Arthritis;. [Accessed 17 Mar. 2025] (online) Available from:
Amitriptyline Hydrochloride [Drug Label]. Ahmedabad, Gujarat: Intas Pharmaceuticals Limited; 2025. [Accessed 17 Mar. 2025] (online) Available from:
Marketer details
Name: Sanity Pharma
Address: 802, Safal Prelude, Nr. Ashwaraj Bunglow, Nr. Prahlad nagar Garden, Off - S.G. Highway, Ahmedabad-380015, Gujarat, India
Country of origin: India Expires on or after: August, 2026
A licensed vendor partner from your nearest location will deliver Amitreat 25mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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