Amantadin 100mg Tablet is used alone or in combination with other medicines to treat Parkinson’s disease. It works by increasing the levels of a chemical called dopamine in the brain, which is important for controlling movement.

Amantadin 100mg Tablet helps in improving muscle control and reducing stiffness by affecting specific brain chemicals. Take Amantadin 100mg Tablet as prescribed by your doctor, with or without food, preferably at the same time each day, to maintain a steady level of the medicine in your body. It can also be used to treat drug-induced movement disorders.

Take this medicine in the dose and duration as advised by your doctor. If you have missed a dose, take it as soon as you remember it. You should finish the full course of treatment even if you feel better. This medication must not be stopped suddenly without talking to your doctor.

Some common side effects of Amantadin 100mg Tablet include nausea, dizziness, and insomnia (difficulty sleeping). If you experience dizziness, rise slowly and do not drive or do anything that requires mental focus until you know how this medicine affects you.

This medicine may put you at a higher risk of having seizures, so talk to your doctor if you have any history of seizures or if you are taking any medication for seizures. Pregnant or breastfeeding women should consult a doctor before taking this medicine to make sure it is safe for them.

Uses of Amantadin Tablet

Treatment of Parkinson's disease

Benefits of Amantadin Tablet

In Treatment of Parkinson's disease

Amantadin 100mg Tablet helps improve muscle control, reduce stiffness, and enhance mobility in individuals with Parkinson's disease. This supports better coordination, reduced tremors, and improved overall daily functioning. When used regularly as advised by the doctor, it eases movement-related difficulties and improves overall quality of life.

Side effects of Amantadin Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Amantadin

Nausea
Dizziness
Insomnia (difficulty in sleeping)

How to use Amantadin Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amantadin 100mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Amantadin Tablet works

Amantadin 100mg Tablet works by increasing the levels of certain brain chemicals, such as dopamine, that help control movement and coordination. It helps improve muscle function, reduce stiffness, and enhance mobility in people with Parkinson’s disease and other movement disorders. It restores dopamine balance in the brain, making it easier to perform daily activities with better control and comfort.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Amantadin 100mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Amantadin 100mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Amantadin 100mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Amantadin 100mg Tablet may cause side effects which could affect your ability to drive.

Kidney

CAUTION

Amantadin 100mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Amantadin 100mg Tablet may be needed. Please consult your doctor.
Use of Amantadin 100mg Tablet is not recommended in patients with severe kidney disease.

Liver

CAUTION

Amantadin 100mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Amantadin 100mg Tablet may be needed. Please consult your doctor.
It may cause a transient increase in liver enzymes.

What if you forget to take Amantadin Tablet?

If you miss a dose of Amantadin 100mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Amantadin 100mg Tablet

₹0.96/Tablet

Parkitidin Tablet

Sun Pharmaceutical Industries Ltd

₹17/tablet

1671% costlier

Ensorex 100mg Tablet

Alteus Biogenics Pvt Ltd

₹16.27/tablet

1595% costlier

Amantex Tablet

Intas Pharmaceuticals Ltd

₹16.8/tablet

1650% costlier

Amantrel Tablet

Cipla Ltd

₹17.2/tablet

1692% costlier

Manotrel 100mg Tablet

Cmg Biotech Pvt Ltd

₹10.8/tablet

1025% costlier

Quick tips

Amantadin 100mg Tablet may cause blurring of vision or affect mental ability. Do not drive or do anything requiring concentration until you know how it affects you.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Amantadin 100mg Tablet may put you at a higher risk of having seizures. Talk to your doctor if you have a history of seizures or are taking medication for it.
Inform your doctor if you experience compulsive behaviors like gambling, increased sexual urges, binge eating, or overspending, as Amantadin 100mg Tablet may affect dopamine levels and cause impulse control issues.
Do not stop taking the medication suddenly without talking to your doctor.

Fact Box

Chemical Class

Synthetic Tricyclic Amine Derivative

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

NMDA (N-methyl-D-aspartate) Receptor Antagonists

Interaction with drugs

Taking Amantadin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Memantine (Oral Route) Moderate

Do not consume Memantine with Amantadine. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. If taken together, A... More

Bupropion (Oral Route) Moderate

Careful consideration is advised when taking Bupropion with Amantadine. If concurrent use is essential, watch out for symptoms such as shortness of breath, headache, nausea or blur... More

Amisulpride (Oral Route) Moderate

If concurrent use is essential, watch out for symptoms such as constipation, confusion or psychosis and consult your doctor if you experience them. They may monitor your treatment ... More

Amisulpride (Injection Route) Moderate

If concurrent use is essential, watch out for symptoms such as constipation, confusion or psychosis and consult your doctor if you experience them. They may monitor your treatment ... More

Aripiprazole (Oral Route) Moderate

If concurrent use is essential, watch out for symptoms such as constipation, confusion or psychosis and consult your doctor if you experience them. They may monitor your treatment ... More

View all drug interactions

Patient concerns

Parkinson's disease tremors ,Insomnia.

Dr. Ravi Shankar M.

Ayurveda

Use Dhanadanayanadi kashayam 15ml twice a day with 15 ml water before food and Zandopa 10 grams twice a day witk milk after food and Tab Dhanvantari Vati 1-0-1 after food for 2 months

Parkinson's disease for 25 yrs. Taking allopathy Suggestions needed

Dr. Deepak Kumar Soni

Ayurveda

Kindly consult to any good Ayuvedic Panchkarma center. Panchkarma therapy will give you some result .

Can Amantadin 100mg Tablet get you high?

The use of Amantadin 100mg Tablet may cause impulse control disorders in which you may have strong urges to gamble, increased sexual urges, intense urges to spend money, binge eating, and other intense urges. Additionally, there is the inability to control these urges. If such symptoms are experienced, then dose reduction or tapered discontinuation should be considered.

Is Amantadin 100mg Tablet a dopamine agonist?

Yes, Amantadin 100mg Tablet is a dopamine agonist. Dopamine is needed to control movements in the brain. Amantadin 100mg Tablet works by increasing the amount of dopamine, thereby helping in controlling the movements in Parkinson’s disease.

Does Amantadin 100mg Tablet cause fatigue?

Yes, Amantadin 100mg Tablet causes fatigue and sleepiness, which may affect some patients’ ability to drive and operate machinery safely.

Can I take Amantadin 100mg Tablet any time during the day? Should the dose be taken before meal?

Amantadin 100mg Tablet can be taken at any time during the day, with or without food. Try to take the medicine at about the same time each day, as directed by your doctor. Taking your medicine at the same time each day will have the best effect. It will also help you remember when to take your medicine.

Is Amantadin 100mg Tablet used for pain?

Though it is not an approved use, Amantadin 100mg Tablet is effective in relieving pain related to nerve disorders. Amantadin 100mg Tablet is a prescription medicine, and you should take it for the relief of pain only if advised by the doctor.

What happens when I stop taking Amantadin 100mg Tablet?

Do not stop taking this medicine or lower the dose without first checking with your doctor. If required, your doctor will gradually reduce the amount you take each day before stopping it completely. Abruptly stopping Amantadin 100mg Tablet may result in worsening of Parkinsonism. It may also cause delirium, agitation, delusions, hallucinations, paranoid reactions, stupor, anxiety, depression, or slurred speech.

Can Amantadin 100mg Tablet cause weight loss?

A decrease in weight and body mass index may occur with continued Amantadin 100mg Tablet usage. If you have any concerns regarding weight loss, consult your doctor or a nutritionist.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Aminoff MJ. Pharmacologic Management of Parkinsonism & Other Movement Disorders. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 477.
Standaert DG, Roberson ED. Treatment of Central Nervous System Degenerative Disorders. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 619.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 48-49.
Amantadine [Prescribing Information]. Bridgewater, New Jersey: Vertical Pharmaceuticals, LLC; 1966 [revised Feb. 2018]. [Accessed 19 Jun. 2019] (online) Available from:
Amantadine hydrochloride [Prescribing Information]. North Ryde, New South Wales: NOVARTIS Pharmaceuticals Australia Pty Limited; 2014. [Accessed 19 Jun. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
Amantadine Hydrochloride [Product Information]. Maple Grove, MN: Upsher-Smith Laboratories, LLC; 2022. [Accessed 09 Jun 2023] (online) Available from:
Amantadine Hydrochloride [Product Information]. Ahmedabad, Gujarat: Zydus Lifesciences Ltd.; 2025. [Accessed 14 Mar. 2025] (online) Available from:

Marketer details

Name: Cipla Ltd

Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Country of origin: India

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