Alkalith 450mg Tablet CR
Prescription Required
Product introduction
Alkalith 450mg Tablet CR is used in the treatment of bipolar disorder and mania in adults. It is sometimes used to treat other behavioral disorders as well. It reduces the frequency of manic episodes and decreases the intensity of those episodes that might occur.
Alkalith 450mg Tablet CR should be taken with food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Do not skip any doses and finish the full course of treatment even if you feel better. If you have missed a dose, take it as soon as you remember it. You should continue to take this medicine for as long as the doctor advises and do not stop taking it suddenly as it may result in harmful effects.
Side effects associated with the use of this medicine include tremors, slurred speech, uncoordinated body movements, nausea, Vomiting, acne, increased white blood cell count, and memory impairment. It may also cause hair loss, enlarged thyroid gland, skin rash, and increased thirst. This medicine may also cause weight gain and to control it, you should have a balanced diet and exercise regularly. If you have been taking this medicine for a long time then regular monitoring of thyroid and kidney function may be required.
Uses of Alkalith Tablet CR
Side effects of Alkalith Tablet CR
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Alkalith
- Tremors
- Slurred speech
- Uncoordinated body movements
- Nausea
- Acne
- Increased white blood cell count
- Memory impairment
- Hair loss
- Goiter (enlarged thyroid gland)
- Skin rash
- Increased thirst
- Weight gain
- Polyuria
- Diarrhea
- Vomiting
How to use Alkalith Tablet CR
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Alkalith 450mg Tablet CR is to be taken with food.
How Alkalith Tablet CR works
Alkalith 450mg Tablet CR works by suppressing the abnormal and excessive activity of the nerve cells in the brain.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Alkalith 450mg Tablet CR.
Pregnancy
CONSULT YOUR DOCTOR
Alkalith 450mg Tablet CR is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Alkalith 450mg Tablet CR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Alkalith 450mg Tablet CR may cause side effects which could affect your ability to drive.
Kidney
CAUTION
Alkalith 450mg Tablet CR should be used with caution in patients with kidney disease. Dose adjustment of Alkalith 450mg Tablet CR may be needed. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Alkalith 450mg Tablet CR is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Alkalith 450mg Tablet CR may not be needed in these patients. Please consult your doctor.
What if you forget to take Alkalith Tablet CR?
If you miss a dose of Alkalith 450mg Tablet CR, skip it and continue with your normal schedule. Do not double the dose.
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Quick tips
- Alkalith 450mg Tablet CR is one of the most effective long-term treatment for bipolar disorder.
- It may also be used for the treatment of mania.
- Your lithium blood levels, thyroid function, and kidney function may be monitored as long as you take this medicine.
- It may cause diarrhea and dehydration. Drink plenty of water and and use normal amounts of salt. Inform your doctor if you start or stop a low-salt diet.
- Monitor your weight during treatment as Alkalith 450mg Tablet CR can cause weight gain.
- Do not drive or do anything that requires mental focus until you know how it affects you.
- Inform your doctor if you have persistent stomach upset, problems with your speech, or extreme drowsiness. Your dose may need to be adjusted.
- Do not take Alkalith 450mg Tablet CR if you are pregnant or breastfeeding.
- Do not stop taking the medication suddenly without talking to your doctor.
Fact Box
Chemical Class
Organic Carbonic Acids
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Mood Stabilizers
Interaction with drugs
Taking Alkalith with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concomitant use may affect heart rhythm and can be fatal.
Do not consume Domperidone with Lithium carbonate.
Concurrent use may cause serious disturbance in heart rhythm.
If concurrent use is essential, watch out for symptoms such as double vision, weakness, dizziness, impaired coordinat
Concurrent use may cause serious disturbance in heart rhythm.
Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart
Concurrent use may cause serious disturbance in heart rhythm.
Careful consideration is advised when taking Haloperidol with Lithium carbonate. If concurrent use is essential, watc
Concomitant use may affect heart rhythm and can be fatal.
Do not consume Hydroxyzine with Lithium carbonate.
Patient concerns
FAQs
How quickly does Alkalith 450mg Tablet CR work?
It takes some time before you see improvement in your symptoms after taking Alkalith 450mg Tablet CR. Though it varies from person to person, it may take 1-3 weeks or longer for you to see the full benefits of Alkalith 450mg Tablet CR. Do not stop taking Alkalith 450mg Tablet CR if you feel you are not improving. Instead, discuss it with your doctor.
Does Alkalith 450mg Tablet CR make you sleepy?
Yes, Alkalith 450mg Tablet CR can cause nervous system disorders like sleepiness and dizziness and feeling confused. It can also cause rapid eye movements, blurred vision, or blind spots in your eyesight. If you experience any of these symptoms, consult your doctor. In addition, avoid driving or operating heavy machinery as it can be hazardous for you.
Is Alkalith 450mg Tablet CR bad for kidneys?
Yes, Alkalith 450mg Tablet CR may cause kidney problems. Alkalith 450mg Tablet CR is not prescribed in patients who already have severe kidney impairment. The kidney problems may not be reversible and the symptoms include swollen ankles, passing a lot of urine and feeling thirsty. Before starting treatment with Alkalith 450mg Tablet CR, your doctor will get blood tests done to see if your kidney function is normal. During Alkalith 450mg Tablet CR therapy, any gradual or sudden changes in renal function, even within the normal range, may indicate the need for re-evaluation of treatment.
Can Alkalith 450mg Tablet CR cause gain in weight?
Alkalith 450mg Tablet CR can cause both weight gain or weight loss. You should keep a check on your weight during Alkalith 450mg Tablet CR therapy. If you feel you are gaining or losing too much weight, consult your doctor who will assess whether the change in weight is due to Alkalith 450mg Tablet CR or some other reason.
What is the most important information I should know about Alkalith 450mg Tablet CR?
Alkalith 450mg Tablet CR therapy should only be started if adequate facilities for assessing Alkalith 450mg Tablet CR levels are available. This is because Alkalith 450mg Tablet CR toxicity is related to increased levels of Alkalith 450mg Tablet CR in blood. Alkalith 450mg Tablet CR toxicity can even occur at dose which is effective for treatment. Therefore, your doctor may closely monitor your Alkalith 450mg Tablet CR levels weekly until stabilization is achieved, then weekly for one month and then at monthly intervals thereafter.
How should Alkalith 450mg Tablet CR be taken?
Take Alkalith 450mg Tablet CR exactly as prescribed by your doctor. Check with your doctor if you are not sure. It is meant for oral administration and can be taken with or without food. However, if you start following a certain type of diet, talk to your doctor first. Any drastic changes in the amount of water you drink or amount of sodium (salt) in your diet may require more frequent monitoring of Alkalith 450mg Tablet CR levels.
Which medicines decrease Alkalith 450mg Tablet CR levels?
You should inform your doctor about the medicines you are taking before starting Alkalith 450mg Tablet CR since many medicines interfere with the working of Alkalith 450mg Tablet CR. Some medicines decrease the levels of Alkalith 450mg Tablet CR in blood which means that it will not work well. These include theophylline (for asthma), caffeine, anything containing sodium bicarbonate, or a special group of diuretics (water tablets) called carbonic anhydrase inhibitors and urea used to treat skin conditions.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Stahl SM, editor. Lithium. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 349-54.
- Meltzer H. Antipsychotic Agents & Lithium. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 502-504.
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Lithium. [Updated 2020 Jan 20]. [Accessed 20 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:
- Lithium Carbonate [Patient Information Leaflet]. Ahmedabad, Gujarat: Torrent Pharmaceuticals :Ltd.; 2022. [Accessed 20 Feb. 2024] (online) Available from:
Marketer details
Name: Alkem Laboratories Ltd
Address: Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Country of origin: India
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