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Agrogest M Tablet is a medicine used to treat breast cancer. This medicine helps to slow down the growth and multiplication of cancer cells.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 Nov 2025 | 03:05 PM (IST)
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Agrogest M Tablet image
Agrogest M Tablet image

Product introduction

Agrogest M Tablet should be taken as your doctor's advice. Your doctor will decide how much you need to take and for how much time. You may take it with or without food but better to take it at a fixed time. You should take this medicine for as long as it is prescribed for you.
  
Common side effects of this medicine include headache, dizziness, weakness, weight gain, and abdominal pain. Most of these are temporary and go away as soon as the body adjusts to the treatment. If any of these bothers you, let your doctor know. There may be ways of reducing or preventing them. It may cause irregular periods, bleeding, or spotting between menstrual periods. Inform your doctor if this occurs frequently. You should also inform the doctor immediately if you experience severe headaches, swelling in one leg, pain in breathing, or changes in vision or hearing.

Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Pregnant and breastfeeding women should not take this medicine.

Benefits of Agrogest M Tablet

Treatment of Abnormal uterine bleeding
Agrogest M Tablet is a synthetic progestin that replicates the effect of a natural female hormone called progesterone. It slows the growth of the lining of the womb before menstruation, which reduces the bleeding during menstruation. If heavy periods become such a problem that they interfere with your everyday life, then try taking things a little easier on those days. Some women find that relaxation techniques or yoga help them feel more relaxed and reduce stress. Getting a lot of exercise can also help.
Treatment of Endometriosis
Agrogest M Tablet contains progesterone, a female hormone that is important in the regulation of ovulation and menstruation. It is used to cause menstrual periods in women who have not reached menopause but are not having periods due to a lack of natural progesterone in the body. You should use the medicine as prescribed for it to be effective. Avoid any stress and follow your doctor’s instructions carefully. Improving weight and nutrition may be recommended in females with eating disorders or malnutrition to get the maximum benefit from Agrogest M Tablet.

Side effects of Agrogest M Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Agrogest M
  • Headache
  • Abdominal pain
  • Weakness
  • Dizziness
  • Irregular menstrual cycle
  • Nervousness
  • Weight gain
  • Change in appetite

How to use Agrogest M Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Agrogest M Tablet may be taken with or without food.

How Agrogest M Tablet works

Agrogest M Tablet is a hormone. It works by decreasing the levels of certain hormones required by breast cancer cells to grow. It may also interact with other hormones or have a direct effect on cancer to stop it from growing.

Quick tips

  • Stop taking Agrogest M Tablet and inform your doctor immediately if you get severe headaches, stabbing pains or swelling in one leg, pain on breathing, sudden changes in your vision or hearing, or yellowing of your skin or whites of your eyes.
  • It may cause bleeding  or spotting in between menstrual periods. Let your doctor know if this occurs frequently.
  • Use a non-hormonal method of contraception such as condoms to prevent pregnancy while you are taking this medication.
  • Do not take Agrogest M Tablet if you're pregnant or breastfeeding, have unusual vaginal bleeding, or have a history of blood clots, stroke, heart attack, liver problems, or bleeding problems.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Agrogest M Tablet. Please consult your doctor.
Pregnancy

Pregnancy

UNSAFE
Agrogest M Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

CAUTION
Agrogest M Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

UNSAFE
Agrogest M Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Agrogest M Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

UNSAFE
Agrogest M Tablet is unsafe to use in patients with liver disease and should be avoided.
AA

Interaction with drugs

Taking Agrogest M with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Letrozole (Oral Route)

Do not consume Letrozole with Medroxyprogesterone acetate if you have or had breast cancer. If essential, consult your doctor.
Severe

Phenobarbitone (Oral Route)

It is recommended to use barrier methods (like condoms), IUDs, or a depot for contraception. Your doctor may monitor your treatment closely and adjust the doses as per the observations. Use barrier methods (like condoms) for contraception to reduce the risk of HIV infection. Phenobarbitone may reduce the efficacy of Medroxyprogesterone acetate.
Severe

Phenobarbitone (Injection Route)

It is recommended to use barrier methods (like condoms), IUDs, or a depot for contraception. Your doctor may monitor your treatment closely and adjust the doses as per the observations. Use barrier methods (like condoms) for contraception to reduce the risk of HIV infection. Phenobarbitone may reduce the efficacy of Medroxyprogesterone acetate.
Severe

Mycophenolate mofetil (Oral Route)

Effective contraception must be used before, during, and for at least 6 weeks after stopping Mycophenolate mofetil. It is recommended to consult your doctor. Mycophenolate mofetil may reduce the efficacy of Medroxyprogesterone acetate.
Severe

Lorlatinib (Oral Route)

Do not consume Lorlatinib with Medroxyprogesterone acetate. Lorlatinib may reduce blood levels of Medroxyprogesterone acetate.

Frequently asked questions

Agrogest M Tablet contains Medroxyprogesterone, which is similar to the natural progesterone produced by your body. It is used to treat cases of breast cancer. Consult your doctor before taking Agrogest M Tablet.
You should take Agrogest M Tablet strictly as advised by your doctor. The dosage and duration of the Agrogest M Tablet would vary as per your medical condition. Your doctor may monitor you closely during your treatment with Agrogest M Tablet.
If you miss a dose, you should take it as soon as possible. However, if it is almost time for the next dose, skip the missed dose and continue the usual dosing schedule.
The common side effects of Agrogest M Tablet include vomiting, constipation, feeling sick, change in appetite, mood swings, weight fluctuation, and unusual vaginal bleeding or spotting. If any of the side effects persist, consult your doctor.
Depo-Provera is an injection form of Medroxyprogesterone which is used as a contraceptive injection for women. Whereas, Agrogest M Tablet is an oral form of Medroxyprogesterone and is not used as a contraceptive. Instead, it is used in the treatment of breast cancer.
Agrogest M Tablet is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.

Fact Box

Chemical Class

Gluco/mineralocorticoids, progestogin derivative

Habit Forming

No

Therapeutic Class

GYNAECOLOGICAL

Action Class

Progestins (First generation)

Related lab tests

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Agrosaf Pharmaceuticals
Address: Raman Tower, 2ND FLOOR, Sanjay Place, Agra, Uttar Pradesh 282002

Vendor Details

Country of origin: India
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