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Aeknil Injection

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS
Last updated on 25 Nov 2025 | 03:05 PM (IST)
Aeknil Injection helps in relieving moderate pain and reducing fever. It effectively alleviates pain and reduces fever for the short-term in cases following surgery or in cases where oral administration is not possible.
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PCM 150mg Injection
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Aeknil Injection
vial of 15 ml Injection
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PCM 150mg Injection
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Aeknil Injection image
Aeknil Injection image

Product introduction

Aeknil Injection is administered by a doctor or a nurse and should not be self-administered. Depending on the severity of your underlying illness, your doctor will decide the precise dose and schedule as per which this injection is to be given. It starts working within one hour. Inform your doctor if you are also taking other medications containing paracetamol to avoid an overdose. You should let your doctor know if your pain or fever does not subside.

Vomiting, difficulty sleeping, and constipation may be seen as side effects in some patients. Consult your doctor if these side effects do not resolve with time and persist for a longer duration of time. Inform your doctor immediately if any rash or allergic reaction is observed while taking this medicine.

Pregnant and nursing women should use it under medical supervision only. It should be used with caution in patients with liver and kidney disease or alcohol abuse. It is not recommended in patients with severe or active liver disease.

Uses of Aeknil Injection

Benefits of Aeknil Injection

Pain relief
Aeknil Injection is a common painkiller used to treat aches and pains. It works by blocking chemical messengers in the brain that tell us we have pain. It is effective in relieving pain caused by headache, migraine, nerve pain, toothache, sore throat, period (menstrual) pains, arthritis, and muscle aches. This medicine is very widely used and very rarely causes side effects if taken at the right dosage. Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. It is also the first choice of painkiller during pregnancy or breastfeeding.
Treatment of Fever
Aeknil Injection is also used to reduce a high temperature (fever). It works by blocking the release of certain chemical messengers that cause fever. It may be prescribed alone or in combination with another medicine. You should take it regularly as advised by your doctor.

Side effects of Aeknil Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Aeknil
  • Headache
  • Constipation
  • Anxiety
  • Itching
  • Insomnia (difficulty in sleeping)
  • Nausea
  • Vomiting

How to use Aeknil Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Aeknil Injection works

Aeknil Injection is an analgesic (pain reliever) and anti-pyretic (fever reducer). It works by blocking the release of certain chemical messengers that cause pain and fever.

All substitutes for Aeknil Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Aeknil Injection helps in relieving moderate pain and fever for the short-term, especially following surgery.
  • Inform your doctor if you are also taking other medications containing paracetamol.
  • Inform your doctor if you suffer from liver disease, severe kidney disease, or alcohol abuse.
  • Inform your doctor if you experience symptoms such as feeling or being sick, weight loss, pale skin (pallor), or abdominal pain within the first 24 hours as it indicates an overdose.
     
  • Your doctor may regularly monitor your kidney function, liver function and levels of blood components if you are taking this medicine for long-term treatment.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Aeknil Injection
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
Aeknil Injection is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Aeknil Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

SAFE
Aeknil Injection does not usually affect your ability to drive.
Kidney

Kidney

CAUTION
Aeknil Injection should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
However, Aeknil Injection contains paracetamol which is considered the safest painkiller for kidney disease patients.
Liver

Liver

CAUTION
Aeknil Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.
However, the use of Aeknil Injection is not recommended in patients with severe liver disease and active liver disease.

Interaction with drugs

Taking Aeknil with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Imatinib mesylate (Oral Route)

Talk to your doctor if you notice any unusual symptoms. Paracetamol may decrease the metabolism of Imatinib mesylate.
Moderate

Bemiparin (Injection Route)

If concurrent use is essential, watch out for symptoms such as fatigue, nausea, loss of appetite, dark urine or jaundice and consult your doctor if you experience them. They may adjust the doses as per the observations.
Moderate

Certoparin (Injection Route)

If concurrent use is essential, watch out for symptoms such as fatigue, nausea, loss of appetite, dark urine or jaundice and consult your doctor if you experience them. They may adjust the doses as per the observations.
Moderate

Dalteparin (Injection Route)

If concurrent use is essential, watch out for symptoms such as fatigue, nausea, loss of appetite, dark urine or jaundice and consult your doctor if you experience them. They may adjust the doses as per the observations.
Moderate

Enoxaparin (Injection Route)

If concurrent use is essential, watch out for symptoms such as fatigue, nausea, loss of appetite, dark urine or jaundice and consult your doctor if you experience them. They may adjust the doses as per the observations.

Frequently asked questions

Aeknil Injection should be administered under the supervision of a trained healthcare professional or a doctor only. It should not be self-administered. The dose of the medicine will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Aeknil Injection.
If you vomit in less than 30 minutes after having a dose of Aeknil Injection tablets or syrup, retake the same dose again. If you vomit after 30 minutes of a dose, you do not need to take another one until the next standard dose.
Overdose of Aeknil Injectione may cause severe life-threatening liver injury. Taking more than the prescribed dose may also cause kidney injury, decreased platelet count, and even coma. Early symptoms of an overdose include nausea, vomiting, and general tiredness. Immediately consult a doctor or reach an emergency in case of a suspected overdose.
Usually, you will start feeling better after about half an hour of taking a Aeknil Injection.
No, Aeknil Injection is not an antibiotic. It works as a painkiller and fever-reducing medicine.
Aeknil Injection is considered safe for children only when used as directed by the doctor.
Ibuprofen and Aeknil Injection are safe medicines, but both should not be used together. Consult your doctor if you are not sure.
No, Aeknil Injection does not make babies sleepy. It is a pain-relieving medicine that is also used to control high fever.
If you vomit in less than 30 minutes after having a dose of Aeknil Injection tablets or syrup, retake the same dose again. If you vomit after 30 minutes of a dose, you do not need to take another one until the next standard dose.
Usually, you will start feeling better after about half an hour of taking a Aeknil Injection.
You should only take four doses of Aeknil Injection in 24 hours. There should be a gap of at least 4 hours between two doses. Do not take Aeknil Injection for more than 3 days without consulting a doctor first.
No, Aeknil Injection does not make babies sleepy. It is a pain-relieving medicine that is also used to control high fever.
Aeknil Injection is considered safe for children only when used as directed by the doctor.
No, Aeknil Injection is not an antibiotic. It works as a painkiller and fever-reducing medicine.
Ibuprofen and Aeknil Injection are safe medicines, but both should not be used together. Consult your doctor if you are not sure.
Aeknil Injection takes around 30-45 min to start working and show its effects. It is advised to take this medicine for the duration suggested by the doctor. Consult your doctor if you experience any bothersome side effects.
Overdose of Aeknil Injectione may cause severe life-threatening liver injury. Taking more than the prescribed dose may also cause kidney injury, decreased platelet count, and even coma. Early symptoms of an overdose include nausea, vomiting, and general tiredness. Immediately consult a doctor or reach an emergency in case of a suspected overdose.

Fact Box

Chemical Class

1- hydroxy- 2- unsubstituted benzenoids

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

Action Class

Analgesic & Antipyretic-PCM

Related lab tests

References

  1. Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 635-36.
  2. Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 982-84.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 8-12.
  4. Paracetamol/Acetaminophen. San Diego, CA: Cadence Pharmaceuticals, Inc; 1951 [revised Nov. 2010]. [Accessed 02 Apr. 2019] (online) Available from:
  5. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 02 Apr. 2019] (online) Available from:
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:
  7. Acetaminophen [Prescribing Information]. Hazelwood, MO: Mallinckrodt Hospital Products Inc.; 2018. [Accessed 25 Jul. 2024] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Therapeutic Pharmaceuticals
Address: No. 951, Marathe Udyog Bhavan, A. M. Marg, Prabhadevi,Mumbai - 400025, Maharashtra, India

Vendor Details

Country of origin: India
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