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Pentasa 2gm Prolonged Release Granules

Mesalazine (2gm)

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Pentasa 2gm Prolonged Release Granules is an anti-inflammatory medicine used to treat a type of bowel disease known as ulcerative colitis. It helps to reduce symptoms such as diarrhea, bleeding and stomach pain by reducing inflammation in the bowel.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 Nov 2025 | 03:05 PM (IST)

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2 gm Granules

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Gurgaon

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Pentasa 2gm Prolonged Release Granules

sachet of 2 gm Granules

₹40.95 per gm

₹96.3

~~₹107.91~~

11% off

₹81.9

order for

₹1200

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by Ferring Pharmaceuticals

21% lower price

Mesacol CR 2gm Granules

packet of 2 gm Granules

₹32.45 per gm

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~~₹84.38~~

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₹1200

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by Sun Pharmaceutical Industries Ltd

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General Information

Storage

Store below 25°C

The content is shown in English

Pentasa 2gm Prolonged Release Granules image

Product introduction

Pentasa 2gm Prolonged Release Granules may also be used to treat another type of bowel disease known as Crohn’s ileocolitis. It should be taken with food. The dose will depend on what you are being treated for but take it exactly as your doctor prescribes. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen.

The most common side effects of this medicine include nausea, diarrhea, stomach pain, headache, itching, flatulence, and vomiting. If these symptoms bother you, do not go away, or get worse, let your doctor know. There may be ways of reducing or preventing them. Some people may get a severe allergic reaction that needs urgent medical attention. Contact your doctor immediately if you notice symptoms like swelling of the face, tongue, throat, or lips, unusual bleeding, bruising, rash, fever, sore throat, or excessive tiredness.

Before taking it, tell your doctor if you have any kidney or liver problems or a blockage in your stomach. Your age may also be a factor in deciding whether this medicine is suitable. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.

Uses of Pentasa Granules

Benefits of Pentasa Granules

Ulcerative colitis
Ulcerative colitis is a form of inflammatory bowel disease (IBD) that causes inflammation and ulcers in the colon and rectum. Pentasa 2gm Prolonged Release Granules helps reduce the inflammation in the intestinal lining by targeting the disease locally. Reduction in inflammation promotes mucosal healing and causes symptoms like abdominal pain, diarrhea, and rectal bleeding to subside.

Crohn’s disease
Crohn’s disease is a type of inflammatory bowel disease that can affect any part of the digestive tract, causing symptoms like abdominal pain, diarrhea, and fatigue. Pentasa 2gm Prolonged Release Granules is used in mild to moderate cases to reduce inflammation and manage flare-ups. It can help prevent disease progression, reduce the need for steroids, and support intestinal health over time.

Side effects of Pentasa Granules

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pentasa

Flatulence
Headache
Vomiting
Diarrhea
Nausea
Abdominal pain
Rash
Stomach pain/epigastric pain

How to use Pentasa Granules

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Empty the granules in a glass of water/milk, stir it and consume immediately. Pentasa 2gm Prolonged Release Granules may be taken with or without food.

How Pentasa Granules works

Pentasa 2gm Prolonged Release Granules is an aminosalicylate. It works by suppressing the production of chemical messengers (prostaglandins) that cause inflammation (swelling) in the intestines. This reduces ulceration, bleeding and stomach pain, and prevents future flare-ups of the disease.

All substitutes for Pentasa 2gm Prolonged Release Granules

For information purposes only. Consult a doctor before taking any medicine.

Mesacol CR 2gm Granules

by Sun Pharmaceutical Industries Ltd

₹84.38/granules

22% cheaper

Quick tips

You have been prescribed Pentasa 2gm Prolonged Release Granules for treating and lowering the symptoms of mild inflammatory bowel disease such as ulcerative colitis.
Your doctor may monitor your kidney and liver functions before you start treatment with this medicine and regularly thereafter. Inform your doctor if you have severely decreased kidney or liver function.
Do not take Pentasa 2gm Prolonged Release Granules if you are allergic to aspirin or if you have blood disorders.
Do not stop taking the medication suddenly without talking to your doctor.
You have been prescribed Pentasa 2gm Prolonged Release Granules for treating and lowering the symptoms of mild inflammatory bowel disease such as ulcerative colitis.
Take it with food. Do not break, chew, or crush the tablets or granules. Swallow them whole with plenty of water.
Do not take antacids with Pentasa 2gm Prolonged Release Granules as it can make your inflammation worse.
Your doctor may monitor your kidney and liver functions before you start treatment with this medicine and regularly thereafter. Inform your doctor if you have severely decreased kidney or liver function.
Do not take Pentasa 2gm Prolonged Release Granules if you are allergic to aspirin or if you have blood disorders.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Pentasa 2gm Prolonged Release Granules.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Pentasa 2gm Prolonged Release Granules during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Pentasa 2gm Prolonged Release Granules may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
If you are taking Pentasa 2gm Prolonged Release Granules, monitor the baby for diarrhea.

Driving

SAFE

Pentasa 2gm Prolonged Release Granules does not usually affect your ability to drive.

Kidney

CAUTION

Pentasa 2gm Prolonged Release Granules should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Pentasa 2gm Prolonged Release Granules is not recommended in patients with severe kidney disease.

Liver

CAUTION

Pentasa 2gm Prolonged Release Granules should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Pentasa with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Clozapine (Oral Route)

Your doctor may monitor your blood cell count and adjust the doses as per the observations.

Moderate

Azathioprine (Oral Route)

If concurrent use can not be avoided, your doctor may monitor your blood cell counts.

Moderate

Deferiprone (Oral Route)

If concurrent use can not be avoided, your doctor may monitor your blood cell counts.

Moderate

Mercaptopurine (Oral Route)

If concurrent use cannot be avoided, your doctor may monitor your blood cell counts.

Mild

Chlorpromazine (Oral Route)

Talk to your doctor if you notice any unusual symptoms.

Frequently asked questions

My symptoms have improved can I stop taking Pentasa 2gm Prolonged Release Granules?

Continue to take Pentasa 2gm Prolonged Release Granules as advised by the doctor, even if you feel better at the beginning of your treatment. Do not stop taking Pentasa 2gm Prolonged Release Granules without consulting your doctor.

Can I drink alcohol while taking Pentasa 2gm Prolonged Release Granules?

You should avoid alcohol if you have ulcerative colitis, as alcohol will irritate your stomach and intestine which will worsen your condition. Although alcohol does not interfere with the working of Pentasa 2gm Prolonged Release Granules, you should consult your doctor before taking alcohol.

Does Pentasa 2gm Prolonged Release Granules cause joint pain?

Yes, Pentasa 2gm Prolonged Release Granules may cause joint pain. If the pain continues and bothers you inform your doctor.

When is the best time to take Pentasa 2gm Prolonged Release Granules?

Take Pentasa 2gm Prolonged Release Granules exactly as directed by your doctor.

Fact Box

Chemical Class

Aminobenzoic acids

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

5-Aminosalicylic Acid (5-ASA)

Related lab tests

Anti Neutrophilic Cytoplasmic Antibody - P

Anti Saccharomyces Cerevisiae (ASCA), IgA

Anti Saccharomyces Cerevisiae (ASCA), IgG

C- Reactive Protein Quantitative

Erythrocyte Sedimentation Rate

References

User feedback

Patients taking Pentasa 2gm Prolonged Release Granules

Twice A Day

86%

Once A Day

14%

What are you using Pentasa Granules for?

Ulcerative colitis

59%

Crohn’s disease

39%

Others

How much was the improvement?

Average

44%

Excellent

43%

Poor

12%

What were the side-effects while using Pentasa 2gm Prolonged Release Granules?

Abdominal pain

20%

Headache

20%

Vomiting

10%

Flatulence

10%

Nausea

10%

How do you take Pentasa Granules?

With food

82%

With or without food

14%

Empty stomach

Please rate Pentasa 2gm Prolonged Release Granules on price

Expensive

76%

Average

19%

Not Expensive

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Ferring Pharmaceuticals
Address: K-28/1, ADDITIONAL MIDC , ANAND NAGAR , AMBERNATH - 421506 , INDIA

Vendor Details

Country of origin: Switzerland
A licensed vendor partner from your nearest location will deliver Pentasa 2gm Prolonged Release Granules. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Pentasa 2gm Prolonged Release Granules

Save more with additional offers

General Information

Contains

Salt Synonyms

Marketer

Storage

Product introduction

Uses of Pentasa Granules

Benefits of Pentasa Granules

Side effects of Pentasa Granules

How to use Pentasa Granules

How Pentasa Granules works

All substitutes for Pentasa 2gm Prolonged Release Granules

Mesacol CR 2gm Granules

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Clozapine (Oral Route)

Azathioprine (Oral Route)

Deferiprone (Oral Route)

Mercaptopurine (Oral Route)

Chlorpromazine (Oral Route)

Frequently asked questions

My symptoms have improved can I stop taking Pentasa 2gm Prolonged Release Granules?

Can I drink alcohol while taking Pentasa 2gm Prolonged Release Granules?

Does Pentasa 2gm Prolonged Release Granules cause joint pain?

When is the best time to take Pentasa 2gm Prolonged Release Granules?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Anti Neutrophilic Cytoplasmic Antibody - P

Anti Saccharomyces Cerevisiae (ASCA), IgA

Anti Saccharomyces Cerevisiae (ASCA), IgG

C- Reactive Protein Quantitative

Erythrocyte Sedimentation Rate

References

User feedback

Patients taking Pentasa 2gm Prolonged Release Granules

What are you using Pentasa Granules for?

How much was the improvement?

What were the side-effects while using Pentasa 2gm Prolonged Release Granules?

How do you take Pentasa Granules?

Please rate Pentasa 2gm Prolonged Release Granules on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests