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Kerendia 20mg Tablet

Written By Dr. Lipika Khurana, PGDHHM, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 25 Nov 2025 | 03:05 PM (IST)
Kerendia 20mg Tablet is medicine used in the treatment of chronic kidney disease (CKD) caused by type 2 diabetes (T2D). It works by blocking a certain hormone in the body, which can help prevent the kidneys from getting worse and reduce the risk of heart-related issues like heart attacks and heart failure.
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General Information

The content is shown in English
Kerendia 20mg Tablet image
Kerendia 20mg Tablet image
Kerendia 20mg Tablet image
Kerendia 20mg Tablet image
Kerendia 20mg Tablet image

Product introduction

Kerendia 20mg Tablet may be taken with or without food. Your doctor will decide the dose and duration of the medicine for you. The doctor may closely monitor your blood pressure, heart rate, electrocardiogram (ECG), estimated glomerular filtration rate (eGFR), urine albumin‐to‐creatinine ratio (UACR), and potassium level till you become stable. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection.


Common side effects of this medicine include high potassium level, low blood pressure, and low sodium level in the body. If you experience any of these side effects, consult your doctor. They may be able to help by reducing the dosage, or by prescribing you an alternate medicine.


This medicine may not be suitable for everybody. Let your doctor know if you are suffering from any kidney or liver disease. Let your doctor also know about all the other medicines you are taking for any medical conditions. Pregnant and breastfeeding women should consult their doctors before taking this medicine.

Uses of Kerendia Tablet

Benefits of Kerendia Tablet

Treatment of Chronic kidney disease
Kerendia 20mg Tablet is beneficial in reducing the risk of various complications in adults with chronic kidney disease (CKD) linked to type 2 diabetes (T2D). It helps prevent sustained decline in kidney function, progression to end-stage kidney disease, and cardiovascular-related events such as heart attack and heart failure. Additionally, Kerendia 20mg Tablet reduces the likelihood of hospitalization due to heart failure and lowers the risk of cardiovascular death. This way it helps manage CKD in diabetic patients, potentially improving both kidney and heart health outcomes.

Side effects of Kerendia Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Kerendia
  • Increased potassium level in blood
  • Hypotension (low blood pressure)
  • Decreased sodium level in blood

How to use Kerendia Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Kerendia 20mg Tablet may be taken with or without food.

How Kerendia Tablet works

Kerendia 20mg Tablet is a nonsteroidal, selective antagonist of the mineralocorticoid receptor (MR). This receptor, usually activated by hormones like aldosterone and cortisol, helps in controlling sodium levels in the body. Kerendia 20mg Tablet blocks and prevent this receptor from overactivation, which can damage different parts of the body such as the kidneys, heart, and blood vessels.

All substitutes for Kerendia 20mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • For patients who are unable to swallow whole tablets, Kerendia 20mg Tablet may be crushed and mixed with water or soft foods, before taking it.
  • Inform your doctor if you are taking potassium supplements or any other medications for high blood pressure or heart disease.
  • Women of childbearing potential should use effective contraception during the treatment to avoid getting pregnant.
  • Kerendia 20mg Tablet contains lactose; inform your doctor if you have lactose intolerance.
  • Lactating women should exercise cautions while on treatment with this medicine.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Kerendia 20mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Kerendia 20mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CAUTION
Kerendia 20mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Kerendia 20mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

SAFE IF PRESCRIBED
Kerendia 20mg Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended.
Liver

Liver

SAFE IF PRESCRIBED
Kerendia 20mg Tablet is safe to use in patients with liver disease. No dose adjustment is recommended.

Interaction with drugs

Taking Kerendia with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Apalutamide (Oral Route)

Concomitant use should be avoided. Please consult with your doctor. Apalutamide may increase the metabolism of Finerenone.
Moderate

Vilazodone (Oral Route)

If concurrent use is essential, your doctor may monitor your blood sodium levels closely.
Moderate

Aceclofenac (Oral Route)

If concurrent use is essential, your doctor may monitor your potassium levels along with your overall treatment and adjust the doses as per the observations.
Moderate

Aceclofenac (Injection Route)

If concurrent use is essential, your doctor may monitor your potassium levels along with your overall treatment and adjust the doses as per the observations.
Moderate

Aceclofenac (Oral Route)

If concurrent use is essential, your doctor may monitor your potassium levels along with your overall treatment and adjust the doses as per the observations.

Frequently asked questions

Breastfeeding women should exercised cautions while on treatment with this medicine. Consult your doctor.
Yes, a study reported that Kerendia 20mg Tablet reduces new-onset of heart failure and improves other heart failure outcomes in patients with chronic kidney disease and type 2 diabetes, irrespective of a history of heart failure or heart disease.
Yes, Kerendia 20mg Tablet may result in hyperkalemia (increased potassium level), especially in patients with reduced kidney function and with already high potassium levels. Your doctor may monitor your potassium level before and during the treatment with Kerendia 20mg Tablet and may adjust its dose accordingly.
Dosing of Kerendia 20mg Tablet is based on estimated glomerular filtration rate (eGFR). eGFR is the amount of waste, in milliliters, your kidneys should be able to filter in a minute. The initial dose of Kerendia 20mg Tablet is 20 mg daily for eGFR of ≥ 60 mL/min and 10 mg daily for eGFR of ≥ 25 to < 60 mL/minute. This medicine is not recommended for patients with eGFR < 25 mL/min. Your doctor may also adjust the dose if you have a high potassium level.
Breastfeeding is not recommended during treatment with this medicine and for 1 day after the treatment.
Yes, Kerendia 20mg Tablet may cause a decrease in blood pressure that can lead to hypotension.

Fact Box

Chemical Class

Dihydropyridine derivative

Habit Forming

No

Therapeutic Class

CARDIAC
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Bayer Zydus Pharma Pvt Ltd
Address: Bayer House, Central Avenue, Hiranandani Estate, Thane (west) Thane 400607 India

Vendor Details

Country of origin: Germany
A licensed vendor partner from your nearest location will deliver Kerendia 20mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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