Lyvelsa 20mg Tablet
Prescription Required
Product introduction
Lyvelsa 20mg Tablet is medicine used in the treatment of chronic kidney disease (CKD) caused by type 2 diabetes (T2D). It works by blocking a certain hormone in the body, which can help prevent the kidneys from getting worse and reduce the risk of heart-related issues like heart attacks and heart failure.
Lyvelsa 20mg Tablet may be taken with or without food. Your doctor will decide the dose and duration of the medicine for you. The doctor may closely monitor your blood pressure, heart rate, electrocardiogram (ECG), estimated glomerular filtration rate (eGFR), urine albumin‐to‐creatinine ratio (UACR), and potassium level till you become stable. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection.
Common side effects of this medicine include high potassium level, low blood pressure, and low sodium level in the body. If you experience any of these side effects, consult your doctor. They may be able to help by reducing the dosage, or by prescribing you an alternate medicine.
This medicine may not be suitable for everybody. Let your doctor know if you are suffering from any kidney or liver disease. Let your doctor also know about all the other medicines you are taking for any medical conditions. Pregnant and breastfeeding women should consult their doctors before taking this medicine.
Uses of Lyvelsa Tablet
Benefits of Lyvelsa Tablet
In Treatment of Chronic kidney disease
Lyvelsa 20mg Tablet is beneficial in reducing the risk of various complications in adults with chronic kidney disease (CKD) linked to type 2 diabetes (T2D). It helps prevent sustained decline in kidney function, progression to end-stage kidney disease, and cardiovascular-related events such as heart attack and heart failure. Additionally, Lyvelsa 20mg Tablet reduces the likelihood of hospitalization due to heart failure and lowers the risk of cardiovascular death. This way it helps manage CKD in diabetic patients, potentially improving both kidney and heart health outcomes.
Side effects of Lyvelsa Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Lyvelsa
- Increased potassium level in blood
- Hypotension (low blood pressure)
- Decreased sodium level in blood
How to use Lyvelsa Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lyvelsa 20mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Lyvelsa Tablet works
Lyvelsa 20mg Tablet is a nonsteroidal, selective antagonist of the mineralocorticoid receptor (MR). This receptor, usually activated by hormones like aldosterone and cortisol, helps in controlling sodium levels in the body. Lyvelsa 20mg Tablet blocks and prevent this receptor from overactivation, which can damage different parts of the body such as the kidneys, heart, and blood vessels.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Lyvelsa 20mg Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Lyvelsa 20mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CAUTION
Lyvelsa 20mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Driving
CONSULT YOUR DOCTOR
It is not known whether Lyvelsa 20mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Lyvelsa 20mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Lyvelsa 20mg Tablet is recommended.
Liver
SAFE IF PRESCRIBED
Lyvelsa 20mg Tablet is safe to use in patients with liver disease. No dose adjustment of Lyvelsa 20mg Tablet is recommended.
What if you forget to take Lyvelsa Tablet?
If you miss a dose of Lyvelsa 20mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Lyvelsa 20mg Tablet
₹94.5/Tablet
Kerendia 20mg Tablet
Bayer Zydus Pharma Pvt Ltd
₹93.86/tablet
1% cheaper
Quick tips
- For patients who are unable to swallow whole tablets, Lyvelsa 20mg Tablet may be crushed and mixed with water or soft foods, before taking it.
- Inform your doctor if you are taking potassium supplements or any other medications for high blood pressure or heart disease.
- Women of childbearing potential should use effective contraception during the treatment to avoid getting pregnant.
- Lyvelsa 20mg Tablet contains lactose; inform your doctor if you have lactose intolerance.
- Lactating women should exercise cautions while on treatment with this medicine.
Fact Box
Habit Forming
No
Therapeutic Class
CARDIAC
Interaction with drugs
Taking Lyvelsa with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Fluconazole may raise blood levels of Finerenone.
Your doctor may monitor your potassium levels along with your overall treatment and adjust the doses as per the observations.
Concurrent use may increase the risk of high blood potassium levels.
If concurrent use is essential, your doctor may monitor your potassium levels along with your overall treatmen
Fluvoxamine may raise blood levels of Finerenone.
Your doctor may monitor your potassium levels along with your overall treatment and adjust the doses as per the observations.
Fosaprepitant may raise blood levels of Finerenone.
Your doctor may monitor your potassium levels along with your overall treatment and adjust the doses as per the observations.
Concurrent use may increase the risk of low blood sodium levels.
If concurrent use is essential, your doctor may monitor your blood sodium levels closely.
Patient concerns
FAQs
Can a breastfeeding women take Lyvelsa 20mg Tablet?
Breastfeeding women should exercised cautions while on treatment with this medicine. Consult your doctor.
Does Lyvelsa 20mg Tablet reduce the risk for heart failure events in high-risk patients?
Yes, a study reported that Lyvelsa 20mg Tablet reduces new-onset of heart failure and improves other heart failure outcomes in patients with chronic kidney disease and type 2 diabetes, irrespective of a history of heart failure or heart disease.
Does Lyvelsa 20mg Tablet increase potassium levels in the body?
Yes, Lyvelsa 20mg Tablet may result in hyperkalemia (increased potassium level), especially in patients with reduced kidney function and with already high potassium levels. Your doctor may monitor your potassium level before and during the treatment with Lyvelsa 20mg Tablet and may adjust its dose accordingly.
What is the dosing frequency of Lyvelsa 20mg Tablet?
Dosing of Lyvelsa 20mg Tablet is based on estimated glomerular filtration rate (eGFR). eGFR is the amount of waste, in milliliters, your kidneys should be able to filter in a minute. The initial dose of Lyvelsa 20mg Tablet is 20 mg daily for eGFR of ≥ 60 mL/min and 10 mg daily for eGFR of ≥ 25 to < 60 mL/minute. This medicine is not recommended for patients with eGFR < 25 mL/min. Your doctor may also adjust the dose if you have a high potassium level.
Can a breastfeeding women take Lyvelsa 20mg Tablet?
Breastfeeding is not recommended during treatment with this medicine and for 1 day after the treatment.
Can Lyvelsa 20mg Tablet result in low blood pressure?
Yes, Lyvelsa 20mg Tablet may cause a decrease in blood pressure that can lead to hypotension.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Finerenone [Prescribing Information]. Whippany, NJ: Bayer HealthCare Pharmaceuticals Inc.; 2021. [Accessed 24 Nov. 2022] (online) Available from:
- Finerenone [Product Monograph]. Mississauga, Ontario: bayer Inc.; 2022. [Accessed 26 June 2023] (online) Available from:
- Central Drugs Standard Control Organization. Finerenone. [Accessed 26 June 2023] (online) Available from:
Marketer details
Name: Sun Pharmaceutical Industries Ltd
Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135
Country of origin: India
Expires on or after: June, 2026
A licensed vendor partner from your nearest location will deliver Lyvelsa 20mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: June, 2026
A licensed vendor partner from your nearest location will deliver Lyvelsa 20mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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