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Bad Obstetric History Panel Advanced

Also referred as
BOH (bad obstetric history) advanced panel
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Bad Obstetric History Panel
Bad Obstetric History (BOH) Profile
Recurrent Pregnancy Loss Panel
For women
Earliest reports in
168 hours
Contains
22 tests
Package price:
₹6299
₹12099
48% off
Get it at ₹5354 with coupon
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The Bad Obstetric History Panel Advanced is a group of blood tests that help identify the causes of repeated miscarriages, stillbirths, or complications in pregnancies. These tests are important for women with a history of pregnancy losses, as they help in planning a healthier future pregnancy.

 

Samples required
Blood
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Why is this package booked?
Preparations
Overnight fasting required for 8 to 12 hours
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Tata 1mg Labs
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TATA 1mg Labs is a cutting-edge facility delivering top-quality diagnostic services right to your doorstep. We take pride in three core values: Assured Quality, Best Prices and Timely Reports. Transparency is at the heart of our operations, ensuring our customers always have clear and reliable information. Our dedicated team is committed to offering an exceptional customer experience and continually innovates to meet and exceed customer expectations.
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Understanding Bad Obstetric History Panel Advanced

Bad Obstetric History (BOH) refers to poor outcomes during pregnancies, including two or more miscarriages, stillbirths, early neonatal death, slow baby growth during pregnancy, or babies born with birth defects. The Bad Obstetric History Panel Advanced helps find the cause of past pregnancy losses and guides treatment to improve the chances of a successful pregnancy.

The BOH panel includes several blood tests to check for infections, immune disorders, and blood clotting problems that can interfere with a healthy pregnancy. It checks for infections like Toxoplasma gondii, Rubella, Cytomegalovirus (CMV), and Herpes Simplex Virus (HSV 1 & 2), collectively known as TORCH infections. These infections can harm a developing baby and may lead to miscarriage or birth defects. These tests can detect past (IgG antibodies) and current (IgM antibodies) infections. The panel also checks for antiphospholipid syndrome (APS), which can cause blood clots in the placenta and lead to miscarriage or preterm birth. Tests like lupus anticoagulants and various antibodies help find clotting disorders. The panel also screens for autoimmune diseases (through anti-nuclear antibodies) and thyroid problems through TSH test that could affect pregnancy.

Doctors may recommend the Bad Obstetric History Panel Advanced for women who have had two or more miscarriages, stillbirths, or pregnancy complications.

For the Bad Obstetric History Panel Advanced, an overnight fast is preferred but is not mandatory. It is advised to stop heparin one day before and oral blood thinners (anticoagulants) seven days before the test, with your doctor’s approval. A filled coagulation form (Annexure - CR/05) is also required at the time of sample collection. It’s also recommended to share your full medical history, current medications, or doctor’s prescription before the test.

Lab test results can be different from one lab to another. If your results are abnormal, it's important to talk to a doctor for proper advice. Never try to treat yourself based on the results alone.

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What does Bad Obstetric History Panel Advanced measure?

Contains 22 tests

The Bad Obstetric History Panel Advanced includes tests that help find the causes of repeated pregnancy losses or complications. It checks for past or current infections like rubella, cytomegalovirus (CMV), herpes simplex virus (HSV 1 & 2), and Toxoplasma gondii by testing antibodies. It also looks for immune system or blood clotting problems, such as antiphospholipid syndrome, which can cause blood clots in the placenta. The panel tests for antibodies like anti-cardiolipin, beta-2 glycoprotein 1, and anti-nuclear antibody (ANA), as well as the lupus anticoagulant profile, to find other autoimmune issues that can hinder the pregnancy. It also includes a thyroid-stimulating hormone (TSH) test to check thyroid function, since thyroid problems can affect pregnancy. Altogether, these tests provide valuable insights into infection history, immune health, blood clotting status, and hormonal balance, which are critical factors for understanding and improving pregnancy outcomes in women with past pregnancy complications.

The Anti Phospholipid Antibody IgM test measures the levels of the immunoglobulin M (IgM) antibodies that bind to phospholipids, essential components of cell membranes. High levels of these antibodies can undoubtedly indicate autoimmune disorders like antiphospholipid syndrome (APS), which increase the risk of thrombotic events and pregnancy complications.Therefore, this test plays a key role in diagnosing APS and assessing the risk of future blood clots. 

Know more about Anti Phospholipid Antibody IgM

A Rubella Virus, IgG test measures the presence of Immunoglobulin G (IgG) antibodies specific to the rubella virus in an individual's blood. IgG antibodies are indicative of previous exposure or vaccination against rubella. This test helps assess an individual’s immunity status to the virus. If the IgG antibodies are detected, it suggests that the individual has either been vaccinated against rubella or has had a previous infection, leading to the development of immune protection. 

Know more about Rubella Virus, IgG

A Rubella Virus, IgM test determines the presence of Immunoglobulin M (IgM) antibodies in the blood against Rubella virus. IgM antibodies are the first line of defense produced by the immune system in response to a recent infection. Therefore, this test is crucial for diagnosing acute or recent rubella infections. 

In acute primary infection during pregnancy, IgM may be detected 4-15 days after the rash appears. The IgM levels begin to decline after 36 -70 days and may last up to 180 days in some cases.

Know more about Rubella Virus, IgM

The Cardiolipin - IgA antibody test detects specific immunoglobulin A (IgA) antibodies against cardiolipin, a phospholipid found in cell membranes. These antibodies can indicate autoimmune disorders such as antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE). IgA is not part of formal APS classification criteria but may be supportive in select cases when Immunoglobulin G (IgG) or Immunoglobulin M (IgM) are negative.

IgA antibodies are part of the immune system's mucosal defense but may also contribute to systemic autoimmune responses. Elevated IgA anticardiolipin antibodies can suggest an ongoing immune reaction, particularly in individuals who may not have detectable IgG or IgM antibodies, providing valuable diagnostic information for autoimmune and thrombotic disorders.

Know more about Cardiolipin - IgA antibody

The HSV 1, IgG & IgM test is a blood test used to measure two types of antibodies: Immunoglobulin G (IgG) and Immunoglobulin M (IgM) against herpes simplex virus (HSV) type 1. IgG antibodies indicate a past infection or long-term presence of the virus, while IgM antibodies suggest a recent or acute infection. By identifying these antibodies, this test helps determine if an individual has been exposed to the virus and distinguishes between new and existing infections.

Getting tested helps in the diagnosis and management of herpes infections. Early and precise identification of HSV infections allows timely medical intervention, reducing symptoms and preventing complications. 

 

Know more about HSV 1, IgG & IgM

This further contains

  • Herpes Simplex Virus 1 IgG
  • Herpes Simplex Virus 1, IgM

A Cytomegalovirus IgG Antibody test measures the presence of IgG antibodies in the blood, indicating a previous CMV infection. IgG antibodies are produced several weeks after the initial CMV infection. IgG levels rise during the active infection, then stabilize as the CMV infection resolves and the virus becomes inactive. Once exposed to CMV, you will have some measurable amount of CMV IgG antibody in your blood for the rest of your life, which provides protection from getting another primary infection (immunity). However, if you have a weak immune system, the virus can reactivate and cause serious symptoms or organ damage.

Know more about Cytomegalovirus IgG Antibody

A Cytomegalovirus IgM Antibody test measures the presence of Immunoglobulin M (IgM) antibodies in the blood, specifically targeting the CMV. IgM antibodies are produced by the body first in response to a CMV infection. They can be detected in the blood within a week or two after the initial exposure. IgM levels rise for a short time, then decline and usually fall below detectable levels after a few months. IgM antibody levels rise again when latent CMV is reactivated.

Elevated levels of CMV IgM antibodies indicate an ongoing infection or recent exposure to the virus. Understanding the presence of IgM antibodies helps doctors diagnose and manage CMV infections effectively. 

 

Know more about Cytomegalovirus IgM Antibody

The Anti Cardiolipin IgM Antibody test detects specific immunoglobulins IgM antibodies against cardiolipin, a phospholipid found in cell membranes. These antibodies can indicate autoimmune disorders such as antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE).

IgM antibodies are typically the first antibodies produced by the immune system in response to an infection or antigen, and the presence of IgM antibodies in the blood sample may suggest recent or acute immune system activation. Thus, the Anti Cardiolipin IgM Antibody test is often used to diagnose acute conditions or recent immune responses, such as recent blood clot formation in disorders like antiphospholipid syndrome (APS).

Know more about Anti Cardiolipin IgM Antibody

The Anti Phospholipid Antibody, IgG test measures the amount of IgG antibodies that target phospholipids, which are important parts of cell membranes. High levels of these antibodies are closely related to autoimmune diseases like antiphospholipid syndrome (APS) and lupus (SLE). These antibodies can raise the risk of blood clots, such as deep vein thrombosis (DVT), pulmonary embolism (PE), stroke, and pregnancy problems like repeated miscarriages and high blood pressure (preeclampsia). This test is crucial for diagnosing these conditions and making treatment decisions for those at risk of blood clots.

Know more about Anti Phospholipid Antibody, IgG

The Beta 2 Glycoprotein 1 IgG Serum test detects the presence of immunoglobulin G (IgG) antibodies against Beta 2 Glycoprotein 1, a protein that plays a crucial role in regulating blood clotting. IgG indicates a chronic or ongoing immune response against β2GPI, which is often associated with an increased risk of blood clotting disorders such as those seen in APS. Elevated levels of these antibodies suggest a higher risk for thrombotic events, such as deep vein thrombosis (DVT), stroke, or miscarriage, particularly when coupled with other clinical factors. By detecting IgG antibodies, this test aids in diagnosing APS and determining the need for medical interventions to manage clotting risk, including anticoagulant therapy or closer monitoring in pregnancy.

Know more about Beta 2 Glycoprotein 1 IgG Serum

The Beta 2 Glycoprotein 1 IgM, Serum test checks for the presence of immunoglobulin M (IgM) antibodies against Beta 2 Glycoprotein 1, a protein that helps regulate blood clotting. IgM antibodies are usually the first type of antibody the body makes in response to new infections or autoimmune issues. Elevated IgM (Immunoglobulin M) levels can indicate an ongoing or recent infection, or they can suggest an autoimmune response. In the context of pregnancy, high IgM levels might be associated with certain conditions like antiphospholipid syndrome or other immune-related issues that could affect pregnancy outcomes. When doctors notice high IgM levels, particularly in pregnant women, it can guide decisions like monitoring the pregnancy more closely for signs of complications, including preterm labor or fetal growth restrictions, considering blood thinners (like heparin or aspirin), especially if the patient is at risk of clotting disorders, which are associated with higher IgM levels in some cases and  checking for infections (e.g., TORCH infections) that could pose risks to the baby.

Know more about Beta 2 Glycoprotein 1 IgM, Serum

The HSV 2, IgG & IgM test is a blood test used to measure two types of antibodies: Immunoglobulin G (IgG) and Immunoglobulin M (IgM) against herpes simplex virus (HSV) type 2. IgG antibodies indicate a past infection or long-term presence of the virus, while IgM antibodies suggest a recent or acute infection. By identifying these antibodies, this test helps determine if an individual has been exposed to the virus and distinguishes between new and existing infections.

Early and precise identification of HSV infections allows timely medical intervention, reducing symptoms and preventing complications. For pregnant women, detecting an HSV infection is crucial to prevent neonatal herpes, which can be severe for newborns. Additionally, knowing one's HSV status helps in taking preventive measures to avoid transmission to sexual partners and others, thus playing a significant role in public health and personal well-being.

Know more about HSV 2, IgG & IgM

This further contains

  • Herpes Simplex Virus 2, IgM
  • Herpes Simplex Virus 2, IgG

The Anti Cardiolipin IgG Antibody test detects specific immunoglobulins IgG antibodies, against cardiolipin, a phospholipid found in cell membranes. These antibodies can indicate autoimmune disorders such as antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE).

IgG antibodies are typically produced by the immune system later in an immune response and remain in the body for a longer time period, suggesting a more chronic or ongoing immune system activation. Therefore, the anticardiolipin IgG test is often used to diagnose chronic conditions or long-term immune responses, such as persistent blood clot formation in disorders like antiphospholipid syndrome (APS).

Know more about Anti Cardiolipin IgG Antibody

An Anti-Nuclear Antibody (ANA) by IFA - End Point Titer test checks for antinuclear antibodies (ANA) in your blood. These antibodies, different from typical ones that fight off invaders in the body, can attach to structures inside the body’s own cell nuclei. If ANAs are present in the blood, it may suggest that your immune system is overly sensitive, causing inflammation against your own tissues and possibly indicating autoimmune diseases. 

Know more about Anti-Nuclear Antibody (ANA) by IFA - End Point Titer

The TSH (Thyroid Stimulating Hormone) Ultrasensitive test measures the levels of TSH hormone in the blood. TSH is produced by the pituitary gland located at the base of the brain. Its function is to stimulate and regulate the functioning of the thyroid gland. It signals the thyroid gland to increase or decrease the production of thyroid hormones T3 and T4 when their levels are low or high, respectively. Therefore, when the levels of T3 & T4 decrease, the pituitary gland is stimulated to release TSH. This high TSH level, in turn, stimulates the thyroid gland to release more thyroid hormones (T3 & T4). It conversely happens when the levels of thyroid hormones increase.

Know more about TSH (Thyroid Stimulating Hormone) Ultrasensitive

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Bad Obstetric History Panel Advanced test price for other cities

Price inGhaziabadRs. 6650
Price inBangaloreRs. 11500
Price inNoidaRs. 6650
Price inLucknowRs. 6650
Price inPuneRs. 11500
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FAQs related to Bad Obstetric History Panel Advanced

The Bad Obstetric History Panel Advanced is a group of blood tests done for women who have had multiple miscarriages, stillbirths, or complications in past pregnancies. It helps find out possible reasons for these unfavorable pregnancy outcomes.
Women who have had two or more miscarriages, stillbirths, or trouble conceiving should take the Bad Obstetric History Panel Advanced.
No, the Bad Obstetric History Panel Advanced is generally safe with minimal risks. You might feel a little discomfort when the blood sample is taken, but serious problems are very rare.
Usually, fasting is preferred but not mandatory for getting tested with a Bad Obstetric History Panel Advanced.
Always discuss your results with a doctor. They will explain what it means and suggest the next steps, treatment, or precautions.
Your doctor will advise you on the frequency of testing based on your medical history and the results of the Bad Obstetric History Panel Advanced.
BOH stands for Bad Obstetric History. It refers to a woman having two or more pregnancy losses or complications in previous pregnancies. This may include miscarriages, stillbirths, early newborn death, birth defects, or other issues like poor baby growth during pregnancy. BOH is a sign that further tests may be needed to find out the cause and plan for a healthier pregnancy in the future.
There could be multiple reasons behind a woman having a bad obstetric history. Some causes may be genetic, while others may be due to thyroid imbalances or due to complications with the uterus or cervix. The best way to identify the exact cause is through proper testing and consultation with a doctor.
Tata 1mg ensures accurate lab test results through certified laboratories that use advanced technology and adhere to stringent quality control measures. This commitment to high standards guarantees reliable results.
Recommended for women
This package is designed with women's health considerations in mind, offering targeted assessments to address unique wellness needs and potential risks.
Package contains 22 tests
Anti Phospholipid Antibody IgM
Rubella Virus, IgG
Rubella Virus, IgM
Cardiolipin - IgA antibody
HSV 1, IgG & IgM (2)
Herpes Simplex Virus 1 IgG
Herpes Simplex Virus 1, IgM
Cytomegalovirus IgG Antibody
Cytomegalovirus IgM Antibody
Lupus Anticoagulant Profile (3)
Activated Partial Thromboplastin Time
Lupus Anticoagulant
DRVV Screen
Toxoplasma gondii, IgG
Toxoplasma gondii, IgM
Anti Cardiolipin IgM Antibody
Anti Phospholipid Antibody, IgG
Beta 2 Glycoprotein 1 IgG Serum
Beta 2 Glycoprotein 1 IgM, Serum
HSV 2, IgG & IgM (2)
Herpes Simplex Virus 2, IgM
Herpes Simplex Virus 2, IgG
Anti Cardiolipin IgG Antibody
Anti-Nuclear Antibody (ANA) by IFA - End Point Titer
TSH (Thyroid Stimulating Hormone) Ultrasensitive
Report delivery
Standard time
168 hrs
For slots after 11 AM, report will be delivered in 168 hours.
Samples required
Blood
Our phlebotomist will draw a blood sample, typically from a vein in your inner elbow.
Preparations
1
Overnight fasting is preferred but not mandatory.
2
With prior consent from the treating physician, it is recommended to discontinue heparin for 1-day and oral anticoagulants for 7-days before sample collection, as these drugs may affect test results.
3
A duly filled coagulation requisition form (Annexure - CR/05) is mandatory for sample collection.
4
Kindly provide complete clinical details and medication history or doctor's prescription; this information is important for correlation of your test results.
5
Do not stop taking your thyroid medications on the day of the test unless otherwise advised by the doctor.
Why is this package booked?
1
In women experiencing consecutive spontaneous abortions.
2
In women who have difficulty conceiving or experience multiple failed pregnancies.
3
In women who have had problems in current or past pregnancies, such as poor baby growth, early baby death, or stillbirth.
4
To detect infections that may harm the fetus or cause miscarriage.
5
To check for autoimmune or blood clotting disorders that can affect pregnancy.
6
To screen for thyroid dysfunction that may interfere with fertility or a healthy pregnancy.
7
To investigate the causes behind previous poor pregnancy outcomes.
8
To guide treatment and preventive care for improving future pregnancy outcomes.
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