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Cytomegalovirus IgG Antibody

Also known as Cytomegalovirus IgG Antibody, Qualitative
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Understanding Cytomegalovirus IgG Antibody

What is Cytomegalovirus IgG Antibody?

A Cytomegalovirus IgG Antibody is a blood test that helps to detect the presence of specific antibodies immunoglobulin G (IgG) produced by the body in response to Cytomegalovirus (CMV). This test helps determine if an individual has been previously exposed to the CMV virus indicating a past infection. 

Cytomegalovirus (CMV) is a common virus that usually causes mild or no symptoms. In some cases, mild illness may present with nonspecific symptoms like sore throat, fever, tiredness, and swollen glands. Occasionally, otherwise healthy individuals may experience flu-like symptoms such as extreme fatigue, fever, chills, body aches, or headaches, usually resolving within a few weeks. Many individuals may not be aware of their CMV infection as it typically does not cause problems in healthy individuals.

CMV infection can pose serious risks to certain populations, such as pregnant women and individuals with weak immune systems. Once infected, the body retains the virus for life without causing any symptoms. After the initial “primary” infection resolves, CMV becomes dormant or latent. However, if your immune system is significantly weakened, the virus can become active again (reactivate) and cause illness.

Cytomegalovirus IgG Antibody test focuses on detecting IgG antibodies, which are immune proteins produced in response to a prior CMV infection. This test is typically advised during pregnancy, especially if there are concerns about congenital abnormalities, unexplained jaundice, or anemia in a newborn, or if an infant has seizures or developmental problems related to CMV. Additionally, the test is recommended for individuals undergoing organ transplants, those with weak immune systems, and when symptoms indicating a potential CMV infection are observed. 

Cytomegalovirus IgG Antibody test is also done as a part of the TORCH panel, a group of tests that screen for several infections that can potentially affect a growing baby during pregnancy.

No special preparation is required before undergoing a Cytomegalovirus IgG Antibody test. However, it is important to inform your doctor about any medications, supplements, or medical conditions before the test as these factors may potentially influence the test results.

Lab test results may vary across different laboratories. Abnormal test results require an expert interpretation; therefore, never try to self-medicate at home based solely on these results, and always consult a doctor for a proper understanding of the test results. The insights from this test help the doctor tailor an appropriate treatment plan.

What is Cytomegalovirus IgG Antibody used for?

A Cytomegalovirus IgG Antibody test is done: 

  • As a part of the TORCH panel to assess the previous exposure to CMV during pregnancy.

  • To monitor CMV reactivation in individuals with weak immune systems. 

  • When symptoms suggestive of CMV infection are present. 

  • If there are concerns about possible congenital CMV infection in newborns.

  • In individuals who may receive an organ transplant.

What does Cytomegalovirus IgG Antibody measure?

A Cytomegalovirus IgG Antibody test measures the presence of IgG antibodies in the blood, indicating a previous CMV infection. IgG antibodies are produced several weeks after the initial CMV infection. IgG levels rise during the active infection, then stabilize as the CMV infection resolves and the virus becomes inactive. Once exposed to CMV, you will have some measurable amount of CMV IgG antibody in your blood for the rest of your life, which provides protection from getting another primary infection (immunity). However, if you have a weak immune system, the virus can reactivate and cause serious symptoms or organ damage.

Answers to Patient Concerns & Frequently Asked Questions (FAQs) about Cytomegalovirus IgG Antibody

Frequently Asked Questions about Cytomegalovirus IgG Antibody

Q. Why might I need a Cytomegalovirus IgG Antibody test?

You may need a {test-name} test if you are experiencing symptoms like fever, fatigue, and muscle aches associated with CMV infection. Additionally, pregnant women may undergo this test to assess the risk of complications for newborns.

Q. How is the Cytomegalovirus IgG Antibody test performed?

The test involves taking a blood sample, usually from a vein in your arm. The blood sample is then sent to a laboratory where it's analyzed for the presence of CMV IgG antibodies.

Q. What if my CMV IgG test result is positive?

If your CMV IgG test result is positive, there is a possibility that you were infected with CMV at some time during your life.

Q. Can you get a CMV infection twice?

Yes, people with weakened immune systems may experience a recurrence or reactivation of CMV or may be infected with a new strain of the virus.

Q. Can the CMV IgG test monitor my treatment for CMV?

No, the CMV IgG test is only used for the diagnosis of previous CMV infection. Your doctor may recommend other tests to monitor your response to treatment.

Q. How is CMV infection transmitted?

CMV is transmitted from an infected person in the following ways: 1) From direct contact with saliva or urine, especially from babies and young children. 2) Through sexual contact. 3) From breast milk to nursing infants. 4) Through transplanted organs and blood transfusions.

Q. How can CMV infection affect a pregnancy?

CMV can be transmitted from a pregnant woman to her unborn child. This can lead to congenital CMV infection.

Q. What birth defects can be caused by CMV infection?

Babies born with CMV infection may face potential long-term health issues, including vision and hearing loss, seizures, spleen, lung, and liver problems, small head size, yellowish skin, and intellectual disability.

Q. Is there a cure for CMV infection?

There is no cure, but there are medications that can help treat and ease the CMV symptoms.
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Cytomegalovirus IgG Antibody test price for other cities

Price inBangaloreRs. 589
Price inKolkataRs. 589
Price inMumbaiRs. 589
Price inGurgaonRs. 589
Price inPuneRs. 589
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  1. About Cytomegalovirus (CMV) [Internet]. CDC; 18 Aug. 2020 [Accessed 09 Feb. 2024]. Available from: https://www.cdc.gov/cmv/overview.html External Link
  2. Cytomegalovirus (Blood) [Internet]. Rochester, NY: University of Rochester Medical Center; [Accessed 09 Feb. 2024]. Available from: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=cytomegalovirus_blood External Link
  3. Gupta M, Shorman M. Cytomegalovirus. [Updated 2023 Aug 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK459185/ External Link
  4. Akpan US, Pillarisetty LS. Congenital Cytomegalovirus Infection. [Updated 2023 Aug 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK541003/ External Link
  5. Munro SC, Hall B, Whybin LR, Leader L, Robertson P, Maine GT, Rawlinson WD. Diagnosis of and screening for cytomegalovirus infection in pregnant women. J Clin Microbiol. 2005 Sep;43(9):4713-8. [Accessed 09 Feb. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1234061/#:~:text=CMV%20IgM%20has%20been%20shown,used%20(11%2C%2043). External Link
  6. Ross SA, Novak Z, Pati S, Boppana SB. Overview of the diagnosis of cytomegalovirus infection. Infect Disord Drug Targets. 2011 Oct;11(5):466-74. [Accessed 09 Feb. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730495/ External Link
  7. Udeze A, Odebisi-Omokanye M, Ajileye T. Cytomegalovirus infection among Human Immunodeficiency Virus (HIV) infected individuals on highly active anti-retroviral therapy in North-Central Nigeria. Afr Health Sci. 2018 Dec;18(4):1057-1065. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354892/ External Link
  8. Prince HE, Lapé-Nixon M. Role of cytomegalovirus (CMV) IgG avidity testing in diagnosing primary CMV infection during pregnancy. Clin Vaccine Immunol. 2014 Oct;21(10):1377-84. [Accessed 09 Feb. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266349/ External Link


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