Zypyra 500 mg Tablet

Prescription Required


Uses of Zypyra Tablet

Zypyra 500 mg Tablet is used in the treatment of tuberculosis.

Zypyra Tablet side effects

  • Jaundice
  • Hepatitis (viral infection of liver)
  • Increased liver enzymes
  • Joint pain

How to use Zypyra Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zypyra 500 mg Tablet is to be taken with food.

How Zypyra Tablet works

Zypyra 500 mg Tablet is an antibiotic. It works by slowing the growth of bacteria that causes tuberculosis.

Zypyra Tablet related warnings

Interaction with alcohol is unknown. Please consult your doctor.
Zypyra 500 mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Zypyra 500 mg Tablet is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
It is not known whether Zypyra 500 mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Zypyra 500 mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Zypyra 500 mg Tablet may be needed. Please consult your doctor.
Kidney function tests are advised before you start taking this medicine.
Zypyra 500 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Zypyra 500 mg Tablet may be needed. Please consult your doctor.
Regular monitoring of liver function tests is advised before and after the start of the treatment.

What if you miss a dose of Zypyra Tablet?

If you miss a dose of Zypyra 500 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Zypyra 500 mg Tablet
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Expert Advice

  • Zypyra 500 mg Tablet along with other medications effectively treats tuberculosis.
  • Do not to forget a dose, as this increases the risk of the bacteria becoming resistant to the medicine, and also increases the risk of getting side effects.
  • Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
  • Avoid drinking alcohol while taking Zypyra 500 mg Tablet as this may increase the risk of side effects on the liver.
  • Use a reliable contraceptive method (such as condoms or a diaphragm) to prevent pregnancy while you are taking Zypyra 500 mg Tablet as it may make hormonal contraceptives such as the pill less effective.

Interaction with Drugs

Taking Zypyra with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Urinol, Zeric, Seloric


Q. What is Zypyra and what is it used for?

Zypyra is an antibiotic. It is used in combination with other antibiotics in the treatment of tuberculosis

Q. Is Zypyra bactericidal?

Zypyra is both a bacteriostatic and a bactericidal antibiotic. It stops the growth of bacteria (bacteriostatic) in certain cases and kills (bactericidal) the tuberculosis causing bacteria in other cases

Q. How does Zypyra work/treat tuberculosis?

Zypyra kills or stops growth of bacteria that causes tuberculosis (Mycobacterium tuberculosis). The exact mechanism of action for Zypyra is not known

Q. How does Zypyra cause hyperuricemia and gout?

Following oral intake of Zypyra, it gets converted in the body to pyrazinoic acid (active chemical form of Zypyra). Pyrazinoic acid blocks the excretion of urates (salt form of uric acid) by the kidneys. This causes an increase in blood levels of uric acid (hyperuricemia). Excess uric acid accumulation between joints causes pain, swelling, redness and stiffness in joints (gout).
Information last updated by Dr. Varun Gupta, MD Pharmacology on 8th Mar 2017.
The medicine details are for information purpose only. Consult a doctor before taking any medicine.
Manufacturer/Marketer Address
Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
We do not facilitate sale of this product at present