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    Pyrazinamide

    Information about Pyrazinamide

    Pyrazinamide uses

    Pyrazinamide is used in the treatment of tuberculosis.

    How pyrazinamide works

    Pyrazinamide is an antibiotic. It works by slowing the growth of bacteria that causes tuberculosis.

    Common side effects of pyrazinamide

    Jaundice, Hepatitis (viral infection of liver), Increased liver enzymes, Joint pain

    Available Medicine for Pyrazinamide

    • ₹40 to ₹90
      Lupin Ltd
      4 variant(s)
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      Cadila Pharmaceuticals Ltd
      3 variant(s)
    • ₹23 to ₹84
      Macleods Pharmaceuticals Pvt Ltd
      5 variant(s)
    • ₹60 to ₹64
      Novartis India Ltd
      2 variant(s)
    • ₹76
      Concept Pharmaceuticals Ltd
      1 variant(s)
    • ₹39 to ₹62
      Sunij Pharma Pvt Ltd
      2 variant(s)
    • ₹54
      Que Pharma Pvt Ltd
      1 variant(s)
    • ₹18
      Cadila Pharmaceuticals Ltd
      1 variant(s)
    • ₹17 to ₹112
      Kopran Ltd
      3 variant(s)
    • ₹48 to ₹94
      Overseas Healthcare Pvt Ltd
      3 variant(s)

    Expert advice for Pyrazinamide

    • Your doctor has prescribed Pyrazinamide to cure your infection and improve symptoms.
    • You can take it with food or on an empty stomach.
    • Pyrazinamide may cause a rash after sun exposure; hence avoid sun exposure.
    • Tell your doctor immediately if you experience skin rash, severe itching or hives, pain or swelling in the joints, yellowing of the skin or eyes or dark urine, weakness, nausea or vomiting, loss of appetite.

    Frequently asked questions for Pyrazinamide

    Pyrazinamide

    Q. What is Pyrazinamide and what is it used for?

    Pyrazinamide is an antibiotic. It is used in combination with other antibiotics in the treatment of tuberculosis

    Q. Is Pyrazinamide bactericidal?

    Pyrazinamide is both a bacteriostatic and a bactericidal antibiotic. It stops the growth of bacteria (bacteriostatic) in certain cases and kills (bactericidal) the tuberculosis causing bacteria in other cases

    Q. How does Pyrazinamide work/treat tuberculosis?

    Pyrazinamide kills or stops growth of bacteria that causes tuberculosis (Mycobacterium tuberculosis). The exact mechanism of action for Pyrazinamide is not known

    Q. How does Pyrazinamide cause hyperuricemia and gout?

    Following oral intake of Pyrazinamide, it gets converted in the body to pyrazinoic acid (active chemical form of Pyrazinamide). Pyrazinoic acid blocks the excretion of urates (salt form of uric acid) by the kidneys. This causes an increase in blood levels of uric acid (hyperuricemia). Excess uric acid accumulation between joints causes pain, swelling, redness and stiffness in joints (gout).

    Content on this page was last updated on 16 April, 2018, by Dr. Varun Gupta (MD Pharmacology)