Pyrazinamide

Information about Pyrazinamide

Pyrazinamide Uses

Pyrazinamide is used in the treatment of tuberculosis.

How Pyrazinamide works

Pyrazinamide is an antitubercular medicine. In the body, it gets converted to pyrazinoic acid. This pyrazinoic acid inhibits fatty acid synthase I (bacterial enzyme), which is essential for bacterial growth. Thus, it works as a bacteriocidal to prohibit their growth and treats tuberculosis.

Common side effects of Pyrazinamide

Hepatitis (viral infection of liver), Joint pain, Nausea, Vomiting, Abdominal pain
CONTENT DETAILS
Written By
BDS
Reviewed By
MD (Pharmacology), MBBS
Last updated
26 Aug 2022 | 10:13 PM (UTC)

We provide you with authentic, trustworthy and revelant information

Want to know more

Available Medicine for Pyrazinamide

PyzinaLupin Ltd
51 to ₹1104 variant(s)
P ZideCadila Pharmaceuticals Ltd
45 to ₹964 variant(s)
MacrozideMacleods Pharmaceuticals Pvt Ltd
26 to ₹1105 variant(s)
Pza CibaNovartis India Ltd
10 to ₹735 variant(s)
MzideMarc Laboratories Pvt Ltd
49 to ₹803 variant(s)
PyraKopran Ltd
17 to ₹1113 variant(s)
TicimideThemis Medicare Ltd
40 to ₹642 variant(s)
PyranijSunij Pharma Pvt Ltd
39 to ₹612 variant(s)
PyramidQue Pharma Pvt Ltd
54 to ₹572 variant(s)
AnzideAan Pharma Pvt Ltd
501 variant(s)

Expert advice for Pyrazinamide

  • Pyrazinamide along with other medications effectively treats tuberculosis.
  • Do not to forget a dose, as this increases the risk of the bacteria becoming resistant to the medicine, and also increases the risk of getting side effects.
  • Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
  • Avoid drinking alcohol while taking Pyrazinamide as this may increase the risk of side effects on the liver.
  • Use a reliable contraceptive method (such as condoms or a diaphragm) to prevent pregnancy while you are taking Pyrazinamide as it may make hormonal contraceptives such as the pill less effective.

Frequently asked questions for Pyrazinamide

Pyrazinamide

Q. What is Pyrazinamide and what is it used for?

Pyrazinamide is an antibiotic. It is used in combination with other antibiotics in the treatment of tuberculosis

Q. Is Pyrazinamide bactericidal?

Pyrazinamide is both a bacteriostatic and a bactericidal antibiotic. It stops the growth of bacteria (bacteriostatic) in certain cases and kills (bactericidal) the tuberculosis causing bacteria in other cases

Q. How does Pyrazinamide work/treat tuberculosis?

Pyrazinamide kills or stops growth of bacteria that causes tuberculosis (Mycobacterium tuberculosis). The exact mechanism of action for Pyrazinamide is not known

Q. How does Pyrazinamide cause hyperuricemia and gout?

Following oral intake of Pyrazinamide, it gets converted in the body to pyrazinoic acid (active chemical form of Pyrazinamide). Pyrazinoic acid blocks the excretion of urates (salt form of uric acid) by the kidneys. This causes an increase in blood levels of uric acid (hyperuricemia). Excess uric acid accumulation between joints causes pain, swelling, redness and stiffness in joints (gout).

INDIA’S LARGEST HEALTHCARE PLATFORM

260m+
Visitors
31m+
Orders Delivered
1800+
Cities
Get the link to download App
Reliable

All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

LegitScript approved
India's only LegitScript and ISO/ IEC 27001 certified online healthcare platform

Know more about Tata 1mgdownArrow

Access medical and health information

Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.