Zonisep 25 Capsule

Prescription Required
SALT COMPOSITION
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Store below 30°C
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Product introduction

Zonisep 25 Capsule is an anti-epileptic medicine used to treat seizures in epilepsy. It can be used by itself to treat adults or along with other medicines to treat adults and children. It helps to prevent seizures affecting a part or whole of the brain.

Zonisep 25 Capsule suppresses the abnormal electrical activity in the brain. You can take it with or without food but try to take it at the same time each day to get the most benefit. The dose will depend on your condition and how you respond to the medicine. Your doctor will advise the right dose for you.

You should continue taking it for as long as your doctor has told you to, even if you feel well. If you stop or miss doses your seizures could get worse. It may take several months to come off it safely. It is advised not to change the brand of medication without doctor consultation, and always keep a stock of medicine with you.

Very few people taking it have any serious problems but the most common side effects of this medicine include dizziness, loss of appetite, memory loss, drowsiness, and impaired concentration. You may also experience altered walking, impaired coordination, and unusual anger. Side effects are more common during the first few weeks and usually lessen as your body gets used to the medicine. Most do not need medical attention, but some of them can be serious. Let your doctor know if you have any symptoms as there may be ways of preventing or reducing them.

A small number of people being treated with this medicine have had thoughts of harming or killing themselves. Contact your doctor if your mood changes for the worse. Please do not take this medicine if you are allergic to sulfa medicines.

Before taking it, you should tell your doctor if you have kidney problems, depression or suicidal thoughts and if you are pregnant or planning to become pregnant. You should not breastfeed while taking this medicine. Alcohol may increase the risk of seizures and worsen the side effects such as drowsiness and dizziness. Avoid alcohol while taking this medicine. Drowsiness and dizziness may affect your ability to drive or operate machinery. Your kidney function may need to be tested often while taking this medicine.

Uses of Zonisep Capsule

Benefits of Zonisep Capsule

In Epilepsy/Seizures

Zonisep 25 Capsule slows down electrical signals in the brain which cause seizures (fits). It can also help reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety. The medicine can allow you to do some activities that you would otherwise be forbidden or scared to do (such as swimming and driving). It can take a few weeks for this medicine to work (because the dose has to be increased slowly) and during this time you may still have seizures. Do not stop using this medicine even if you feel well, until your doctor advises you to. Missing doses may trigger a seizure.

Side effects of Zonisep Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zonisep

  • Dizziness
  • Loss of appetite
  • Memory impairment
  • Drowsiness
  • Impaired concentration
  • Altered walking
  • Impaired coordination
  • Anger

How to use Zonisep Capsule

Take this medicine in the dose and duration as advised by your doctor. Zonisep 25 Capsule may be taken with or without food, but it is better to take it at a fixed time.

How Zonisep Capsule works

Zonisep 25 Capsule is an antiepileptic medication. It prevents seizures in patients with epilepsy by suppressing the abnormal and excessive activity of the nerve cells in the brain.

Safety advice

Alcohol
UNSAFE
Zonisep 25 Capsule may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Zonisep 25 Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Zonisep 25 Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Zonisep 25 Capsule may cause side effects which could affect your ability to drive.
As Zonisep 25 Capsule may affect your concentration, ability to react/respond, and may make you feel sleepy, particularly at the beginning of your treatment or after your dose is increased.
Kidney
CAUTION
Zonisep 25 Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Zonisep 25 Capsule may be needed. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Zonisep 25 Capsule in patients with liver disease. Please consult your doctor.
Use of Zonisep 25 Capsule is not recommended in patients with severe liver disease.

What if you forget to take Zonisep Capsule?

If you miss a dose of Zonisep 25 Capsule, skip it and continue with your normal schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
  • Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
  • Some healthy tips to prevent seizures:
    • Take a healthy diet along with regular exercise.
    • Practice yoga every day.
    • Get enough sleep at nighttime.
    • Limit the use of screen time such as mobile/ laptop.
    • Take your medication on time.
  • Do not drive or do anything that requires mental focus until you know how this medicine affects you.
  • Drink plenty of water while taking Zonisep 25 Capsule to reduce the risk of kidney stones and heat stroke. Inform your doctor if you have sudden pain in your stomach, pain on urinating, or if you find blood in your urine.
  • It may cause loss of appetite and weight. Monitor your weight regularly.
  • Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
  • Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.

Fact Box

Chemical Class
Benzisoxazole & Sulfonamide Derivatives
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Brain carbonic anhydrase inhibitors

Interaction with drugs

Taking Zonisep with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Antep, C Lep, Ametol
Moderate
Brand(s): Milorgen, Fosphen, Fosentin
Moderate
Brand(s): Shinosun, Epikon, Sonal
Moderate
Brand(s): Stoin
Moderate

Patient concerns

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Rolandic epilepsy. Treated with zonisep. Doctor tells after some age it will disappear. Pl clarrify
Dr. Gopal Bansilal Samdani
Paediatrics
Please consult child neurologist
She has problem of epilepsy from last two years
Dr. Rahul Yadav
Paediatrics
Hello, epilepsy and seizures cannot be treated online without physically examining the child and detailed history.
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User feedback


FAQs

Q. What happens if I stop taking Zonisep 25 Capsule?

Do not stop taking Zonisep 25 Capsule without talking to your doctor. Stopping Zonisep 25 Capsule suddenly may cause serious problems, including seizures that will not stop.

Q. My friend, who was on Zonisep 25 Capsule, developed severe muscle pain with fever. What could this be due to?

Severe muscle pain or weakness, with or without fever, could be due to Zonisep 25 Capsule. Consult your doctor immediately. The doctor may suggest some blood tests to check your levels of serum creatine phosphokinase and aldolase enzymes. Elevated levels of these enzymes may prompt the doctor to discontinue Zonisep 25 Capsule.

Q. What are the effects of Zonisep 25 Capsule in children?

Zonisep 25 Capsule works well in children and is well tolerated by most of them. The common side effects in children include problems with thinking or behavior, followed by stomach upset. One dangerous side effect of Zonisep 25 Capsule in children is decreased sweating with fever. This affects children but not adults and is more common in summers.

Q. I have been taking Zonisep 25 Capsule for epilepsy since a month, but now I feel that my life has come to an end and sometimes I want to harm myself. Is it because of the medicine? What should I do?

Though uncommon, Zonisep 25 Capsule may increase the risk of suicidal thoughts or behavior. Sometimes, it can also be due to the disease itself. You should immediately consult your doctor who will consider discontinuing Zonisep 25 Capsule. We recommend that you take the help of your friend or relative to go to the hospital.

Q. Does Zonisep 25 Capsule cause weight loss?

Yes, Zonisep 25 Capsule may cause weight loss. If you lose weight, consult a dietician for dietary supplement or try to increase your food portions. In case you lose a lot of weight, consider discontinuing Zonisep 25 Capsule after consulting your doctor. Weight loss may be more serious in children, so be cautious and keep monitoring the weight.

Q. Does Zonisep 25 Capsule affect the working of birth control pills?

No, Zonisep 25 Capsule does not interfere with the working of birth control pills.

Q. Does Zonisep 25 Capsule have any effect on kidneys?

Yes, if you are at a risk of developing kidney stones, taking Zonisep 25 Capsule may increase that risk. Stones can lead to further kidney damage. The symptoms of kidney stones include severe sharp pain in lower abdomen or back pain. Increase your fluid intake which can reduce the risk of kidney stones. Consult your doctor if you get any such symptoms.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Stahl SM, editor. Zonisamide. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 755-58.
  2. McNamara JO. Pharmacotherapy of the Epilepsies. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 602.
  3. Porters RJ, Meldrum BS. Antiseizure Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 412.
  4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1520-21.
  5. Zonisamide [FDA Label]. St. Michael, Barbados: Concordia Pharmaceuticals Inc.2015 [Revised April 2016]. [Accessed 19 Mar. 2019] (online) Available from:External Link
  6. Zonisamide [Package Leaflet]. Hatfield, UK: Eisai Manufacturing Ltd.; 2018. [Accessed 17 Jun. 2019] (online) Available from:External Link
  7. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Zonisamide. [Updated 2020 Jan 20]. [Accessed 20 Feb. 2020] (online) Available from:External Link
  8. Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:External Link
  9. Zonisamide [Product Information]. Ahmedabad, India: Zydus Lifesciences Ltd.; 2022. [Accessed 07 Aug. 2023]. (online) Available from:External Link

Marketer details

Name: Sun Pharmaceutical Industries Ltd
Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135
Country of origin: India
Expires on or after: July, 2025

A licensed vendor partner from your nearest location will deliver Zonisep 25 Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

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