Zonegran Tablet

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Overview

Introduction

Zonegran Tablet is an anti-epileptic medicine used to treat seizures in epilepsy. It can be used by itself to treat adults or along with other medicines to treat adults and children. It helps to prevent seizures affecting a part or whole of the brain.

Zonegran Tablet suppresses the abnormal electrical activity in the brain. You can take it with or without food but try to take it at the same time each day to get the most benefit. The dose will depend on your condition and how you respond to the medicine. Your doctor will advise the right dose for you.

You should continue taking it for as long as your doctor has told you to, even if you feel well. If you stop or miss doses your seizures could get worse. It may take several months to come off it safely. It is advised not to change the brand of medication without doctor consultation, and always keep a stock of medicine with you.

Very few people taking it have any serious problems but the most common side effects of this medicine include dizziness, loss of appetite, memory loss, drowsiness, and impaired concentration. You may also experience altered walking, impaired coordination, and unusual anger. Side effects are more common during the first few weeks and usually lessen as your body gets used to the medicine. Most do not need medical attention, but some of them can be serious. Let your doctor know if you have any symptoms as there may be ways of preventing or reducing them.

A small number of people being treated with this medicine have had thoughts of harming or killing themselves. Contact your doctor if your mood changes for the worse. Please do not take this medicine if you are allergic to sulfa medicines.

Before taking it, you should tell your doctor if you have kidney problems, depression or suicidal thoughts and if you are pregnant or planning to become pregnant. You should not breastfeed while taking this medicine. Alcohol may increase the risk of seizures and worsen the side effects such as drowsiness and dizziness. Avoid alcohol while taking this medicine. Drowsiness and dizziness may affect your ability to drive or operate machinery. Your kidney function may need to be tested often while taking this medicine.

Uses of Zonegran Tablet

Side effects of Zonegran Tablet

Common
  • Dizziness
  • Loss of appetite
  • Memory impairment
  • Drowsiness
  • Impaired concentration
  • Altered walking
  • Coordination impaired
  • Anger

How to use Zonegran Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zonegran Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Zonegran Tablet works

Zonegran Tablet is an antiepileptic medication. It prevents seizures in patients with epilepsy by suppressing the abnormal and excessive activity of the nerve cells in the brain.

Safety Advice

Alcohol
UNSAFE
Zonegran Tablet may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Zonegran Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Zonegran Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Zonegran Tablet may cause side effects which could affect your ability to drive.
As Zonegran Tablet may affect your concentration, ability to react/respond, and may make you feel sleepy, particularly at the beginning of your treatment or after your dose is increased.
Kidney
CAUTION
Zonegran Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Zonegran Tablet may be needed. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Zonegran Tablet in patients with liver disease. Please consult your doctor.
Use of Zonegran Tablet is not recommended in patients with severe liver disease.

What if you forget to take Zonegran Tablet?

If you miss a dose of Zonegran Tablet, skip it and continue with your normal schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
No alternate brands found for this medicine

Quick Tips

  • Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
  • Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
  • Some healthy tips to prevent seizures:
    • Take a healthy diet along with regular exercise.
    • Practice yoga every day.
    • Get enough sleep at nighttime.
    • Limit the use of screen time such as mobile/ laptop.
    • Take your medication on time.
  • Do not drive or do anything that requires mental focus until you know how this medicine affects you.
  • Drink plenty of water while taking Zonegran Tablet to reduce the risk of kidney stones and heat stroke. Inform your doctor if you have sudden pain in your stomach, pain on urinating, or if you find blood in your urine.
  • It may cause loss of appetite and weight. Monitor your weight regularly.
  • Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
  • Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.

Interaction with Drugs

Taking Zonegran with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Antep, C Lep, Ametol
MODERATE
Brand(s): Milorgen, Fosphen, Fosentin
MODERATE
Brand(s): Shinosun, Epikon, Pheosol
MODERATE
Brand(s): Stoin
MODERATE

Patient Concerns

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I m using zonegran frm last 6 yrs now smetmes i hve headache and more sleepness
Dr. Jyoti Kapoor Madan
Psychiatry
Sleep problems are often caused by underlying physical and/ or psychological cause. This requires examination of the patient so that proper treatment can be initiated. Often stress/ anxiety/ depression or mood disorder needs to be dealt with and sleeping pills are not adequate treatment. Please go through the link below - http://drjyotikapoor.com/2015/01/26/sleep-disorders/
She has problem of epilepsy from last two years
Dr. Rahul Yadav
Paediatrics
Hello, epilepsy and seizures cannot be treated online without physically examining the child and detailed history.
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Do you have any questions related to Zonegran Tablet ?

User Feedback


FAQs

Q. What happens if I stop taking Zonegran?

Do not stop taking Zonegran without talking to your doctor. Stopping Zonegran suddenly may cause serious problems, including seizures that will not stop.

Q. My friend, who was on Zonegran, developed severe muscle pain with fever. What could this be due to?

Severe muscle pain or weakness, with or without fever, could be due to Zonegran. Consult your doctor immediately. The doctor may suggest some blood tests to check your levels of serum creatine phosphokinase and aldolase enzymes. Elevated levels of these enzymes may prompt the doctor to discontinue Zonegran.

Q. What are the effects of Zonegran in children?

Zonegran works well in children and is well tolerated by most of them. The common side effects in children include problems with thinking or behavior, followed by stomach upset. One dangerous side effect of Zonegran in children is decreased sweating with fever. This affects children but not adults and is more common in summers.

Q. I have been taking Zonegran for epilepsy since a month, but now I feel that my life has come to an end and sometimes I want to harm myself. Is it because of the medicine? What should I do?

Though uncommon, Zonegran may increase the risk of suicidal thoughts or behavior. Sometimes, it can also be due to the disease itself. You should immediately consult your doctor who will consider discontinuing Zonegran. We recommend that you take the help of your friend or relative to go to the hospital.

Q. Does Zonegran cause weight loss?

Yes, Zonegran may cause weight loss. If you lose weight, consult a dietician for dietary supplement or try to increase your food portions. In case you lose a lot of weight, consider discontinuing Zonegran after consulting your doctor. Weight loss may be more serious in children, so be cautious and keep monitoring the weight.

Q. Does Zonegran affect the working of birth control pills?

No, Zonegran does not interfere with the working of birth control pills.

Q. Does Zonegran have any effect on kidneys?

Yes, if you are at a risk of developing kidney stones, taking Zonegran may increase that risk. Stones can lead to further kidney damage. The symptoms of kidney stones include severe sharp pain in lower abdomen or back pain. Increase your fluid intake which can reduce the risk of kidney stones. Consult your doctor if you get any such symptoms.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Stahl SM, editor. Zonisamide. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 755-58.
  2. McNamara JO. Pharmacotherapy of the Epilepsies. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 602.
  3. Porters RJ, Meldrum BS. Antiseizure Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 412.
  4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1520-21.
  5. Zonisamide. St. Michael, Barbados: Concordia Pharmaceuticals Inc.2015 [Revised April 2016]. [Accessed 19 Mar. 2019] (online) Available from:External Link
  6. Zonisamide. Hatfield, UK: Eisai Manufacturing Ltd.; 2018. [Accessed 17 Jun. 2019] (online) Available from:External Link
  7. U.S. National Library of Medicine. Zonisamide. [Accessed 19 Mar. 2019] (online) Available from:External Link
  8. Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
1st Floor, B Wing,Marwah Centre, Krishanlal Marwah Marg, Andheri ( East ), Mumbai - 400072, India
A licensed pharmacy from your nearest location will deliver Zonegran Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
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₹166.4
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