Zoladex LA 10.8mg Injection

Prescription Required
Manufacturer
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.

Introduction

Zoladex LA 10.8mg Injection is used for the treatment of prostate cancer in men.

Zoladex LA 10.8mg Injection is given as an injection under the skin by a qualified medical professional.  Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Hot flashes are a very common side effect of this medicine. It may also cause injection site reactions such as pain, swelling, and redness. The long-term use of medicine may cause weakened bones and a reduction in bone mineral density. You are advised to take vitamin D and calcium supplements while taking this medicine.

Before taking this medicine, inform your doctor if you have a history of drinking alcohol and diabetes. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Zoladex Injection

Benefits of Zoladex Injection

In Prostate cancer

Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Zoladex LA 10.8mg Injection decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.

Side effects of Zoladex Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zoladex

  • Hot flashes
  • Bone weakness
  • Injection site reactions (pain, swelling, redness)

How to use Zoladex Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Zoladex Injection works

Zoladex LA 10.8mg Injection is a synthetic hormone. It works by reducing the level of testosterone (male hormone). This causes regression of prostate tumor and improves symptoms.

Safety advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Zoladex LA 10.8mg Injection. Please consult your doctor.
Pregnancy
UNSAFE
Zoladex LA 10.8mg Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
UNSAFE
Zoladex LA 10.8mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
SAFE
Zoladex LA 10.8mg Injection does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Zoladex LA 10.8mg Injection is safe to use in patients with kidney disease. No dose adjustment of Zoladex LA 10.8mg Injection is recommended.
Liver
SAFE IF PRESCRIBED
Zoladex LA 10.8mg Injection is safe to use in patients with liver disease. No dose adjustment of Zoladex LA 10.8mg Injection is recommended.

What if you forget to take Zoladex Injection?

If you miss a dose of Zoladex LA 10.8mg Injection, please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No alternate brands found for this medicine

Quick tips

  • Zoladex LA 10.8mg Injection is used in the treatment of prostate cancer.
  • It is a prefilled syringe that is injected under the skin of the abdomen, every 12 weeks.
  • It should not be used in females and children.
  • It may cause a reduction in bone mineral density and weakened bones. Your doctor may prescribe other medicines to reduce bone loss.
  • Inform your doctor if you start to feel depressed or have disturbing thoughts or feelings during treatment with this medicine.
  • Inform your doctor if you suffer from high blood pressure or irregular heartbeat.

Fact Box

Chemical Class
GNRH Analogue
Habit Forming
No
Therapeutic Class
HORMONES
Action Class
GNRH agonists/analogue

Patient concerns

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My Dr. has given dose of inj. Zoladex 3.6 mg for endometriosis, 3 doses of its are compulsory or 2 doses are sufficient, because I have some side effects like sleeping problem, headache and sickness. Please suggest me.
Dr. Megha Tuli
Obstetrics and Gynaecology
Zoladex is a hormonal treatment. Please cpntinue as prescribed.
I have problem of frequent urination at night. My father had same at his time.Doctor told me that I am having BPH.Also I went through PSA whose result is 1.8 increased prostate gland size is 40 which came in ultrasound report .When doctor did some test by inserting his finger in my rectal area I felt abnormal pain.doctor asked me to go for a culture test so as to check which can be the best medicine for BPH for me. Kindly suggest if it can be something else like prostate cancer.
Dr. Vijay Sharnangat
Medical Oncology and Hematology
May not be prostate cancer, it is only begnin enlargement of prostate.
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User feedback


FAQs

Q. Is Zoladex LA 10.8mg Injection chemotherapy?

Zoladex LA 10.8mg Injection is a chemotherapeutic agent used in the treatment of hormone-sensitive cancers of the breast (in pre- and peri- menopausal women) and prostate, and some benign gynecological disorders (endometriosis, uterine fibroids and endometrial thinning). In addition, it is used in assisted reproduction and in the treatment of precocious puberty

Q. What is Zoladex LA 10.8mg Injection implant?

Zoladex LA 10.8mg Injection implants contain the active ingredient Zoladex LA 10.8mg Injection acetate and are injected under the surface of the skin on the stomach

Q. How long can I take zoladex for?

It is given once or multiple times as required. Please consult your doctor before taking the drug

Q. Can I take paracetamol/ibuprofen/noethisterone with zoladex?

Yes you can take paracetamol/ibuprofen/noethisterone with zoladex.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Goserelin acetate. Luton, Bedfordshire: AstraZeneca UK Limited; 2001 [revised 24 Jan. 2017]. [Accessed 26 Mar. 2019] (online) Available from:External Link
  2. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link
  3. UpToDate. Goserelin: Drug information. [Accessed 25 Jun. 2019] (online) Available from:External Link
  4. OncoLink. Goserelin Acetate. [Accessed 25 Jun. 2019] (online) Available from:External Link

Manufacturer/Marketer address

Corporate & Registered Office, Block N1, 12th Floor, Manyata Embassy Business Park, Rachenahalli, Outer Ring Road, 560045, Bangalore
Country of origin: India

Expires on or after: December, 2021

A licensed vendor partner from your nearest location will deliver Zoladex LA 10.8mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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1 Injection in 1 prefilled syringe
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