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Composition FOR ZIN OD

Pyrazinamide(NA)

food interaction for ZIN OD

alcohol interaction for ZIN OD

pregnancy interaction for ZIN OD

lactation interaction for ZIN OD

medicine interaction for ZIN OD

food
alcohol
pregnancy
lactation
medicine
It is better to take Zin od tablet with food.
Interaction with alcohol is unknown. Please consult your doctor.
Zin od tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
WEIGH RISKS VS. BENEFITS
Zin od tablet is probably safe to use during breastfeeding. Please consult your doctor.
SAFE
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  • SALT INFORMATION FOR ZIN OD

    Pyrazinamide(NA)

    Uses

    Zin od tablet is used in the treatment of headache, dental pain, osteoarthritis, muscle pain (myalgia), joint pain (arthralgia), rheumatic fever, rheumatoid arthritis, post operative pain and fever

    How it works

    Zin od tablet is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause fever, pain, swelling, and blood clots.

    Common side effects

    Reduced blood platelets, Joint pain, Increased sensitivity to light, Vomiting, Abnormal liver function tests, Bleeding disorder, Nausea, Loss of appetite, Dyspepsia, Jaundice, Anemia, Gastrointestinal irritation, Blood in urine, Skin rash, Gastric erosion, Gastritis, Nose bleed, Difficulty in urination, Gastric ulcer

    SUBSTITUTES FOR ZIN OD

    No substitutes found

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    Expert advice FOR ZIN OD

    • Avoid alcoholic beverages while taking this drug.
    • Do not have any immunizations/vaccinations while using this medication without the consent of your doctor.
    • Contact your doctor immediately if you experience symptoms such as persistent nausea,  vomiting, feeling of discomfort (malaise) or jaundice (abnormal liver function causing yellowing of skin and eyes) while taking pyrazinamide. It indicates that you are developing liver disease.
    • Constant monitoring of liver function (especially levels of enzymes aspartate transferase [AST] and alanine transferase [ALT]) and blood uric acid levels is advised while on treatment with pyrazinamide.
    • Do consult your doctor before taking pyrazinamide if you are pregnant or planning to become pregnant.
    • Do not use pyrazinamide, if you are breast-feeding.
    • Do not stop taking pyrazinamide without consulting your doctor.
    • If you forget to take a dose of pyrazinamide, take it as soon as you remember. Do not double the dose to make up for the missed dose.
    • Do consult your doctor if you are taking oral contraceptive medications (hormonal birth control pills) for birth control. Your doctor may ask you to use other means of birth control (eg. condom, diaphragm with spermicide) to prevent pregnancy while taking pyrazinamide.

    Frequently asked questions FOR ZIN OD

    Pyrazinamide

    Q.

    What is pyrazinamide and what is it used for?
    Pyrazinamide is an antibiotic. It is used in combination with other antibiotics in the treatment of tuberculosis

    Q.

    Is pyrazinamide bactericidal?
    Pyrazinamide is both a bacteriostatic and a bactericidal antibiotic. It stops the growth of bacteria (bacteriostatic) in certain cases and kills (bactericidal) the tuberculosis causing bacteria in other cases

    Q.

    How does pyrazinamide work/treat tuberculosis?
    Pyrazinamide kills or stops growth of bacteria that causes tuberculosis (Mycobacterium tuberculosis). The exact mechanism of action for pyrazinamide is not known

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    Q.

    How does pyrazinamide cause hyperuricemia and gout?
    Following oral intake of pyrazinamide, it gets converted in the body to pyrazinoic acid (active chemical form of pyrazinamide). Pyrazinoic acid blocks the excretion of urates (salt form of uric acid) by the kidneys. This causes an increase in blood levels of uric acid (hyperuricemia). Excess uric acid accumulation between joints causes pain, swelling, redness and stiffness in joints (gout).

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    Content on this page was last updated on 08 March, 2017, by Dr. Varun Gupta (MD Pharmacology)