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Ziddivir 100mg Tablet

Zidovudine (100mg)
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Ziddivir 100mg Tablet belongs to a group of medicines called antiretrovirals. It is used to treat HIV (human immunodeficiency virus), the virus that can cause AIDS (acquired immunodeficiency syndrome). It helps to control HIV infection so your immune system can work better.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 Nov 2025 | 03:05 PM (IST)
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General Information

The content is shown in English
Ziddivir 100mg Tablet image
Ziddivir 100mg Tablet image

Product introduction

Ziddivir 100mg Tablet is not a cure for HIV or AIDS and only helps to decrease the amount of HIV in your body. This helps to lower your risk of getting HIV-related complications and improves your lifespan. It is prescribed in combination with other HIV medicines. Your doctor will recommend the best medicines for you and will decide the doses that you need. Follow carefully the instructions for all the medicines that you are given. It can be taken with or without food. Taking all these medicines regularly at the right times greatly increases their effectiveness and reduces the chances of HIV becoming resistant to them. It is important not to miss doses and to keep taking them until your doctor tells you it is safe to stop.

Common side effects of this medicine include headache, nausea, vomiting, stomach pain, fatigue, diarrhea, and rash. These are usually not serious but tell your doctor if they bother you or will not go away. Rarely, some people may experience a skin reaction or liver damage. Your doctor will closely monitor you for these in the initial period of treatment.

Before taking it, tell your doctor if you have any skin problems or liver or kidney disease. While using it, you may need regular blood tests to check your blood counts and liver function. Avoid drinking alcohol as it may increase your risk of liver damage. Pregnant or breastfeeding mothers should consult their doctor before using this medicine. Do not have unprotected sex or share personal items like razors or toothbrushes, if you are HIV positive. Talk to your doctor about safe ways like condoms to prevent HIV transmission during sex.

Uses of Ziddivir Tablet

Benefits of Ziddivir Tablet

HIV infection
Ziddivir 100mg Tablet reduces the amount of virus in the body, which helps protect and strengthen the immune system. By preventing the virus from replicating, it slows the progression of HIV, lowers the risk of complications, and improves overall health. When used as part of combination antiretroviral therapy (ART), Ziddivir 100mg Tablet helps manage the infection, enhancing the patient’s quality of life and reducing the risk of HIV-related conditions. It also plays a key role in preventing mother-to-child transmission of HIV during pregnancy.

Side effects of Ziddivir Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Ziddivir
  • Rash
  • Headache
  • Decreased appetite
  • Nausea
  • Vomiting
  • Fever
  • General discomfort
  • Decreased white blood cell count (neutrophils)
  • Anemia (low number of red blood cells)
  • Cough

How to use Ziddivir Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ziddivir 100mg Tablet may be taken with or without food.

How Ziddivir Tablet works

Ziddivir 100mg Tablet is an antiviral medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.

All substitutes for Ziddivir 100mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • In combination with other medicines, it is used for the treatment of HIV infections.
  • Take it with food, as this increases the absorption of the medicine into the body.
  • Ziddivir 100mg Tablet may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • You may still develop infections or other illnesses associated with viral infection while taking this medication.
  • You can also pass on HIV or HBV to others. Don't share needles or personal items that can have blood or body fluids on them.
  • During treatment and for at least six months after stopping this medicine, regular blood tests are needed to monitor your liver function, level of hepatitis B virus and blood cells in your blood.
  • You have been prescribed Ziddivir 100mg Tablet for the treatment of chronic hepatitis B virus (HBV) infection.
  • In combination with other medicines, it is used for the treatment of HIV infections.
  • Take it with food, as this increases the absorption of the medicine into the body.
  • Ziddivir 100mg Tablet may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • You may still develop infections or other illnesses associated with viral infection while taking this medication.
  • You can also pass on HIV or HBV to others. Don't share needles or personal items that can have blood or body fluids on them.
  • During treatment and for at least six months after stopping this medicine, regular blood tests are needed to monitor your liver function, level of hepatitis B virus and blood cells in your blood.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Ziddivir 100mg Tablet.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Ziddivir 100mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Ziddivir 100mg Tablet may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Driving

Driving

UNSAFE
Ziddivir 100mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Ziddivir 100mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Ziddivir 100mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Ziddivir 100mg Tablet is not recommended in patients with moderate to severe liver disease.

Interaction with drugs

Taking Ziddivir with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Amphotericin B (Injection Route)

Your doctor may monitor your blood cell count for toxicity of medicines and adjust the doses as per the observations.
Severe

Amphotericin B (Vaginal Route)

Your doctor may monitor your blood cell count for toxicity of medicines and adjust the doses as per the observations.
Severe

Sodium Valproate (Oral Route)

Watch out for symptoms such as fatigue, weakness, abnormal bleeding, mouth ulcers, numbness, impaired coordination, or body aches, and consult your doctor if you experience them.
Severe

Sodium Valproate (Injection Route)

Watch out for symptoms such as fatigue, weakness, abnormal bleeding, mouth ulcers, numbness, impaired coordination, or body aches, and consult your doctor if you experience them.
Severe

Stavudine (Oral Route)

Do not consume Stavudine with Zidovudine. If concurrent use is essential, please consult your doctor. Zidovudine may block the action of Stavudine.

Frequently asked questions

Ziddivir 100mg Tablet belongs to a group of medicines called antiretrovirals. It is used to treat HIV (human immunodeficiency virus), the virus that can cause AIDS (acquired immunodeficiency syndrome). It helps to control HIV infection so your immune system can work better.
Ziddivir 100mg Tablet is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
Ziddivir 100mg Tablet works by blocking the function of an enzyme, called reverse transcriptase, which is responsible for the HIV replication process. This helps to reduce the level of HIV in the blood.
Ziddivir 100mg Tablet should be taken in the dose and duration advised by the doctor. This medicine may be taken with or without food but it is better to be taken at a fixed time of the day to avoid the chances of missing a dose.
Ziddivir 100mg Tablet is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Ziddivir 100mg Tablet too early, the symptoms may return or worsen.
If you forget a dose of Ziddivir 100mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.

Fact Box

Chemical Class

Pyrimidine 2',3'- dideoxyribonucleosides

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Action Class

Nucleoside/Nucleotide Reverse Transcriptase Inhibitors (NRTIs)

References

  1. Flexner C. Antiretroviral Agents and Treatment of HIV Infection. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1632-633.
  2. Safrin S. Antiviral Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 860-61.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1506-514.
  4. Zidovudine. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2008 [revised 12 Nov. 2018]. [Accessed 31 Mar. 2019] (online) Available from:
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 31 Mar. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Sain Medicaments Pvt Ltd
Address: 10, H.V.E.S, Building Complex, Kandaswamy Lane, Sultan Bazar Hyderabad-500029, Andhra Pradesh, India

Vendor Details

Country of origin: India
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