Zaxaglit 5mg Tablet is a medicine used to treat type 2 diabetes mellitus. It is used together with a healthy diet and regular exercise to control blood sugar levels. This helps to prevent serious complications of diabetes like kidney damage and blindness.

You should take it regularly, at the same time each day, to get the most benefit and you should not stop unless your doctor recommends it. It is controlling your blood sugar levels and helping to prevent serious complications in the future. It is important to stay on the diet and exercise program recommended by your doctor while taking this medicine. Your lifestyle plays a big part in controlling diabetes.

The most common side effect of taking this medicine is a headache. This is usually minor and improves with time. Low blood sugar level (hypoglycemia) is a possible side effect if you are also taking other diabetes medicines like insulin or sulphonylurea, so you need to know how to recognize and deal with it. It may also cause upper respiratory tract infections like sore throat, cough, and cold. Contact your doctor if the side effects worry you or if they do not go away.

Before taking this medicine, let your doctor know if you have ever had kidney disease, heart or pancreas problems, or if you drink a lot of alcohol. Pregnant or breastfeeding women should also consult their doctor before taking it. Some other medicines you are taking may interfere with it so make sure your doctor knows about all the other medicines you are using. Limit your alcohol intake while taking this medicine because it can increase your risk of developing low blood sugar levels. You may need regular tests such as kidney function and blood glucose levels to check that the medicine is working properly.

Uses of Zaxaglit Tablet

Type 2 diabetes mellitus

Side effects of Zaxaglit Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zaxaglit

Hypoglycaemia (low blood sugar level) in combination with insulin or sulphonylurea
Upper respiratory tract infection
Urinary tract infection
Headache
Peripheral edema

How to use Zaxaglit Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zaxaglit 5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Zaxaglit Tablet works

Zaxaglit 5mg Tablet is an antidiabetic medication. It works by increasing the release of insulin from the pancreas and decreasing the hormones that raise blood sugar levels. This reduces the fasting and postmeal sugar levels.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Zaxaglit 5mg Tablet.

Pregnancy

SAFE IF PRESCRIBED

Zaxaglit 5mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

CONSULT YOUR DOCTOR

Zaxaglit 5mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

CAUTION

Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.

Kidney

CAUTION

Zaxaglit 5mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Zaxaglit 5mg Tablet may be needed. Please consult your doctor.
Regular monitoring of kidney function tests is recommended for dose adjustment.

Liver

SAFE IF PRESCRIBED

Zaxaglit 5mg Tablet is safe to use in patients with liver disease. No dose adjustment of Zaxaglit 5mg Tablet is recommended.

What if you forget to take Zaxaglit Tablet?

If you miss a dose of Zaxaglit 5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Zaxaglit 5mg Tablet

₹41.9/Tablet

Onglyza 5mg Tablet

AstraZeneca

₹45.79/tablet

9% costlier

Riax 5mg Tablet

Dr Reddy's Laboratories Ltd

₹41.93/tablet

same price

Zaglivia 5mg Tablet

Hauz Pharma Pvt Ltd

₹41.7/tablet

same price

Saglipol 5 Tablet

Medipol Pharmaceuticals India Pvt Ltd

₹57.2/tablet

37% costlier

Saxaquest 5mg Tablet

Morepen Laboratories Ltd

₹18.2/tablet

57% cheaper

Quick tips

Zaxaglit 5mg Tablet should be taken at the same time every day since this helps you remember to take it.
Be careful while driving or operating machinery until you know how Zaxaglit 5mg Tablet affects you.
It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremor and anxiety.
Inform your doctor if you notice joint pains or develop symptoms such as stomach pain, nausea and/or vomiting.

Fact Box

Chemical Class

Alpha amino acid amides

Habit Forming

Therapeutic Class

ANTI DIABETIC

Action Class

Dipeptidyl Peptidase-4 (DPP-4) Inhibitors

Interaction with drugs

Taking Zaxaglit with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Disopyramide (Oral Route) Severe

Concurrent use may increase the risk of low blood sugar levels. Elderly, malnourished, diabetic individuals and those with kidney and heart dysfunction are at higher risk. If conc... More

Amisulpride (Injection Route) Moderate

Amisulpride may reduce the efficacy of Saxagliptin. If concurrent use is essential, your doctor may monitor your glucose levels frequently and adjust the doses as per the observat... More

Amisulpride (Oral Route) Moderate

Amisulpride may reduce the efficacy of Saxagliptin. If concurrent use is essential, your doctor may monitor your glucose levels frequently and adjust the doses as per the observat... More

Aripiprazole (Oral Route) Moderate

Aripiprazole may reduce the efficacy of Saxagliptin. If concurrent use is essential, your doctor may monitor your glucose levels frequently and adjust the doses as per the observa... More

Asparaginase (Oral Route) Moderate

Concurrent use may interfere with control over blood sugar. Your doctor may monitor your diabetic control closely and adjust the doses as per the observations.

View all drug interactions

Patient concerns

Diabetes mellitus type 2 ,thirst

Dr. Sanjay Bhatt

Physician

A person can control his or her sugar levels by doing regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOUR DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but a start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications like kidney or heart problems .online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

Diabetes mellitus type 2 required only ayurvedic medicine

Dr. Sanjay Bhatt

Physician

Go for allopathic medicine

Any latest discoveris for type 1 mellitus Diabetes?

Dr. Sanjay Bhatt

Physician

Diabetes Ireland is delighted to hear of the Harvard success and congratulate Professor Melton and colleagues on figuring out the complex series of steps necessary to turn stem cells into beta cells. Hopefully, they can negotiate the regulations for mass production so that an abundant supply of beta cells is available an new and innovative methods will be developed to cure/treat Type 1 diabetes. Type I diabetes is an autoimmune condition whereby the body kills off its own beta (insulin producing) cells resulting in the need for daily insulin administration through the skin. Replacing beta cells in the first step towards a cure, but the replaced beta cells need to be protected from the body?s autoimmune response. This means protecting them in a coating or taking drugs to prevent the response (possible worse side effects than diabetes).

How to manage diabetes mellitus

Dr. Sanjay Bhatt

Physician

A person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND LOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you souls not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

FAQs

Does Zaxaglit 5mg Tablet cause any weight loss (reduction)?

No, Zaxaglit 5mg Tablet neither causes weight loss nor weight gain. It is weight neutral. However, weight gain can be seen when Zaxaglit 5mg Tablet is used with other antidiabetic medicines like thiazolidinediones, sulfonylureas or insulin.

What is the benefit of using Zaxaglit 5mg Tablet with insulin?

Zaxaglit 5mg Tablet when taken with insulin can help in lowering the insulin dose and decrease the risk of hypoglycemia (low blood sugar levels). Consult your doctor as a dose adjustment of the two may be needed.

Are there any contraindications to the use of Zaxaglit 5mg Tablet?

Yes, the use of Zaxaglit 5mg Tablet is contraindicated in some conditions like a history of allergy to Zaxaglit 5mg Tablet, any ingredients of this drug or to any other drug of the same class. Zaxaglit 5mg Tablet should also be avoided in patients with a history of pancreatitis.

Is it beneficial to use Zaxaglit 5mg Tablet with glipizide?

Yes, it is beneficial to take Zaxaglit 5mg Tablet and glipizide. Both are antidiabetic drugs, however, they work in different ways. When taken together, they can help in better controlling of blood sugar levels.

Can Zaxaglit 5mg Tablet be used with other diabetes medicines?

Yes, Zaxaglit 5mg Tablet can be used alone or in combination with other diabetes medicines, along with proper diet and exercise.

Can the use of Zaxaglit 5mg Tablet cause hypoglycemia (low blood sugar)?

Usually, Zaxaglit 5mg Tablet does not cause hypoglycemia when used alone in diabetes. However, it may cause low blood sugar when combined with other medicines like insulin and sulfonylureas.

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Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1264.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1248-49.
Saxagliptin. Princeton, New Jersey: Bristol-Myers Squibb Company; 2009. [Accessed 12 Mar. 2019] (online) Available from:
Saxagliptin. Macclesfield, Cheshire: AstraZeneca UK Limited; 2018. [Accessed 12 Mar. 2019] (online) Available from:
Saxagliptin [Summary of Product Characteristics]. Södertälje, Sweden; AstraZeneca AB. [Accessed 09 Feb. 2022] (online) Available from:
Saxagliptin [FDA Prescribing Information]. Wilmington, DE; AstraZeneca Pharmaceuticals LP; 2015. [Accessed 09 Feb. 2022] (online) Available from:
Saxagliptin [EMC Label]. Luton, UK; AstraZeneca UK Limited; 2021. [Accessed 09 Feb. 2022] (online) Available from:
Saxagliptin [Prescribing Informataion]. Princeton, NJ: Bristol-Myers Squibb Company; 2009. [Accessed 20 Feb. 2024] (online) Available from:

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