Zapsign 10 Capsule

Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS

Last updated on 25 Nov 2025 | 03:05 PM (IST)

Zapsign 10 Capsule is used to treat insomnia. It reduces sleep onset time and frequent awakening at night. This medicine improves sleep maintenance and therefore ensures sound sleep.

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General Information

Contains

Zaleplon (10mg)

Marketer

HAB Pharma

Storage

Store below 30°C

The content is shown in English

Product introduction

Zapsign 10 Capsule should be taken on an empty stomach, preferably before going to bed. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor as it is habit-forming. Do not stop taking it suddenly without talking to your doctor as it may worsen your symptoms.

Some common side effects of this medicine include lightheadedness, impaired coordination, and tingling sensation. However, these are temporary and resolve on their own after some time. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you and do not take alcohol with it as it may worsen the dizziness. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, hallucinations, or suicidal thoughts while taking this medicine.

Before taking Zapsign 10 Capsule, inform your doctor about all other medicines that you are taking, so that your doctor can advise if taking this medicine is right for you. Consult your doctor before taking this medicine if you are suffering from any liver or kidney problems. You should avoid smoking and alcohol while using this medicine. Pregnant and breastfeeding mothers should not use this medicine. However, if the need arises, please consult your doctor before using it.

Uses of Zapsign Capsule

Insomnia

Benefits of Zapsign Capsule

Insomnia
Zapsign 10 Capsule is used to treat insomnia by helping people fall asleep faster. It supports better sleep onset without causing grogginess the next day, making it useful for those who have trouble falling asleep but not necessarily staying asleep.

Side effects of Zapsign Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zapsign

Dizziness
Lightheadedness
Impaired coordination
Paresthesia (tingling or pricking sensation)

How to use Zapsign Capsule

Take this medicine in the dose and duration as advised by your doctor. Zapsign 10 Capsule is to be taken on an empty stomach.

How Zapsign Capsule works

Zapsign 10 Capsule is a nonbenzodiazepine hypnotic. Along with sedative, it may also have anxiolytic (panic-reducing or antianxiety), muscle relaxant properties. It works by binding GABA-A/chloride ion channel receptor complex (receptor), thus relaxes the nerves and brain. This is how it helps you to fall asleep.

Quick tips

Your doctor has prescribed Zapsign 10 Capsule to help you fall asleep faster and sleep for longer.
It is best taken without food as a high-fat meal can reduce its absorption and effect.
Take it 30 to 45 minutes before bedtime and only when you have time to sleep for at least 7 hours.
It makes you feel dizzy next morning. Don't drive or do anything requiring concentration until you know how it affects you.
It does not affect total sleep time. However, it reduces sleep onset time and frequent awakening at night.
Never share your medication with any other person who also has a sleep problem.
Inform your doctor if your sleep doesn’t improve after 7 to 10 days of treatment.
Stop taking medication and inform your doctor If you experience sleep driving or memory loss.
Do not stop taking medication suddenly as it may lead to anxiety, mood changes, and restlessness.
Your doctor has prescribed Zapsign 10 Capsule to help you fall asleep faster and sleep for longer.
It is best taken without food as a high-fat meal can reduce its absorption and effect.
Take it 30 to 45 minutes before bedtime and only when you have time to sleep for at least 7 hours.
It makes you feel dizzy next morning. Don't drive or do anything requiring concentration until you know how it affects you.
It does not affect total sleep time. However, it reduces sleep onset time and frequent awakening at night.
Never share your medication with any other person who also has a sleep problem.
Inform your doctor if your sleep doesn’t improve after 7 to 10 days of treatment.
Stop taking medication and inform your doctor If you experience sleep driving or memory loss.
Inform your doctor if you are on depression medication while starting treatment with Zapsign 10 Capsule.
Do not stop taking medication suddenly as it may lead to anxiety, mood changes, and restlessness.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Zapsign 10 Capsule

Pregnancy

CONSULT YOUR DOCTOR

The safety of Zapsign 10 Capsule during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

SAFE IF PRESCRIBED

Zapsign 10 Capsule may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Driving

UNSAFE

Zapsign 10 Capsule may cause side effects that could affect your ability to drive.

Kidney

CAUTION

Zapsign 10 Capsule should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Limited information is available on the use of Zapsign 10 Capsule in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.

Liver

CAUTION

Zapsign 10 Capsule should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Zapsign 10 Capsule is not recommended in patients with severe liver disease.

Interaction with drugs

Taking Zapsign with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Tramadol (Injection Route)

If concurrent use is essential, watch out for symptoms of Zaleplon side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Zaleplon as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.

Severe

Tramadol (Oral Route)

Severe

Morphine (Oral Route)

Severe

Codeine (Oral Route)

Severe

Buprenorphine (Injection Route)

Frequently asked questions

Does Zapsign 10 Capsule have abuse potential?

Yes, Zapsign 10 Capsule has abuse potential. However, it is more commonly seen in patients with a history of drug abuse, alcohol consumption, and drug addiction. Therefore, doctors should carefully take history of drug abuse from the patient. Moreover, patients with a history of drug abuse or addiction should be closely monitored during Zapsign 10 Capsule therapy.

What are the symptoms of an overdose of Zapsign 10 Capsule?

The symptoms of Zapsign 10 Capsule overdose include drowsiness, confusion, problems with coordination, floppy muscles, slow or difficult breathing, and even coma (loss of consciousness for a period of time).

What should I should avoid when taking Zapsign 10 Capsule?

Zapsign 10 Capsule can make you drowsy during the daytime and also decrease your mental alertness. Therefore, you should not drive or operate heavy machinery until and unless you know how Zapsign 10 Capsule affects you. Do not drink alcohol while you are taking Zapsign 10 Capsule. Alcohol can make the side effects of Zapsign 10 Capsule even worse.

Who should not take Zapsign 10 Capsule?

You should not take Zapsign 10 Capsule if you are allergic to it or any of its ingredients. You should also avoid Zapsign 10 Capsule if you have a history of depression, mental illness, or suicidal thoughts. A person having a history of drug or alcohol abuse or addiction, having kidney or liver disease, having a lung disease or breathing problems should avoid Zapsign 10 Capsule. Also, its consumption is not recommended if you are pregnant, planning to become pregnant, or breastfeeding.

Can I take Zapsign 10 Capsule with food?

No, do not take Zapsign 10 Capsule with or shortly after a heavy, high-fat meal. Zapsign 10 Capsule may not work well if it is taken with high-fat foods.

Can Zapsign 10 Capsule be taken everyday? How long should it be taken?

Zapsign 10 Capsule is used for short-term (2-4 weeks) treatment of insomnia (difficulty falling asleep). It should be taken exactly as prescribed by the doctor. The dose and duration of treatment should not be exceeded else it may lead to dependence (addiction towards medicine).

Does Zapsign 10 Capsule cause dry mouth and affect weight?

Yes, dry mouth is a common side effect of Zapsign 10 Capsule, whereas weight gain is less common with Zapsign 10 Capsule. If you experience weight gain, it could be due to increased appetite.

How long does Zapsign 10 Capsule take to start working?

Zapsign 10 Capsule starts working as soon as you take it and may make you very sleepy. You may remain sleepy for some time after you take the medication. Plan to go to bed right after you take Zapsign 10 Capsule and to stay in bed for 7 to 8 hours. Do not take Zapsign 10 Capsule if you will be unable to go to bed right away.

What are the withdrawal symptoms of Zapsign 10 Capsule?

Do not stop taking Zapsign 10 Capsule without talking to your doctor. If you suddenly stop taking Zapsign 10 Capsule, you may experience withdrawal symptoms such as unpleasant feelings, stomach and muscle cramps, vomiting, sweating, shakiness, and rarely, seizures.

How can I improve my sleep without medicines?

You can improve your sleep by avoiding caffeine and nicotine, especially late in the day. Avoid exercise during the four hours before bedtime; daily exercise is beneficial to sleep, but can interfere if done close to bedtime. Avoid large meals in the evening. Avoid taking naps. Go to sleep and wake up at the same time each day. Keep the bedroom as dark as possible and maintain a comfortable temperature. Set aside a time to relax before bed and use relaxation techniques.

What is insomnia?

Insomnia is a common sleep disorder. People with insomnia experience trouble in falling asleep, staying asleep, or both. As a result, they may get too little sleep or have poor-quality sleep, and they may not feel refreshed after waking up.

What are the causes of insomnia?

Insomnia can be of two types- primary or secondary. In primary insomnia, the cause is not known. It can be triggered by life-style changes including long-lasting stress and emotional upset. Whereas, secondary insomnia can be caused due to various reasons such as certain medical conditions (depression, anxiety, post-traumatic stress disorder, Alzheimer's disease, and Parkinson's disease), medicines, sleep disorders, and substances (caffeine and other stimulants, tobacco and other nicotine products, and alcohol).

Fact Box

Chemical Class

Phenylpyrimidines

Habit Forming

Yes

Therapeutic Class

NEURO CNS

Action Class

Non-Benzodiazepine Hypnotics (Z-Drugs)

References

Stahl SM, editor. Zaleplon. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 739-41.
Mihic SJ, Harris RA. Hypnotics and Sedatives. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 467.
Trevor AJ, Way WL. Sedative-Hypnotic Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 381.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1503-504.
Zalepon. Sellersville, PA: TEVA PHARMACEUTICALS USA; 2008. [Accessed 19 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Zaleplon. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: HAB Pharma
Address: 308, T.V. Industrial Estate, S.K. Ahire Marg, Behind Glaxo Lab, Worli, Mumbai 400 030

Vendor Details

Country of origin: India

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Zapsign 10 Capsule

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Zapsign Capsule

Benefits of Zapsign Capsule

Side effects of Zapsign Capsule

How to use Zapsign Capsule

How Zapsign Capsule works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Tramadol (Injection Route)

Tramadol (Oral Route)

Morphine (Oral Route)

Codeine (Oral Route)

Buprenorphine (Injection Route)

Frequently asked questions

Does Zapsign 10 Capsule have abuse potential?

What are the symptoms of an overdose of Zapsign 10 Capsule?

What should I should avoid when taking Zapsign 10 Capsule?

Who should not take Zapsign 10 Capsule?

Can I take Zapsign 10 Capsule with food?

Can Zapsign 10 Capsule be taken everyday? How long should it be taken?

Does Zapsign 10 Capsule cause dry mouth and affect weight?

How long does Zapsign 10 Capsule take to start working?

What are the withdrawal symptoms of Zapsign 10 Capsule?

How can I improve my sleep without medicines?

What is insomnia?

What are the causes of insomnia?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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