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Venlor-XR 37.5 Capsule

Prescription Required



Venlor-XR 37.5 Capsule is a prescription medicine used in the treatment of depression and anxiety disorder. It alters the chemicals in the brain that cause symptoms of anxiety such as irritability, restlessness, lack of concentration, fatigue, sweating, increased heart rate and unwanted or racing thoughts.

Venlor-XR 37.5 Capsule should be taken with food. It is advised to take this medicine at a fixed time each day to maintain a consistent level in the blood. If you miss any doses, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly as it may worsen your symptoms.

Some common side effects of this medicine include nausea, vomiting, insomnia (difficulty in sleeping), decreased appetite, anxiety, constipation, increased sweating, and sexual dysfunction. It may cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. However, these side effects are temporary and usually resolve on their own in some time. Please consult your doctor if these do not subside or bother you.

Before taking Venlor-XR 37.5 Capsule, inform your doctor if you have any problems with your kidneys, heart, liver, or have a history of seizures (epilepsy or fits). Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or if you have any suicidal thoughts.

Uses of Venlor Capsule PR

Side effects of Venlor Capsule PR

  • Nausea
  • Vomiting
  • Dizziness
  • Insomnia (difficulty in sleeping)
  • Decreased appetite
  • Anxiety
  • Constipation
  • Increased sweating
  • Sexual dysfunction

How to use Venlor Capsule PR

Use it as advised by your doctor or check the label for directions before use. Venlor-XR 37.5 Capsule is to be taken with food.

How Venlor Capsule PR works

Venlor-XR 37.5 Capsule works by increasing the levels of chemical messengers (serotonin and noradrenaline), natural substances in the brain that help maintain mental balance.

Safety Advice

It is unsafe to consume alcohol with Venlor-XR 37.5 Capsule.
Venlor-XR 37.5 Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Venlor-XR 37.5 Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Babies should be monitored for excessive sleepiness and adequate weight gain.
Venlor-XR 37.5 Capsule may cause side effects which could affect your ability to drive.
As side effects of Venlor-XR 37.5 Capsule are dizziness, confusion and eye sight changes such as blurred vision and this may affect your ability to drive.
Venlor-XR 37.5 Capsule should be used with caution in patients with kidney disease. Dose adjustment of Venlor-XR 37.5 Capsule may be needed. Please consult your doctor.
Venlor-XR 37.5 Capsule should be used with caution in patients with liver disease. Dose adjustment of Venlor-XR 37.5 Capsule may be needed. Please consult your doctor.

What if you forget to take Venlor Capsule PR?

If you miss a dose of Venlor-XR 37.5 Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Venlor-XR 37.5 Capsule
₹4.96/Capsule PR
Venlift OD 37.5 Capsule PR
Torrent Pharmaceuticals Ltd
₹4.58/Capsule PR
save 8%

Quick Tips

  • Venlor-XR 37.5 Capsule helps in treating depression and anxiety.
  • It may also  be used to treat nerve pain from diabetes and some other forms of chronic pain.
  • It may take 2 to 4 weeks for Venlor-XR 37.5 Capsule to start working. Keep taking it as prescribed.
  • It may cause dizziness and sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • Avoid consuming alcohol when taking Venlor-XR 37.5 Capsule as it may cause excessive drowsiness and increase the risk of liver damage.
  • It may cause a sensation of restlessness, especially when you first start taking it. Inform your doctor if this happens to you.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
  • Do not stop taking the medication suddenly without talking to your doctor.

Interaction with Drugs

Taking Venlor with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Lizolan, Lidoford, Mapzolide
Brand(s): Trima, Rimarex, Morex
Brand(s): Rasalect, Relgin, Rasipar
Brand(s): Jumex

Patient Concerns

Self taking venlor xr 75 - one per day since last 10 years. Is there any possibility to stop this. If yes. What precaution to be taken
Dr. Jyoti Kapoor Madan
Based in your clinical history, your doctor plans the type of medicine and it's dose and duration. For first episode of anxiety/ depression/ panic, the usual maintenance phase is 6 months of asymptomatic period, after which medicines can be gradually tapered. But treatment may need to continue longer depending on severity and frequency of episodes. To take any decision to change medication or stop them, several factors have to be taken in account for which regular follow up with your psychiatrist is important. For second opinion, seek a proper consultation with another psychiatrist and take along your previous prescriptions. If you just want to stop, reduce to 37.5mg for a few weeks, then stop.
I am having problem in eating. the food just dosen't taste to me . I have depression & taking Venlor 75MG & Arip 10 MG tablets regularly
Dr. Sfurti Mann
Internal Medicine
Take tab pantop before breakfast for two weeks Get a upper GI endoscopy done
Do you have any questions related to Venlor-XR 37.5 Capsule ?

User Feedback


Q. Can Venlor cause sedation?

Yes. Venlor can cause sedation. You should inform your doctor if you are taking any other sleep inducing medicines before starting Venlor.

Q. Is Venlor a psychotropic drug?

Yes. Venlor is a psychotropic drug. Any medication capable of affecting the mind, emotions, and behaviour are called psychotropic drugs.

Q. Is Venlor a narcotic?

No. Venlor is not a narcotic drug. Narcotics are drugs with sleep inducing properties, usual derivatives of Opium like Heroin and Morphine.

Q. What is the difference between Venlor ER and XR?

Both are same medication. Venlor ER and XR both means extended release preparation which releases the medication slowly into the body and maintains a constant needed medications levels. The advantage of taking ER/XR tablets is the frequency of dosage can be decreased.

Q. Can I take mirtazapine along with Venlor?

No. There can be a serious side effect when mirtazapine is taken with Venlor. It can cause a serious condition called as serotonin syndrome. It is a potentially life-threatening can present as agitation, hallucinations, nausea, vomiting, diarrhoea, tachycardia, labile blood pressure, hyperthermia and coma.

Q. Can I take Venlor with citalopram?

No. Citalopram and Venlor both increase serotonin levels. Avoid or use any alternate drug. It can cause a serious condition called as serotonin syndrome. It is a potentially life-threatening can present as agitation, hallucinations, nausea, vomiting, diarrhoea, tachycardia, labile blood pressure, hyperthermia and coma.

Q. What is the relation between Venlor and p-glycoprotein?

P-glycoprotein is responsible for the expulsion of Venlor from the brain. Some studies have shown that Venlor and its metabolite inhibit the p-glycoprotein.

Q. Where is Venlor absorbed?

Venlor is absorbed from the intestine after being metabolised by the liver.

Q. When should I take Venlor?

Venlor is a medication to treat generalised depressive disorder or depression. Consult your doctor before taking this medication.

Q. Can Venlor cause high blood pressure?

Venlor treatment is associated with sustained increases in blood pressure in some people. It is recommended that people who are being treated with Venlor should have regular monitoring of blood pressure. For such people, either dose reduction or discontinuation should be considered.

Q. Can Venlor cause constipation?

Yes. Venlor is known to cause constipation in some patients. Take a fiber-rich diet and drink plenty of water. You may consider taking laxatives as well. Your doctor will suggest ways to prevent or manage it. Please consult your doctor if it does not resolve or gets worse.

Q. Can Venlor cause weight loss?

Yes. Venlor is known to cause weight loss in some patients. In research studies, a dose-dependent weight loss was noted in patients treated with Venlor for several weeks. Please consult your doctor if it bothers you.

Q. Can Venlor cause addiction?

No. Venlor does not have habit-forming potential.

Q. Can I take Venlor tablet instead of a capsule?

You can take a tablet instead of the capsule but only under consultation or prescription of a doctor. You should not change it yourself as the different formulation of a medication may have a different action as drug release would be different in both. This can lead to an inappropriate treatment and may lead to side effects or even failure of treatment.

Q. Can gabapentin be given along with Venlor?

Yes. Gabapentin can be given with Venlor but only with a consultation of a doctor. They both, when given together, causes an increase drowsiness, sleepiness and decreased concentration in work. Take with caution.

Q. What is the difference between Venlor and desvenlafaxine?

Desvenlafaxine is an active metabolite of Venlor. It is the same medication in an active form.

Q. Can fibromyalgia be treated with Venlor?

Venlor is not approved for the treatment of fibromyalgia. Some research studies have shown promising results of Venlor in the treatment of fibromyalgia. Consult your doctor before starting this medication.

Q. Can nerve pain be treated with Venlor?

Venlor is not approved for treatment of nerve pain disorders but some researchers have proved its efficacy in nerve pain. It is currently used off-label for nerve pain.

Q. Why does Venlor cause loss of appetite?

Venlor is known to cause changes in the neurotransmitters levels and chemicals in the brain which leads to decrease in appetite and this loss of appetite is dose dependent.

Q. What are good alternatives to Venlor, particularly when a side effect is reduced sex drive?

If you find any side effects like decreased sex drive or impotence talk to your doctor and then you can have some other drug. Do not stop Venlor by yourself it can lead to increased adverse effects.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
  1. Stahl SM, editor. Venlafaxine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 721-26.
  2. DeBattista C. Antidepressant Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 513.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1466.
  4. Venlafaxine.Marietta, USA:Kremers Urban Pharmaceuticals Inc.;1993[revised 06-2014]. [Accessed 19 Mar. 2019] (online) Available from:External Link
  5. U.S. National Library of Medicine. Venlafaxine. [Accessed 19 Mar. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:External Link
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