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Venlift OD 37.5 Capsule PR

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Overview

Introduction

Venlift OD 37.5 Capsule PR is a prescription medicine used in the treatment of depression and anxiety disorder. It alters the chemicals in the brain that cause symptoms of anxiety such as irritability, restlessness, lack of concentration, fatigue, sweating, increased heart rate and unwanted or racing thoughts.

Venlift OD 37.5 Capsule PR should be taken with food. It is advised to take this medicine at a fixed time each day to maintain a consistent level in the blood. If you miss any doses, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly as it may worsen your symptoms.

Some common side effects of this medicine include nausea, vomiting, insomnia (difficulty in sleeping), decreased appetite, anxiety, constipation, increased sweating, and sexual dysfunction. It may cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. However, these side effects are temporary and usually resolve on their own in some time. Please consult your doctor if these do not subside or bother you.

Before taking Venlift OD 37.5 Capsule PR, inform your doctor if you have any problems with your kidneys, heart, liver, or have a history of seizures (epilepsy or fits). Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or if you have any suicidal thoughts.

Uses of Venlift Capsule PR

Side effects of Venlift Capsule PR

Common
  • Nausea
  • Vomiting
  • Dizziness
  • Insomnia (difficulty in sleeping)
  • Decreased appetite
  • Anxiety
  • Constipation
  • Increased sweating
  • Sexual dysfunction

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Nausea
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop from feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Vomiting
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Dizziness
    This is usually short-lived and should go away within a few days. If this happens, stop what you are doing and sit or lie down until you feel better. Lying still in a dark, quiet room may help reduce the spinning feeling. Sleep with your head slightly raised on two or more pillows. Get up slowly from a lying or sitting position. Get plenty of rest and try to relax as being anxious can make it worse. Try taking this medicine at bedtime to reduce the symptoms. Drinking plenty of water and ginger tea may also help. Avoid alcohol, caffeine and smoking as it will make you feel worse. Avoid driving or using tools or machinery until you feel better.
  • Coping with Decreased appetite
    It is important to eat, even if you do not feel like it. You might try switching to smaller meals and frequent snacks. Try eating healthy and nutritious snacks that are high in calories and protein, such as dried fruit and nuts. It is important to drink even if you cannot eat. But, do not fill your stomach with liquid before eating. Eat when you are most hungry. Exercise such as a short walk may also increase your appetite. Talk to your doctor about possible medication or supplements if your condition does not improve.
  • Coping with Anxiety
    This often disappears when the condition you are being treated for is managed. You could ask your doctor about changing the dose of your medicine or alternatives if it is affecting your daily life or causing you distress. Psychological treatments may be available. Some things you can do to help yourself include stopping smoking, cutting down the amount of alcohol and caffeine you drink, and doing regular exercise. You should also eat a healthy diet and find out how to get sleep if you are having trouble. Try talking to a friend or family member. Calming breathing exercises and other relaxation techniques may also help.
  • Coping with Constipation
    Try to eat foods which are high in fiber such as fresh fruits, vegetables and cereals to increase the bulk and consistency of bowel movements. Drink plenty of water or non-alcoholic drinks and stay hydrated to promote healthy digestion. Increasing physical activities such as walking, yoga and regular exercise can also be helpful. If your condition does not improve, you can ask your doctor to prescribe you laxative medicine.
  • Coping with Increased sweating
    Try wearing loose, light-weighted, and breathable clothing. Use a strong antiperspirant and keep yourself cool with a fan. Changing your shoes and socks often might also help. Try cutting down on coffee, tea, and alcohol as they can increase your body temperature and promote sweating. Avoid spicy foods, this will help you deal with excessive sweating. If this does not help, talk to your doctor about other possible medications.

How to use Venlift Capsule PR

Use it as advised by your doctor or check the label for directions before use. Venlift OD 37.5 Capsule PR is to be taken with food.

How Venlift Capsule PR works

Venlift OD 37.5 Capsule PR works by increasing the levels of chemical messengers (serotonin and noradrenaline), natural substances in the brain that help maintain mental balance.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Venlift OD 37.5 Capsule PR.
Pregnancy
CONSULT YOUR DOCTOR
Venlift OD 37.5 Capsule PR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Venlift OD 37.5 Capsule PR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Babies should be monitored for excessive sleepiness and adequate weight gain.
Driving
UNSAFE
Venlift OD 37.5 Capsule PR may cause side effects which could affect your ability to drive.
As side effects of Venlift OD 37.5 Capsule PR are dizziness, confusion and eye sight changes such as blurred vision and this may affect your ability to drive.
Kidney
CAUTION
Venlift OD 37.5 Capsule PR should be used with caution in patients with kidney disease. Dose adjustment of Venlift OD 37.5 Capsule PR may be needed. Please consult your doctor.
Liver
CAUTION
Venlift OD 37.5 Capsule PR should be used with caution in patients with liver disease. Dose adjustment of Venlift OD 37.5 Capsule PR may be needed. Please consult your doctor.

What if you forget to take Venlift Capsule PR?

If you miss a dose of Venlift OD 37.5 Capsule PR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Venlift OD 37.5 Capsule PR
₹4.58/Capsule PR
₹4.96/Capsule PR
8% costlier

Quick Tips

  • Venlift OD 37.5 Capsule PR helps in treating depression and anxiety.
  • It may also  be used to treat nerve pain from diabetes and some other forms of chronic pain.
  • It may take 2 to 4 weeks for Venlift OD 37.5 Capsule PR to start working. Keep taking it as prescribed.
  • It may cause dizziness and sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • Avoid consuming alcohol when taking Venlift OD 37.5 Capsule PR as it may cause excessive drowsiness and increase the risk of liver damage.
  • It may cause a sensation of restlessness, especially when you first start taking it. Inform your doctor if this happens to you.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
  • Do not stop taking the medication suddenly without talking to your doctor.

Interaction with Drugs

Taking Venlift with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Lizolan, Lidoford, Mapzolide
LIFE-THREATENING
Brand(s): Trima, Rimarex, Morex
LIFE-THREATENING
Brand(s): Rasalect, Relgin, Rasipar
LIFE-THREATENING
Brand(s): Jumex
LIFE-THREATENING

Patient Concerns

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Mental Depression , Anxiety disorder
Dr. Jyoti Kapoor Madan
Psychiatry
Depression is a persistent state of sadness that is the result of interaction between one's inner biological and psychological state and gets triggered of with environmental stressors. Reactive depression is in response to a situation like loss, sickness, trauma etc. Endogenous depression occurs without any noticeable environmental stressors. Psychological symptoms include lack of interest, negative thinking, irritability, frustration, feeling demotivated etc. Somatic symptoms like fatigue/ weakness/ lack of sleep/ lack of appetite and other physical symptoms are common. Anxiety is common. In severe cases one may feel helpless and hopeless enough to wish for death or attempt suicide. Treatment includes physical and psychiatric work up following which medicines can be prescribed. In milder cases, psychotherapy or counselling is recommended.
Mixed anxiety depressive disorder
Dr. Jyoti Kapoor Madan
Psychiatry
Depression is a persistent state of sadness that is the result of interaction between one's inner biological and psychological state and gets triggered of with environmental stressors. Reactive depression is in response to a situation like loss, sickness, trauma etc. Endogenous depression occurs without any noticeable environmental stressors. Psychological symptoms include lack of interest, negative thinking, irritability, frustration, feeling demotivated etc. Somatic symptoms like fatigue/ weakness/ lack of sleep/ lack of appetite and other physical symptoms are common. Anxiety is common. In severe cases one may feel helpless and hopeless enough to wish for death or attempt suicide. Treatment includes physical and psychiatric work up following which medicines can be prescribed. In milder cases, psychotherapy or counselling is recommended.
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FAQs

Q. Can Venlift cause sedation?

Yes. Venlift can cause sedation. You should inform your doctor if you are taking any other sleep inducing medicines before starting Venlift.

Q. Is Venlift a psychotropic drug?

Yes. Venlift is a psychotropic drug. Any medication capable of affecting the mind, emotions, and behaviour are called psychotropic drugs.

Q. Is Venlift a narcotic?

No. Venlift is not a narcotic drug. Narcotics are drugs with sleep inducing properties, usual derivatives of Opium like Heroin and Morphine.

Q. What is the difference between Venlift ER and XR?

Both are same medication. Venlift ER and XR both means extended release preparation which releases the medication slowly into the body and maintains a constant needed medications levels. The advantage of taking ER/XR tablets is the frequency of dosage can be decreased.

Q. Can I take mirtazapine along with Venlift?

No. There can be a serious side effect when mirtazapine is taken with Venlift. It can cause a serious condition called as serotonin syndrome. It is a potentially life-threatening can present as agitation, hallucinations, nausea, vomiting, diarrhoea, tachycardia, labile blood pressure, hyperthermia and coma.

Q. Can I take Venlift with citalopram?

No. Citalopram and Venlift both increase serotonin levels. Avoid or use any alternate drug. It can cause a serious condition called as serotonin syndrome. It is a potentially life-threatening can present as agitation, hallucinations, nausea, vomiting, diarrhoea, tachycardia, labile blood pressure, hyperthermia and coma.

Q. What is the relation between Venlift and p-glycoprotein?

P-glycoprotein is responsible for the expulsion of Venlift from the brain. Some studies have shown that Venlift and its metabolite inhibit the p-glycoprotein.

Q. Where is Venlift absorbed?

Venlift is absorbed from the intestine after being metabolised by the liver.

Q. When should I take Venlift?

Venlift is a medication to treat generalised depressive disorder or depression. Consult your doctor before taking this medication.

Q. Can Venlift cause high blood pressure?

Venlift treatment is associated with sustained increases in blood pressure in some people. It is recommended that people who are being treated with Venlift should have regular monitoring of blood pressure. For such people, either dose reduction or discontinuation should be considered.

Q. Can Venlift cause constipation?

Yes. Venlift is known to cause constipation in some patients. Take a fiber-rich diet and drink plenty of water. You may consider taking laxatives as well. Your doctor will suggest ways to prevent or manage it. Please consult your doctor if it does not resolve or gets worse.

Q. Can Venlift cause weight loss?

Yes. Venlift is known to cause weight loss in some patients. In research studies, a dose-dependent weight loss was noted in patients treated with Venlift for several weeks. Please consult your doctor if it bothers you.

Q. Can Venlift cause addiction?

No. Venlift does not have habit-forming potential.

Q. Can I take Venlift tablet instead of a capsule?

You can take a tablet instead of the capsule but only under consultation or prescription of a doctor. You should not change it yourself as the different formulation of a medication may have a different action as drug release would be different in both. This can lead to an inappropriate treatment and may lead to side effects or even failure of treatment.

Q. Can gabapentin be given along with Venlift?

Yes. Gabapentin can be given with Venlift but only with a consultation of a doctor. They both, when given together, causes an increase drowsiness, sleepiness and decreased concentration in work. Take with caution.

Q. What is the difference between Venlift and desvenlafaxine?

Desvenlafaxine is an active metabolite of Venlift. It is the same medication in an active form.

Q. Can fibromyalgia be treated with Venlift?

Venlift is not approved for the treatment of fibromyalgia. Some research studies have shown promising results of Venlift in the treatment of fibromyalgia. Consult your doctor before starting this medication.

Q. Can nerve pain be treated with Venlift?

Venlift is not approved for treatment of nerve pain disorders but some researchers have proved its efficacy in nerve pain. It is currently used off-label for nerve pain.

Q. Why does Venlift cause loss of appetite?

Venlift is known to cause changes in the neurotransmitters levels and chemicals in the brain which leads to decrease in appetite and this loss of appetite is dose dependent.

Q. What are good alternatives to Venlift, particularly when a side effect is reduced sex drive?

If you find any side effects like decreased sex drive or impotence talk to your doctor and then you can have some other drug. Do not stop Venlift by yourself it can lead to increased adverse effects.

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References
  1. Stahl SM, editor. Venlafaxine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 721-26.
  2. DeBattista C. Antidepressant Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 513.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1466.
  4. Venlafaxine [FDA Label]. Marietta, GA: Urban Pharmaceuticals Inc.; 1993 [revised Jun. 2014]. [Accessed 19 Mar. 2019] (online) Available from:External Link
  5. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Venlafaxine. [Updated 2019 Oct 23]. [Accessed 20 Feb. 2020] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:External Link
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