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Valmeg 450 Tablet

Valganciclovir (450mg)

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Valmeg 450 Tablet is used to treat cytomegalovirus (CMV) infection of the retina (retinitis) in adult patients with acquired immunodeficiency syndrome (AIDS). It is also used for the prevention of CMV infection in patients who have received an organ transplant from a CMV-infected donor.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 08 May 2026 | 03:58 PM (IST)

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General Information

Contains

Valganciclovir (450mg)

Marketer

Rencord Life Sciences Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Valmeg 450 Tablet should be taken in the dose and duration as advised by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. It should be taken with food. You should drink plenty of water while on treatment with this medicine, as it helps prevent dehydration and kidney damage.

Valmeg 450 Tablet may cause a few common side effects like diarrhea, vomiting, anemia, low white blood cells, low platelet levels, insomnia, and vomiting. Inform your doctor if these side effects persist for a longer duration.

Before you start Valmeg 450 Tablet, let your doctor know if you have any medical conditions. Let your doctor also know about all the medications you are taking, as some medicines may interact with Valmeg 450 Tablet. Please consult your doctor if you are pregnant, planning to conceive, or breastfeeding.

Uses of Valmeg Tablet

Herpes labialis
Treatment of Cytomegalovirus Infection
Genital herpes infection
Chickenpox
Herpes Simplex Virus Infections
Eye infections by Herpes simplex virus
Chronic hepatitis C virus (HCV) infection

Benefits of Valmeg Tablet

Treatment of Cytomegalovirus Infection
Cytomegalovirus infection is a common virus infection which may have no symptoms at all or may have symptoms like fever and fatigue. Severe infection may show symptoms involving the eyes, brain, or other internal organs. This virus is spread through sexual and nonsexual contact with body secretions in people who are immunocompromised or those who have undergone any transplant. Valmeg 450 Tablet helps to prevent multiplication of the infection causing virus and treats the infection. Keep taking it in the dose and duration prescribed by the doctor to get maximum benefit.

Side effects of Valmeg Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Valmeg

Diarrhea
Fever
Fatigue
Nausea
Tremors
Decreased white blood cell count (neutrophils)
Anemia (low number of red blood cells)
Decreased white blood cell count
Low blood platelets
Headache
Insomnia (difficulty in sleeping)
Vomiting
Urinary tract infection

How to use Valmeg Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Valmeg 450 Tablet should be taken with or after food.

How Valmeg Tablet works

Valmeg 450 Tablet is an antiviral medication. It prevents the multiplication of viruses in human cells. This stops the virus from producing new viruses and clears up your infection.

All substitutes for Valmeg 450 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Take Valmeg 450 Tablet exactly as prescribed by your doctor to effectively control CMV retinitis and prevent the worsening of the infection.
Regular blood tests may be required to monitor your blood cell counts, as Valmeg 450 Tablet can cause low white blood cells (leukopenia) and low platelets (thrombocytopenia).
Inform your doctor if you experience unusual bleeding, persistent fever, vision changes, or severe fatigue, as these may indicate serious side effects.
Use effective contraception during treatment and for at least 90 days after stopping the medication, as Valmeg 450 Tablet may cause birth defects.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Valmeg 450 Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Valmeg 450 Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Valmeg 450 Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Valmeg 450 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

Valmeg 450 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

SAFE IF PRESCRIBED

Valmeg 450 Tablet is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Interaction with drugs

Taking Valmeg with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Tacrolimus (Oral Route)

If concurrent use is essential, your doctor may monitor your tacrolimus levels, potassium levels and kidney function closely. They may adjust the doses as per the observations.

Severe

Tenofovir disoproxil fumarate (Oral Route)

Concurrent use may increase the risk of kidney damage.

Moderate

Amphotericin B (Injection Route)

If concurrent use is essential, please consult your doctor. They may monitor your kidney's functioning closely. Amphotericin B may slow down the removal of Valganciclovir from the body.

Moderate

Amphotericin B (Vaginal Route)

If concurrent use is essential, please consult your doctor. They may monitor your kidney's functioning closely. Amphotericin B may slow down the removal of Valganciclovir from the body.

Moderate

Cidofovir (Injection Route)

If concurrent use is essential, please consult your doctor. They may monitor your kidney's functioning closely. Cidofovir may slow down the removal of Valganciclovir from the body.

Frequently asked questions

What is valganciclovir used for?

Valmeg 450 Tablet is used for the treatment of cytomegalovirus (CMV) infection of the retina (retinitis) in adult patients with acquired immunodeficiency syndrome (AIDS). It is also used for the prevention of CMV infection in patients who have received an organ transplant from a CMV-infected donor.

How does valganciclovir work?

After being taken orally, Valmeg 450 Tablet gets converted into ganciclovir by liver and intestinal enzymes, which then prevents the growth and spread of cytomegalovirus.

Does Valmeg 450 Tablet cover herpes simplex virus (HSV)?

Valmeg 450 Tablet can also be used for the treatment of herpes simplex virus (HSV) infection. Please follow the doctor's advice regarding its use.

Fact Box

Chemical Class

Alpha amino acid derivative

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Antiviral Agents (Non-HIV)

Related lab tests

Bilirubin Total

Hepatitis B s (Surface) Antigen

Hepatitis C Virus Total Antibody

Herpes Simplex Virus 1 DNA PCR

Herpes Simplex Virus 1 IgG

Herpes Simplex Virus 2 DNA PCR

Herpes Simplex Virus 2 IgG

Herpes Simplex Virus 2 IgM

Liver Function Test

Varicella Zoster IgG

Varicella Zoster IgM

References

Acosta EP, Flexner C. Antiviral Agents (Nonretroviral). In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1603-605.
Safrin S. Antiviral Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 852.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1446-47.
Alganciclovir [Prescribing Information]. South San Francisco, California: Genentech USA; 2010. [Accessed 01 Apr. 2019] (online) Available from:
Valgaciclovir [Prescribing Information]. Piscataway, NJ: Camber Pharmaceuticals, Inc.; 2025. [Accessed 09 Mar. 2025] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Rencord Life Sciences Pvt Ltd
Address: corporate office : office no. 156, 1st floor, vardhman grand plaza commercial complex, rohini, sec.-3, new delhi-110085

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Valmeg 450 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Valmeg 450 Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Valmeg Tablet

Benefits of Valmeg Tablet

Side effects of Valmeg Tablet

How to use Valmeg Tablet

How Valmeg Tablet works

All substitutes for Valmeg 450 Tablet

Valgan Tablet

Virolfi 450mg Tablet

Cymgal Tablet

Vagacyte 450mg Tablet

Valgacel 450mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Tacrolimus (Oral Route)

Tenofovir disoproxil fumarate (Oral Route)

Amphotericin B (Injection Route)

Amphotericin B (Vaginal Route)

Cidofovir (Injection Route)

Frequently asked questions

What is valganciclovir used for?

How does valganciclovir work?

Does Valmeg 450 Tablet cover herpes simplex virus (HSV)?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Bilirubin Total

Hepatitis B s (Surface) Antigen

Hepatitis C Virus Total Antibody

Herpes Simplex Virus 1 DNA PCR

Herpes Simplex Virus 1 IgG

Herpes Simplex Virus 2 DNA PCR

Herpes Simplex Virus 2 IgG

Herpes Simplex Virus 2 IgM

Liver Function Test

Varicella Zoster IgG

Varicella Zoster IgM

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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