Uroken 1000000IU Injection

Urokinase (1000000IU)

Genuine

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Prescription

required

Cold stored

Stored between 2-8°C

Uroken 1000000IU Injection is a medicine used to break down harmful blood clots that have formed in the blood vessels. It is used to treat patients who have suffered a recent heart attack. It is also used in treating conditions such as pulmonary embolism and stroke.

Written By Dr. Nitika Makhija, MDS, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 18 Aug 2025 | 04:03 PM (IST)

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General Information

Contains

Urokinase (1000000IU)

Marketer

Chandra Bhagat Pharma Pvt Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

The content is shown in English

Product introduction

Uroken 1000000IU Injection is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. The doctor may closely monitor your condition until you become stable.

Use of this medicine may cause nausea, vomiting, injection site bleeding, allergic reaction, and a decrease in blood pressure. It may increase your risk of bleeding also. Your doctor will explain the benefits and risks associated with this medicine before it is administered. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection.

This medicine is used with caution for some people. Thus, you must inform the doctor if you are suffering from any bleeding disorder, kidney, or liver disease. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly.

Uses of Uroken Injection

Benefits of Uroken Injection

Heart attack
Uroken 1000000IU Injection is used in heart attacks to dissolve blood clots that block blood flow to the heart. This helps restore circulation quickly, reduce heart damage, and improve survival outcomes.

Pulmonary embolism
In pulmonary embolism, Uroken 1000000IU Injection helps break down clots in the lungs, improving oxygen flow and relieving symptoms like chest pain and breathlessness. It supports faster recovery and prevents complications.

Side effects of Uroken Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Uroken

Allergic reaction
Nausea
Vomiting
Injection site bleeding
Decreased blood pressure

How to use Uroken Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Uroken Injection works

Uroken 1000000IU Injection works by dissolving the harmful blood clots in the blood vessels. This restores the blood flow to the affected tissue, thereby preventing tissue death and improving outcomes.

Quick tips

It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g. football, wrestling).
Do not discontinue use without consulting your doctor as this may increase your chances of having another heart attack or stroke.
Uroken 1000000IU Injection helps break down blood clots in blood vessels, thereby treating conditions such as heart attack, pulmonary embolism, and stroke.
It should be given as soon as possible (within 12 hours) after the onset of a heart attack.
It is usually given by your nurse or doctor as an infusion (drip) into a vein.
It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g. football, wrestling).
Do not discontinue use without consulting your doctor as this may increase your chances of having another heart attack or stroke.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Uroken 1000000IU Injection. Please consult your doctor.

Pregnancy

SAFE IF PRESCRIBED

Uroken 1000000IU Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

SAFE IF PRESCRIBED

Uroken 1000000IU Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

NOT RELEVANT

Not relevant, as Uroken 1000000IU Injection is intended for use in hospitalised patients.

Kidney

SAFE IF PRESCRIBED

Uroken 1000000IU Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Uroken 1000000IU Injection may not be needed in these patients. Please consult your doctor.
Use of Uroken 1000000IU Injection is not recommended in patients with severe kidney disease.

Liver

CAUTION

Uroken 1000000IU Injection should be used with caution in patients with liver disease. Dose adjustment of Uroken 1000000IU Injection may be needed. Please consult your doctor.

Interaction with drugs

Taking Uroken with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Streptokinase (Injection Route)

Do not consume Streptokinase with Urokinase. If Streptokinase is essential, ensure a gap of At least 5 days between taking Streptokinase and Urokinase. Please consult your doctor. Urokinase may reduce the efficacy of Streptokinase.

Severe

Cilostazol (Oral Route)

Inform your doctor if you notice any signs of bleeding (bruising, bleeding gums, blood in stool/vomit/urine).

Severe

Apixaban (Oral Route)

Do not consume Apixaban with Urokinase. If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Urokinase may increase the effect of Apixaban.

Moderate

Ticagrelor (Oral Route)

Talk to your doctor if you notice any unusual symptoms.

Moderate

Rivaroxaban (Oral Route)

Talk to your doctor if you notice any unusual symptoms.

Frequently asked questions

Can the use of Uroken 1000000IU Injection increase the risk of bleeding?

Yes, Uroken 1000000IU Injection increases the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.

What medicines should I avoid while taking Uroken 1000000IU Injection?

Uroken 1000000IU Injection can interact with several medicines. Do not take any medicine without talking to your doctor.

Fact Box

Chemical Class

Amino acids, Peptides analogues

Habit Forming

Therapeutic Class

CARDIAC

Action Class

First-Generation Thrombolytics

Related lab tests

Platelet Count

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1414-5.
Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Chandra Bhagat Pharma Pvt Ltd
Address: 501, The Bureau, R C MARG, Nr.Chembur Naka, Chembur East, Mumbai - 400071

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Uroken 1000000IU Injection

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Uroken Injection

Benefits of Uroken Injection

Side effects of Uroken Injection

How to use Uroken Injection

How Uroken Injection works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Streptokinase (Injection Route)

Cilostazol (Oral Route)

Apixaban (Oral Route)

Ticagrelor (Oral Route)

Rivaroxaban (Oral Route)

Frequently asked questions

Can the use of Uroken 1000000IU Injection increase the risk of bleeding?

What medicines should I avoid while taking Uroken 1000000IU Injection?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Platelet Count

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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