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Unidep SR 150 Tablet

Written By Dr. Lipika Khurana, PGDHHM, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 23 Jan 2026 | 11:12 AM (IST)
Unidep SR 150 Tablet is used in the treatment of depression and smoking addiction. This medicine helps by increasing the level of chemical messengers in the brain that relax the nerves and have a calming effect on the brain.
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₹93.1 MRP ₹103.1310% off 
 
 
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Unidep SR 150 Tablet is currently sold out
Same composition alternative:
Bupron SR 150 Tablet
₹159₹176.25
Available alternative from Sun Pharmaceuticals
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Unidep SR 150 Tablet
Unidep SR 150 Tablet
strip of 10 tablet er
₹93.1
₹103.13
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Same composition
Bupron SR 150 Tablet
Bupron SR 150 Tablet
strip of 10 tablet er
Bupropion (150mg)
by Sun Pharmaceutical Industries Ltd
Get in 30 mins
₹159
₹13.5 per unit

₹135

order for
₹1200

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General Information

Contains

Bupropion (150mg)

Marketer

Consern Pharma Limited

Storage

Store below 30°C
The content is shown in English
Unidep SR 150 Tablet image
Unidep SR 150 Tablet image

Product introduction

Unidep SR 150 Tablet may be taken with or without food. It is advised to take this medicine at a fixed time each day. You should never skip any doses and finish the full course of treatment even if you feel better. This medication mustn't be stopped suddenly as it may worsen your symptoms.

Some common side effects of this medicine include insomnia (difficulty sleeping), allergic reaction, impaired concentration, sweating, headache, nausea, vomiting, and dry mouth. It even causes dizziness and sleepiness, so do not drive or do anything that requires mental focus. Moreover, most of the side effects are immediate and often go away with time. Please consult your doctor if these bother you or do not go away.

Before taking this medicine it is important to inform your doctor if you have any history of seizure or if you drink alcohol. Inform your doctor if you develop any unusual mood changes or if you have any suicidal thoughts.

Uses of Unidep Tablet ER

Benefits of Unidep Tablet ER

Depression
Depression affects mood, energy levels, and daily activities. Unidep SR 150 Tablet is used to help improve mood and emotional balance in individuals with depression, supporting better focus, motivation, and overall mental well-being.
Smoking addiction
Smoking addiction is driven by nicotine dependence and can be hard to overcome. Unidep SR 150 Tablet is used to aid in quitting smoking by reducing cravings and withdrawal symptoms, making it easier to stop and maintain a smoke-free life.

Side effects of Unidep Tablet ER

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Unidep
  • Insomnia (difficulty in sleeping)
  • Allergic reaction
  • Impaired concentration
  • Sweating
  • Headache
  • Nausea
  • Vomiting
  • Dizziness
  • Dryness in mouth
  • Taste change
  • Abdominal pain
  • Agitation
  • Anxiety
  • Fever
  • Constipation
  • Tremors

How to use Unidep Tablet ER

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Unidep SR 150 Tablet may be taken with or without food.

How Unidep Tablet ER works

Unidep SR 150 Tablet works in depression by increasing the levels of chemical messengers in the brain that helps in regulating mood. The mechanism underlying its use in smoking addiction are not fully understood.

All substitutes for Unidep SR 150 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Bupron SR 150 Tablet

by Sun Pharmaceutical Industries Ltd
₹15.9/tablet er
71% costlier
<h3 class=bodySemiBold>Bupron SR 150 Tablet</h3>

Zupion -SR Tablet

by Intas Pharmaceuticals Ltd
₹15.9/tablet er
71% costlier
<h3 class=bodySemiBold>Zupion -SR Tablet</h3>

Bupro-SR 150 (D.D) Tablet

by D D Pharmaceuticals
₹10.4/tablet er
12% costlier
<h3 class=bodySemiBold>Bupro-SR 150 (D.D) Tablet</h3>

Brunojoy 150 Tablet ER

by Mitis Biomedics Ltd
₹18.3/tablet er
97% costlier
<h3 class=bodySemiBold>Brunojoy 150 Tablet ER</h3>

Quick tips

  • You have been prescribed Unidep SR 150 Tablet for the treatment of depression.
  • It can also help you quit smoking.
  • Take it in the morning to avoid difficulty sleeping later that night.
  • It causes fewer side effects as compared to other anti-depression medications.
  • Stop taking Unidep SR 150 Tablet and inform your doctor if you notice sudden mood and behavior changes or develop suicidal thoughts.
  • Inform your doctor if you have a history of seizure disorder, eating disorder, or if you drink alcohol.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Unidep SR 150 Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Unidep SR 150 Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Unidep SR 150 Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Unidep SR 150 Tablet may cause side effects that could affect your ability to drive.
Unidep SR 150 Tablet may cause dizziness or light-headedness, may affect your concentration and judgement. This may affect your driving ability.
Kidney

Kidney

CAUTION
Unidep SR 150 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Unidep SR 150 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Caution is advised for the use of Unidep SR 150 Tablet in these patients with close monitoring from a doctor for any possible side effects.

Interaction with drugs

Taking Unidep with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Moclobemide (Oral Route)

Do not consume Moclobemide with Bupropion. If Moclobemide is essential, ensure a gap of at least 24 hours after discontinuing Bupropion. Please consult your doctor.
Life-threatening

Safinamide (Oral Route)

Do not consume Safinamide with Bupropion. If Safinamide is essential, ensure a gap of at least 24 hours after discontinuing Bupropion. Please consult your doctor.
Life-threatening

Selegiline (Oral Route)

Do not consume Selegiline with Bupropion. If Selegiline is essential, ensure a gap of at least 2 weeks after discontinuing Bupropion. Please consult your doctor.
Life-threatening

Rasagiline (Oral Route)

Do not consume Rasagiline with Bupropion. If Rasagiline is essential, ensure a gap of at least 2 weeks after discontinuing Bupropion. Please consult your doctor.
Life-threatening

Tranylcypromine (Oral Route)

Do not consume Tranylcypromine with Bupropion. If Tranylcypromine is essential, ensure a gap of at least 2 weeks after discontinuing Bupropion. Please consult your doctor.

Frequently asked questions

No, Unidep SR 150 Tablet should not be used for anxiety or sleeplessness. Instead, it may worsen anxiety. In fact, two of the common side effects are anxiety and sleeplessness. It is because of this that your doctor may even advise you not to take Unidep SR 150 Tablet too close to bedtime.
If Unidep SR 150 Tablet is taken in the correct dose, for the correct duration, and in the correct way as advised by the doctor, then there is no risk of addiction. However, if more than the recommended dose is taken or if the tablets are crushed and inhaled, then abuse potential and addiction are likely.
The risk of seizure appears to be strongly associated with the dose of Unidep SR 150 Tablet. Increasing your dose of Unidep SR 150 Tablet may increase the risk. The risk of seizure increases with regular intake of alcohol, diabetes, serious head injury or history of head trauma, previous seizures, central nervous system tumor or infection, or addiction to cocaine, opiates, or stimulants. The risk also increases with simultaneous use of medicines to treat psychosis or depression, theophylline and oral corticosteroids, or if you are taking medicines that cause loss of appetite (anorectics).
No, it is very rare to develop eye problems such as redness in and around the eyes, eye pain, and blurred vision. Consult your doctor if you notice any such side effects or want to know if you are at risk or not. You can even receive preventative treatment if you are at risk.
Since the risk of seizures is dose-related, you should not exceed the recommended dose. In case you need an increase in the dosage, your doctor will gradually increase the dose. Seizures are more common with Unidep SR 150 Tablet medicines which are released immediately on taking than with prolonged-release preparations. Consult your doctor if you are trying to stop alcohol while using Unidep SR 150 Tablet. It is advised that you reduce your alcohol intake slowly over time.
You may take Unidep SR 150 Tablet while taking captopril, but you need to get your blood pressure regularly checked. Unidep SR 150 Tablet can increase your blood pressure even if you are taking captopril. If your blood pressure increases, then consult your doctor immediately since you may have to stop Unidep SR 150 Tablet.
Excess of Unidep SR 150 Tablet may cause fast heartbeat, drowsiness, changes in electrical activity of the heart (arrhythmias, QT prolongation), and loss of consciousness. The patient should be given immediate medical support.

Fact Box

Chemical Class

Alkyl- phenylketones

Habit Forming

No

Therapeutic Class

NEURO CNS

Action Class

Norepinephrine-Dopamine Reuptake Inhibitors (NDRIs)

References

  1. Stahl SM, editor. Bupropion. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 91-96.
  2. O’Donnell JM, Shelton RC. Drug Therapy of Depression and Anxiety Disorders. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 407.
  3. Bupropion hydrochloride. Uxbridge, Middlesex: GlaxoSmithKline UK; 2004 [21 Mar 2018]. [Accessed 28 Jan. 2019] (online) Available from:
  4. Bupropion hydrochloride. Irvine: Anchen Pharmaceuticals; 2006. [Accessed 20 Mar. 2019] (online) Available from:
  5. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 20 Mar. 2019] (online) Available from:
  7. Bupropion Hydrochloride Extended-Release Tablets. Irvine, California: Anchen Pharmaceuticals, Inc.; 2006. [Accessed 17 Jun. 2019] (online) Available from:
  8. Bupropion hydrochloride. Burgos, Spain: Glaxo Wellcome S.A.; 2017. [Accessed 17 Jun. 2019] (online) Available from:
  9. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006. Bupropion. [Updated 2023 Jan 15]. [Accessed 09 Jun, 2023] (online) Available from:
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User feedback

Once A Day
81%
Twice A Day
19%
Depression
54%
Smoking addiction
46%
Poor
44%
Average
30%
Excellent
26%
Headache
22%
No Side Effect
22%
Insomnia (difficulty in sleeping)
22%
Impaired concentration
22%
Sweating
11%
With food
60%
With or without food
40%
Not Expensive
39%
Average
33%
Expensive
28%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Consern Pharma Limited
Address: 70-71, Ramnik Estate, Village Gonspur, P.O. Nurpur - 141008; H.O.: 308-C, BRS Nagar, Ludhiana, Punjab - 141012, India

Vendor Details

Country of origin: India

Lab tests offered by us

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Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945
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