Ubilon 2.5mg Tablet

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 12 Feb 2026 | 06:11 PM (IST)

Ubilon 2.5mg Tablet is a female sex hormone (estrogen). This is a type of hormone replacement therapy (HRT) that is used to treat symptoms associated with menopause (hot flushes, vaginal dryness, and itching), estrogen deficiency, and thinning of bones (osteoporosis).

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General Information

Contains

Tibolone (2.5mg)

Marketer

Incepta Pharma

Storage

Store below 30°C

The content is shown in English

Product introduction

Ubilon 2.5mg Tablet can be taken with or without food, but better to take it at a fixed time each day for better efficacy. It should be swallowed whole with water. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. If you have missed a dose, take it as soon as you remember it. Do not skip any dose and finish the full course of treatment. The treatment should not be stopped abruptly without consulting your doctor as this may affect the potency of this medicine.

The most common side effects of this medicine are lower abdominal pain, abnormal hair growth, vaginal discharge, breast tenderness, genital itching, vaginal bleeding, pelvic pain, cervical thickening, and weight gain. Some of the warning signs and symptoms that need immediate medical attention are breast lumps, unusual vaginal bleeding, dizziness and faintness, severe headaches, chest pain, shortness of breath, pains in your legs. If you experience any such effects, consult your doctor.

Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. Before you initiate with this HRT, you must consult the doctor if you have a history of unexplained vaginal bleeding or if you have ever had a blood clot in your legs or your lungs. If you are pregnant or breastfeeding, you should tell your doctor before taking this medicine. Your doctor may suggest you some diagnostic or laboratory tests to know the effects and side effects of this medicine on your body.

Uses of Ubilon Tablet

Benefits of Ubilon Tablet

Post menopausal osteoporosis
Osteoporosis is a common condition that weakens bones, making them fragile and more likely to break. It often occurs in women after menopause. Ubilon 2.5mg Tablet helps maintain bone density and reduces your risk of breaking a bone. You should use this medicine as it is prescribed, and for as long as it is prescribed by your doctor.
You can help improve the strength of your bones by doing regular exercise (especially weight-bearing exercise), eating healthy foods containing calcium and Vitamin D and reducing your consumption of alcohol and tobacco. Supplements of calcium and Vitamin D3 are also effective.

Hormone replacement therapy
Hormone replacement therapy (HRT) is a treatment to relieve symptoms of menopause such as hot flushes, night sweats, mood swings, vaginal dryness, and reduced sex drive. Since menopause can last for several years, this treatment can make a big improvement to your daily life and mood. Estrogen is one of two important hormones (the other is progesterone) used in this treatment. You should use this medicine as it is prescribed, and for as long as it is prescribed by your doctor.

Side effects of Ubilon Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ubilon

Weight gain
Vaginal bleeding
Vaginal discharge
Breast tenderness
Genital itching
Abnormal hair growth

How to use Ubilon Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ubilon 2.5mg Tablet may be taken with or without food.

How Ubilon Tablet works

Ubilon 2.5mg Tablet is a hormonal medication. It has effects similar to estrogen, progesterone and androgen. It substitutes for the loss of estrogen production in postmenopausal women and treats menopausal symptoms such as hot flashes, night sweats and vaginal problems. It also prevents bone loss following menopause.

All substitutes for Ubilon 2.5mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Sibolone Tablet

by Serum Institute Of India Ltd

₹25.93/tablet

51% cheaper

Quick tips

Ubilon 2.5mg Tablet is used as a part of hormone replacement therapy to relieve symptoms of menopause such as hot flushes, vaginal dryness, depression, and night sweats.
It may also be used for preventing osteoporosis in women who have attained menopause and are at high risk of fractures.
Take it at the same time everyday to help you remember to take it.
It may cause bleeding or spotting in between menstrual periods. Let your doctor know if this occurs frequently.
Stop taking Ubilon 2.5mg Tablet and inform your doctor immediately if you get severe headaches, stabbing pains or swelling in one leg, and pain on breathing. These could be symptoms of a blood clot in a vein.
Ensure that you regularly check your breasts for any changes and undergo regular breast screening and cervical smear tests while on treatment with this medicine.
Do not use Ubilon 2.5mg Tablet if you have a history of blood clots and liver disease.
Ubilon 2.5mg Tablet is used as a part of hormone replacement therapy to relieve symptoms of menopause such as hot flushes, vaginal dryness, depression, and night sweats.
It may also be used for preventing osteoporosis in women who have attained menopause and are at high risk of fractures.
Take it at the same time everyday to help you remember to take it.
It may cause bleeding or spotting in between menstrual periods. Let your doctor know if this occurs frequently.
Stop taking Ubilon 2.5mg Tablet and inform your doctor immediately if you get severe headaches, stabbing pains or swelling in one leg, and pain on breathing. These could be symptoms of a blood clot in a vein.
Ensure that you regularly check your breasts for any changes and undergo regular breast screening and cervical smear tests while on treatment with this medicine.
Do not use Ubilon 2.5mg Tablet if you have a history of blood clots and liver disease.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Ubilon 2.5mg Tablet. Please consult your doctor.

Pregnancy

UNSAFE

Ubilon 2.5mg Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

UNSAFE

Ubilon 2.5mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Ubilon 2.5mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

Ubilon 2.5mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Ubilon 2.5mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Ubilon with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Fulvestrant (Injection Route)

Do not consume Fulvestrant with Tibolone if you have or had breast cancer. If essential, consult your doctor. Tibolone may reduce the efficacy of Fulvestrant.

Severe

Raloxifene (Oral Route)

Do not consume Raloxifene with Tibolone. If concurrent use is essential, please consult your doctor. Tibolone may reduce the efficacy of Raloxifene.

Severe

Darunavir (Oral Route)

It is recommended to use barrier methods (like condoms), IUDs, or a depot for contraception. Your doctor may monitor your treatment closely and adjust the doses as per the observations. Use barrier methods (like condoms) for contraception to reduce the risk of HIV infection.

Severe

Mycophenolate mofetil (Oral Route)

Effective contraception must be used before, during, and for at least 6 weeks after stopping Mycophenolate mofetil. It is recommended to consult your doctor. Mycophenolate mofetil may reduce the efficacy of Tibolone.

Severe

Perampanel (Oral Route)

Frequently asked questions

Does Ubilon 2.5mg Tablet contain progesterone?

It is a synthetic medicine which is used to fulfill the functions of the normal sex hormones like estrogen and progesterone in the body of women. On taking Ubilon 2.5mg Tablet it is broken down in our body and functions like estrogen, progesterone and a part to testosterone (male sex hormone). It is prescribed to compensate for the loss of estrogen production in postmenopausal women and decrease the menopausal symptoms.

Is Ubilon 2.5mg Tablet a combined HRT?

Yes, Ubilon 2.5mg Tablet is a type of medicine used in hormone replacement therapy (HRT) which is given to post-menopausal women. It is given to prevent the adverse effects on various organs and systems due to decrease in the levels of hormones like estrogen and progesterone. It shows positive effect on different tissues in the body, such as brain, vagina, and bones.

Can Ubilon 2.5mg Tablet be taken during pregnancy?

No, Ubilon 2.5mg Tablet is not to be taken in pregnancy or if you are planning to get pregnant. In case you become pregnant during treatment with this medication you should contact your doctor and the medicine should be withdrawn immediately.

Does Ubilon 2.5mg Tablet help in elevating mood?

Yes, this medicine has shown positive results when given to postmenapausal women as a substitute for the hormonal deprivation. Patients have experienced reduction in the menopausal complaints like persistent fatigue, blunted motivation, and loss of sexual desire. However, consult the doctor regarding any query for your mood problems before you start taking this medication.

Can Ubilon 2.5mg Tablet help in osteoporosis?

Yes, Ubilon 2.5mg Tablet can help in osteoporosis. After menopause some women become prone to develop fragile bones called osteoporosis which can lead to an increased risk of fractures. Ubilon 2.5mg Tablet acts as a replacement for the female sex hormones when given in the post-menopausal phase. These hormones help in increasing bone density. Therefore, taking Ubilon 2.5mg Tablet can prevent bone loss and osteoporosis. Do consult your doctor before starting this medication as you might need other supplemental medications to treat osteoporosis.

Fact Box

Chemical Class

Oxosteroids

Habit Forming

Therapeutic Class

GYNAECOLOGICAL

Action Class

Estrogens

Related lab tests

Calcium

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Incepta Pharma
Address: Parshvnath Tower, Subhash Chowk, Mem Nagar, Ahmedabad-302002 (Gujarat)

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Ubilon 2.5mg Tablet

Save more with additional offers

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Ubilon Tablet

Benefits of Ubilon Tablet

Side effects of Ubilon Tablet

How to use Ubilon Tablet

How Ubilon Tablet works

All substitutes for Ubilon 2.5mg Tablet

Sibolone Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Fulvestrant (Injection Route)

Raloxifene (Oral Route)

Darunavir (Oral Route)

Mycophenolate mofetil (Oral Route)

Perampanel (Oral Route)

Frequently asked questions

Does Ubilon 2.5mg Tablet contain progesterone?

Is Ubilon 2.5mg Tablet a combined HRT?

Can Ubilon 2.5mg Tablet be taken during pregnancy?

Does Ubilon 2.5mg Tablet help in elevating mood?

Can Ubilon 2.5mg Tablet help in osteoporosis?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Calcium

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests