Information about Tibolone

Tibolone Uses

How Tibolone works

Tibolone is a hormonal medication. It has effects similar to estrogen, progesterone and androgen. It substitutes for the loss of estrogen production in postmenopausal women and treats menopausal symptoms such as hot flashes, night sweats and vaginal problems. It also prevents bone loss following menopause.

Common side effects of Tibolone

Abnormal hair growth, Vaginal bleeding, Weight gain, Breast tenderness, Endometrial hyperplasia, Lower abdominal pain, Vaginal discharge, Genital itching, Pelvic pain, Abnormal cervical smear, Vaginal yeast infection, Postmenopausal hemorrhage, Cervical dysplasia
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Reviewed By
MD (Pharmacology), MBBS
Last updated
18 Feb 2020 | 11:51 AM (UTC)

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Available Medicine for Tibolone

TibofemCipla Ltd
4431 variant(s)
LivialOrganon (India) Ltd
17541 variant(s)
SiboloneSerum Institute Of India Ltd
3851 variant(s)
TibomaxZydus Cadila
2091 variant(s)
MaxtibSun Pharmaceutical Industries Ltd
3091 variant(s)
TiboloneCipla Ltd
4071 variant(s)

Expert advice for Tibolone

  • Tibolone is used as a part of hormone replacement therapy to relieve symptoms of menopause such as hot flushes, vaginal dryness, depression, and night sweats.
  • It may also be used for preventing osteoporosis in women who have attained menopause and are at high risk of fractures.
  • Take it at the same time everyday to help you remember to take it.
  • It may cause bleeding or spotting in between menstrual periods. Let your doctor know if this occurs frequently.
  • Stop taking Tibolone and inform your doctor immediately if you get severe headaches, stabbing pains or swelling in one leg, and pain on breathing. These could be symptoms of a blood clot in a vein.
  • Ensure that you regularly check your breasts for any changes and undergo regular breast screening and cervical smear tests while on treatment with this medicine.
  • Do not use Tibolone if you have a history of blood clots and liver disease. 

Frequently asked questions for Tibolone


Q. Does Tibolone contain progesterone?

It is a synthetic medicine which is used to fulfill the functions of the normal sex hormones like estrogen and progesterone in the body of women. On taking Tibolone it is broken down in our body and functions like estrogen, progesterone and a part to testosterone (male sex hormone). It is prescribed to compensate for the loss of estrogen production in postmenopausal women and decrease the menopausal symptoms.

Q. Is Tibolone a combined HRT?

Yes, Tibolone is a type of medicine used in hormone replacement therapy (HRT) which is given to post-menopausal women. It is given to prevent the adverse effects on various organs and systems due to decrease in the levels of hormones like estrogen and progesterone. It shows positive effect on different tissues in the body, such as brain, vagina, and bones.

Q. Can Tibolone be taken during pregnancy?

No, Tibolone is not to be taken in pregnancy or if you are planning to get pregnant. In case you become pregnant during treatment with this medication you should contact your doctor and the medicine should be withdrawn immediately.

Q. Does Tibolone help in elevating mood?

Yes, this medicine has shown positive results when given to postmenapausal women as a substitute for the hormonal deprivation. Patients have experienced reduction in the menopausal complaints like persistent fatigue, blunted motivation, and loss of sexual desire. However, consult the doctor regarding any query for your mood problems before you start taking this medication.

Q. Can Tibolone help in osteoporosis?

Yes, Tibolone can help in osteoporosis. After menopause some women become prone to develop fragile bones called osteoporosis which can lead to an increased risk of fractures. Tibolone acts as a replacement for the female sex hormones when given in the post-menopausal phase. These hormones help in increasing bone density. Therefore, taking Tibolone can prevent bone loss and osteoporosis. Do consult your doctor before starting this medication as you might need other supplemental medications to treat osteoporosis.


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