Tyridol 100mg Suppository

Tramadol (100mg)

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Tyridol 100mg Suppository is a pain-relieving medicine. It is used for the treatment of moderate to severe pain. This route is generally given to those who cannot receive other modes of administration.

Written By Dr. Mayank, Pharm.D,
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology,
Last updated on 21 Sep 2025 | 06:01 PM (IST)

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General Information

Contains

Tramadol (100mg)

Marketer

Bliss Gvs Pharma Limited

Storage

Store below 30°C

The content is shown in English

Product introduction

Tyridol 100mg Suppository is taken by the back passage (rectal route) and should not be taken orally. It must be given under the supervision of a doctor only. You should stay in a lying position for at least 15 minutes after insertion of suppositories. The dose will depend on what you are being treated for but take it exactly as your doctor prescribes.

The most common side effects of this medicine include nausea, dizziness, vomiting, constipation, and sleepiness. If these symptoms bother you, do not go away, or get worse, you should tell your doctor. Your doctor may be able to suggest ways of preventing or reducing the symptoms.

Before taking it, tell your doctor if you have any kidney or liver problems or a blockage in your stomach. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.

Uses of Tyridol Suppository

Moderate to severe pain

Benefits of Tyridol Suppository

Moderate to severe pain
Tyridol 100mg Suppository helps to relieve moderate to severe pain in people who are unable to take the painkiller by mouth (orally). It works by blocking chemical messengers in the brain that tell us we have pain. It is given under the supervision of a doctor only through the rectal area. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Tyridol Suppository

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Tyridol

Dizziness
Sleepiness
Vomiting
Nausea
Constipation

How to use Tyridol Suppository

Remove the wrapper from the suppository before inserting it. Keep lying down for about 15 minutes after insertion so that the suppository does not come out before it melts.

How Tyridol Suppository works

Tyridol 100mg Suppository is an opioid analgesic (pain reliever) that is absorbed rapidly into the bloodstream from the rich blood supply of the rectal area. Once absorbed, it works by blocking the transmission of pain signals to the brain to lower pain perception.

Quick tips

Lie down on your side while inserting Tyridol 100mg Suppository to make it easier and more comfortable.
Lie down for a few minutes after using it so the medicine does not slip out.
Avoid alcohol or other sleep-inducing medicines, as they can increase drowsiness or slow down your breathing.
If you feel dizzy, confused, or very sleepy, tell your doctor as it might be a sign that the Tyridol 100mg Suppository dose is too strong.
Do not use Tyridol 100mg Suppository more often than told by your doctor, as it can lead to serious side effects or dependence.

Safety advice

Alcohol

No interaction found/established

Pregnancy

CONSULT YOUR DOCTOR

Tyridol 100mg Suppository may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Tyridol 100mg Suppository is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Consult a doctor immediately if the baby shows signs of increased sleepiness (more than usual), difficulty breastfeeding, breathing problems, or limpness.

Driving

No interaction found/established

Kidney

CAUTION

Tyridol 100mg Suppository should be used with caution in patients with kidney disease. Dose adjustment of Tyridol 100mg Suppository may be needed. Please consult your doctor.

Liver

CAUTION

Tyridol 100mg Suppository should be used with caution in patients with liver disease. Dose adjustment of Tyridol 100mg Suppository may be needed. Please consult your doctor.

Interaction with drugs

Taking Tyridol with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Moclobemide (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.

Severe

Amitriptyline (Oral Route)

Careful consideration is advised if you have epilepsy. Watch out for symptoms of serotonin syndrome, such as sedation, respiratory impairment, tremors, fever, diarrhea, or agitation, and consult your doctor if you experience them. Your doctor may alter or discontinue the medicines accordingly.

Severe

Clomipramine (Oral Route)

Severe

Dosulepin (Oral Route)

Severe

Doxepin (Oral Route)

Frequently asked questions

Is there anything I need to be careful about while on therapy with Tyridol 100mg Suppository?

Tyridol 100mg Suppository may cause drowsiness and dizziness, especially in the beginning of the treatment. Do not drive or work with tools or machinery if your alertness is affected. It is not advisable to drink alcohol during treatment with this medicine as it might increase sleepiness.

Fact Box

Chemical Class

Anisole Derivative

Habit Forming

Yes

Therapeutic Class

PAIN ANALGESICS

Action Class

Opioids

References

Schumacher MA, Basbaum AI, Way WL. Opioids Analgesics & Antagonists. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 547.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1384-86.
ScienceDirect. Tramadol. [Accessed 02 Apr. 2019] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Bliss Gvs Pharma Limited
Address: Bliss GVS Pharma Ltd., 102,Hyde Park, Saki Vihar Road, Andheri (East),Mumbai – 400072, India

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Tyridol 100mg Suppository

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Tyridol Suppository

Benefits of Tyridol Suppository

Side effects of Tyridol Suppository

How to use Tyridol Suppository

How Tyridol Suppository works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Moclobemide (Oral Route)

Amitriptyline (Oral Route)

Clomipramine (Oral Route)

Dosulepin (Oral Route)

Doxepin (Oral Route)

Frequently asked questions

Is there anything I need to be careful about while on therapy with Tyridol 100mg Suppository?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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