Trinel Capsule

Nelfinavir (250mg)

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Trinel Capsule is an antiviral or antiretroviral medicine. It is used in the treatment of HIV infection. It stops the virus from producing new viruses and clears up your infection.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 22 Sep 2025 | 01:41 PM (IST)

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Gurgaon

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General Information

Contains

Nelfinavir (250mg)

Marketer

Triveni Formulations Limited

The content is shown in English

Product introduction

Trinel Capsule should be taken with food, as this increases the absorption of the medicine into the body. You should take it in the dose and duration as advised by your doctor. Taking it at the same time every day will help you to remember to take it. Do not stop taking it until you have finished the complete course, even when you feel better. If you stop taking this medicine too early then infection may return or worsen.

Some people may experience headaches, dizziness, nausea, vomiting, and diarrhea as side effects of this medicine. Please consult your doctor if these side effects persist for a longer duration. Inform your doctor if you have diabetes as it can increase sugar levels in the blood.

Before using it, you should tell your doctor if you are allergic to any antibiotics or have any kidney or liver problems. You should also let your doctor know all other medicines you are taking as they may affect, or be affected by this medicine. Pregnant and breastfeeding mothers should consult their doctor before using it. Your doctor may monitor your liver function while taking this medication.

Uses of Trinel Capsule

HIV infection

Benefits of Trinel Capsule

HIV infection
Trinel Capsule is used as part of combination therapy to manage HIV infection. It helps lower the amount of virus in the body, supports immune system function, and reduces the risk of HIV-related illnesses and complications.

Side effects of Trinel Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Trinel

Rash
Nausea
Diarrhea
Flatulence
Abdominal pain
Decreased appetite

How to use Trinel Capsule

Take this medicine in the dose and duration as advised by your doctor. Trinel Capsule is to be taken with food.

How Trinel Capsule works

Trinel Capsule is an anti-HIV medication. It works by interfering with an enzyme (protease), which is required by HIV-infected cells to make new viruses. This stops the production of new viruses.

Quick tips

Trinel Capsule should be taken with food.
Do not skip any doses and finish the full course of treatment even if you feel better.
It may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
Your doctor may check your liver function regularly. Inform your doctor if you develop abdominal pain, loss of appetite darkened urine or yellowing of the eyes or skin (jaundice).
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Trinel Capsule should be taken with food.
Do not skip any doses and finish the full course of treatment even if you feel better.
Do not take antacids an hour before or two hours after taking Trinel Capsule.
It may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with this medicine.
Your doctor may check your liver function regularly. Inform your doctor if you develop abdominal pain, loss of appetite darkened urine or yellowing of the eyes or skin (jaundice).
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Trinel Capsule. Please consult your doctor.

Pregnancy

SAFE IF PRESCRIBED

Trinel Capsule is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

SAFE IF PRESCRIBED

Trinel Capsule is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Trinel Capsule alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

SAFE IF PRESCRIBED

Trinel Capsule is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Trinel Capsule may not be needed in these patients. Please consult your doctor.

Liver

CAUTION

Trinel Capsule should be used with caution in patients with liver disease. Dose adjustment of Trinel Capsule may be needed. Please consult your doctor.
Use of Trinel Capsule is not recommended in patients with moderate and severe liver disease.

Interaction with drugs

Taking Trinel with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Docetaxel (Injection Route)

Nelfinavir may raise blood levels of Docetaxel. Nelfinavir may raise blood levels of Docetaxel.

Severe

Trabectedin (Injection Route)

Nelfinavir may raise blood levels of Trabectedin. Nelfinavir may raise blood levels of Trabectedin.

Severe

Ceritinib (Oral Route)

Nelfinavir may raise blood levels of Ceritinib. Nelfinavir may raise blood levels of Ceritinib.

Moderate

Bevacizumab (Injection Route)

Your doctor may monitor effects and adjust the treatment plan involving Bevacizumab.

Moderate

Cabazitaxel (Injection Route)

If concurrent use is essential, your doctor may closely monitor treatment outcomes and may modify treatment if required.

Frequently asked questions

What is Trinel Capsule used for?

Trinel Capsule is a protease inhibitor used for the treatment for human immunodeficiency virus (HIV) infection, along with other medications (other antiretroviral agents).

Fact Box

Chemical Class

Alpha amino acid amides

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Protease Inhibitors

Related lab tests

HIV 1 & 2, Ab Western Blot

HIV 1 And 2 Antibody - Chromatography

HIV 1 And 2 Antibody - ELISA

References

Flexner C. Antiretroviral Agents and Treatment of HIV Infection. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1654-655.
Safrin S. Antiviral Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 864.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 966-68.
ScienceDirect. Nelfinavir. [Accessed 01 Apr. 2019] (online) Available from:
Nelfinavir. Research Triangle Park, North Carolina: ViiV Healthcare Company; 1997 [revised Apr. 2013]. [Accessed 01 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 01 Apr. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Triveni Formulations Limited
Address: ALEAP Industrial Area, industrial estates, Surampalli, Andhra Pradesh 521212

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Trinel Capsule

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General Information

Contains

Marketer

Product introduction

Uses of Trinel Capsule

Benefits of Trinel Capsule

Side effects of Trinel Capsule

How to use Trinel Capsule

How Trinel Capsule works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Docetaxel (Injection Route)

Trabectedin (Injection Route)

Ceritinib (Oral Route)

Bevacizumab (Injection Route)

Cabazitaxel (Injection Route)

Frequently asked questions

What is Trinel Capsule used for?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

HIV 1 & 2, Ab Western Blot

HIV 1 And 2 Antibody - Chromatography

HIV 1 And 2 Antibody - ELISA

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests