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Nelfinavir is used in the treatment of hiv infection

How it works

Nelfinavir prevents the multiplication of HIV virus in human cells. Thus stops the HIV virus from producing new viruses.

Common side effects

Rash, Headache, Dizziness, Muscle pain, Insomnia (difficulty in sleeping), Vomiting, Weakness, Nausea, Abdominal pain, Loss of appetite, Dyspepsia, Circumoral paresthesia, Paresthesia (tingling or pricking sensation), Glucose intolerance, Jaundice, Fatigue, Fever, Incresed blood lipid level, Diarrhoea, Peripheral neuropathy (tingling and numbness of feet and hand), Depression, Feeling of discomfort, Altered taste, Increased cholesterol level in blood, Increased triglyceride level in blood, Increased glucose level in blood

Available Medicine

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Expert advice

  • Your blood glucose levels should be monitored regularly as development and worsening of diabetes have been reported during nelfinavir treatment.
  • Tell your doctor if you have liver or kidney functioning problems, bleeding disorder (hemophilia),  phenylketonuria (a serious hereditary disorder) or high blood cholesterol or triglycerides.
  • You should be monitored regularly for signs of any infection or inflammatory reactions indicating changes in immune system.
  • Nelfinavir is not recommended for use in children aged below 3 years.
  • Treatment with nelfinavir along with other anti-HIV medications can cause lipodystrophy (changes in body fat - build up or loss of body fat) usually resulting in increase of fat in breasts, neck, chest, stomach, upper back and loss of fat from legs, arms, and face.
  • You must take necessary precautions (practicing safer sex and making other life-style changes) to avoid spreading of HIV virus to others.
  • Tell your doctor if you are pregnant or planning to become pregnant.

Frequently asked questions



What is nelfinavir used for?
Nelfinavir is a protease inhibitor used for the treatment for human immunodeficiency virus (HIV) infection, along with other medications (other antiretroviral agents).

Content on this page was last updated on 27 March, 2017, by Dr. Varun Gupta (MD Pharmacology)