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Nelfinavir

INFORMATION

Uses

Nelfinavir is used in the treatment of HIV infection.

How it works

Nelfinavir is an antiretroviral medication belonging to the class, protease inhibitors. It works by inhibiting the action of a viral enzyme called protease, which is essential for maturation of the HIV virus resulting in the production of immature, non-infectious virus and reducing the number of HIV causing virus in the body.

Common side effects

Vomiting, Nausea, Kidney stone, Abdominal pain, Acne-like rash, Anxiety, Back pain, Bloody diarrhea, Cardiac disorder, Flatulence, Increased creatine level in blood, Increased blood urea, Loss of appetite, Muscle pain

AVAILABLE MEDICINE

Expert advice

  • Your blood glucose levels should be monitored regularly as development and worsening of diabetes have been reported during nelfinavir treatment.
  • Tell your doctor if you have liver or kidney functioning problems, bleeding disorder (hemophilia),  phenylketonuria (a serious hereditary disorder) or high blood cholesterol or triglycerides.
  • You should be monitored regularly for signs of any infection or inflammatory reactions indicating changes in immune system.
  • Nelfinavir is not recommended for use in children aged below 3 years.
  • Treatment with nelfinavir along with other anti-HIV medications can cause lipodystrophy (changes in body fat - build up or loss of body fat) usually resulting in increase of fat in breasts, neck, chest, stomach, upper back and loss of fat from legs, arms, and face.
  • You must take necessary precautions (practicing safer sex and making other life-style changes) to avoid spreading of HIV virus to others.
  • Tell your doctor if you are pregnant or planning to become pregnant.

Frequently asked questions

Nelfinavir

Q.What is nelfinavir used for?
Nelfinavir is a protease inhibitor used for the treatment for human immunodeficiency virus (HIV) infection, along with other medications (other antiretroviral agents).


Content on this page was last updated on 03 October, 2016, by Dr. Varun Gupta (MD Pharmacology)