Trexopar 15mg Injection

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Parenteral Drugs India Ltd

Composition for Trexopar 15mg Injection

iconPrescription Required
Potentiallyunsafewith
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Alcohol
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Pregnancy
55
3 ml in 1 vial
SOLD OUT

Medicine Overview of Trexopar Injection

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Uses of Trexopar Injection

Trexopar 15mg Injection is used in the treatment of blood cancer, bone cancer, non-Hodgkin lymphoma (NHL), breast cancer, lung cancer, head and neck cancer, cervical cancer, ovarian cancer and testicular cancer.
It is also used in rheumatoid arthritis, psoriasis (silvery scaly skin rash) and ectopic pregnancy at low doses.
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Side effects of Trexopar Injection

Common

Nausea, Vomiting, Loss of appetite, Dyspepsia, Abdominal pain, Increased liver enzymes, Stomatitis (Inflammation of the mouth).

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How to use Trexopar Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Trexopar Injection works

Trexopar 15mg injection is an anticancer and immunosuppressive medication. It works in cancer by slowing the growth of cancer cells by blocking building blocks that cancer cells need to grow. It also works in autoimmune disease by decreasing the activity of body's immune system and prevents the body from attacking itself.

In Depth Information on Trexopar Injection

Expert advice for Trexopar Injection

  • For autoimmune diseases, Trexopar is taken by mouth, once a week (not every day) on the same day each week. It can take 2 to 3 weeks for Trexopar to start working.
  • Notify your doctor immediately if you develop a sore throat or fever (infection), bruising or bleeding, nausea, abdominal pain or dark urine or difficulty breathing.
  • Your doctor may ask to get complete blood count (CBC), kidney function test (KFT) and liver function test (LFT) before starting treatment and thereafter also.
  • Trexopar may harm your unborn babies or cause miscarriages. You and your partner should avoid conception (becoming pregnant or fathering children) for at least three months after your treatment with Trexopar has stopped.
  • Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
  • Inform your doctor if you have ever been diagnosed with kidney or liver problems.
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Warnings
Special precautions for Trexopar 15mg Injection
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Alcohol
CAUTION
Taking Methotrxate with alcohol increases the risk of liver damage.
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Pregnancy
CAUTION
Trexopar 15mg Injection is highly unsafe to use during pregnancy.

Human and animal studies have shown significant adverse effects on the foetus. Please consult your doctor.
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Lactation
UNSAFE
Trexopar 15mg Injection is usafe to use during lactation. D
ata suggests that the drug may cause toxicity to the baby, or the mother is suffering from a condition in which breast feeding is not advisable.
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Driving
Trexopar 15mg Injection may make you feel dizzy, drowsy or a
ffect your vision. Do not drive until your vision is clear.
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Kidney
CAUTION
Trexopar 15mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Trexopar 15mg Injection may be needed. Please consult your doctor.

Regular monitoring of kidney function test is advised while you are taking this medicine.
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Liver
CAUTION
Trexopar 15mg Injection should be used with caution in patients with liver disease. Dose adjustment of Trexopar 15mg Injection may be needed. Please consult your doctor.

Use of Trexopar 15mg Injection is not recommended in patients with severe liver disease.
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Severely interacts with other drugs like
Decamycin 4mg Injection, Walacort 0.5mg Tablet, Pericort 4mg Tablet, Depo Medrol 40mg Injection

Patient Concerns

Frequently asked questions for Trexopar 15mg Injection

Frequently asked questions for Methotrexate

Trexopar is not a steroid or non-steroidal anti-inflammatory drugs (NSAIDs). It is a chemotherapy drug used in the treatment of different types of cancer and it is also a disease-modifying antirheumatic drugs (DMARD) used in the treatment of severe rheumatoid arthritis
Trexopar belongs to a class of drugs known as antimetabolites used to treat severe, uncontrolled psoriasis. Trexopar is safe if used at prescribed doses for the prescribed duration as advised by your doctor
Yes. Trexopar's chemotherapeutic effects are cell-cycle specific as it inhibits the DNA synthetic phase, i.e. it inhibits the synthesis of DNA (genetic material) of the cells. Hence in cancer treatment, it kills the cancerous cells and reduces the tumor size
Trexopar is safe if used at prescribed doses for the prescribed duration as advised by your doctor
No. Trexopar is not a narcotic drug/ biologic drug
Q. Can I take methotrexate with antibiotics (e.g. amoxicillin, Bactrim)/ ibuprofen/ prednisone/ naproxen/ aspirin/ paracetamol?
No. Methotrexate interacts with antibiotics (e.g. amoxicillin, Bactrim), ibuprofen, prednisone, naproxen, aspirin, paracetamol. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required
Always consult your doctor regarding its use if you have any symptoms of infection such as cold
Trexopar belongs to a class of drugs known as antimetabolites. It is used for the treatment of wide range of cancer and tumors. However it may increase the risk of secondary malignancies such as melanoma and other cancers
Trexopar may cause side effects such as fatigue, diarrhea, acne, mood swings, nausea, and infertility. But it has no known effect on weight gain/ weight loss
Trexopar belongs to a class of drugs known as antimetabolites. Trexopar is used for the treatment of wide range of cancers or tumors including acute leukemias (a type of blood cancer), non-Hodgkin's lymphoma (a type of cancer of immune system cells that help the body fight infections), soft-tissue (fat, muscle, nerves, fibrous tissues, blood vessels, or deep skin tissues of the body) and osteogenic sarcomas (bone cancer), and solid tumors (cancers) of the breast, lung, head and neck, bladder, cervical, ovarian, choriocarcinoma and testicular carcinoma. It is also used to treat severe, uncontrolled psoriasis (skin condition where scaly patches were formed due to fast growing cells) and rheumatoid arthritis (inflammatory disorder that typically affects the small joints in hands and feet) only if these have not responded to other frontline treatments.
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