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Advanced International Certification Course in Diabetes, Cardio-diabetes, Thyroid and Endocrine Disorders, BDS
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Last updated on:
22 Mar 2019 | 12:00 PM (IST)
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Topdep S 10 mg Tablet


Uses of Topdep S Tablet

Topdep S 10 mg Tablet is used in the treatment of depression.

Topdep S Tablet side effects

  • Low sexual desire
  • Delayed ejaculation
  • Insomnia (difficulty in sleeping)
  • Vomiting
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Nausea
  • Weight gain
  • Erectile dysfunction
  • Stomach upset
  • Restlessness

How to use Topdep S Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Topdep S 10 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Topdep S Tablet works

Topdep S 10 mg Tablet is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It works by increasing the levels of serotonin, a chemical messenger in the brain. This improves mood and physical symptoms in depression and relieves symptoms of panic and obsessive disorders.

Topdep S Tablet related warnings

Topdep S 10 mg Tablet may cause excessive drowsiness with alcohol.
Topdep S 10 mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Topdep S 10 mg Tablet is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
Topdep S 10 mg Tablet may cause side effects which could affect your ability to drive.
Topdep S 10 mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Topdep S 10 mg Tablet may be needed. Please consult your doctor.
Topdep S 10 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Topdep S 10 mg Tablet may be needed. Please consult your doctor.

What if you miss a dose of Topdep S Tablet?

If you miss a dose of Topdep S 10 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Topdep S 10 mg Tablet
Rexipra 10 Tablet
Intas Pharmaceuticals Ltd
22% costlier
21% costlier
Nexito 10 Tablet
Sun Pharmaceutical Industries Ltd
22% costlier
Feliz-S -10 Tablet
Torrent Pharmaceuticals Ltd
21% costlier
22% costlier

Expert Advice

  • It is one of the most well-tolerated antidepressant.
  • Topdep S 10 mg Tablet effectively treats a variety of mental health conditions such as depression and anxiety.
  • It can take 2-3 weeks for Topdep S 10 mg Tablet to start working.
  • It has a lower chance of causing sexual dysfunction than other similar medications.
  • Take it in the morning since it can keep you awake if taken late at night.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
  • The addiction/dependence potential of Topdep S 10 mg Tablet is very less.
  • Do not stop taking the medication suddenly without talking to your doctor.

Interaction with Drugs

Taking Topdep S with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Norma, Cizonil
Brand(s): Diabic, Glicla
Brand(s): Imirise, Imikon
Brand(s): Euroglip, Pridex MG, Glimpee
Brand(s): R Zep
Brand(s): DLX, Dutron, Dulok
Brand(s): Antep
Brand(s): Stoin, Marantin

Patient Concerns

Questions Related to Topdep S

Sir my husband has diabetic. N he feels he s not fit for physical relationship. And he s fighting unwanted n suspecting Wat should I do for this problem He s nt even ready to hear me to make him understand. He s telling I'm d reason for his blood sugar lever increment
Dr. Sanjay Bhatt
Diabetes Specialist
He is in depression, that's why his behavior is like this.he needs psychiatric consultation as the doctor can convince him more better
Till how many days can we take Feliz s 5 tablet?
Dr. Jyoti Kapoor Madan
Based on your clinical history, your doctor plans the type of medicine and it's dose and duration. For first episode of anxiety/ depression/ panic, the usual maintenance phase is 6 months of asymptomatic period, after which medicines can be gradually tapered. But treatment may need to continue longer depending on severity and frequency of episodes. To take any decision to change medication or stop them, several factors have to be taken in account for which regular follow up with your psychiatrist is important. For second opinion, seek a proper consultation with another psychiatrist and take along your previous prescriptions.
Do you have any questions related to Topdep S 10 mg Tablet?


Q. Does Topdep S cause hair loss?

There are some case reports of hair loss with the use of Topdep S. It is very infrequent and it usually stops after the discontinuation of the drug. It can be very distressing for a person, especially for the females. So a person should tell his doctor if he is having hair loss with the use of Topdep S.

Q. Can I take Topdep S with coffee?

There is usually no significant effect of taking coffee with Topdep S but a very high quantity of consumption of coffee may cause restlessness and anxiety.

Q. Why does Topdep S cause nausea?

Topdep S increases the activity of serotonin, a chemical responsible for inducing vomiting.

Q. How to manage weight gain associated with the use of Topdep S?

There are reports that suggest that the use of Topdep S can cause weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight. An important point to remember is that it is easier to prevent weight gain than to lose increased weight.

Q. Can I stop taking Topdep S when my symptoms are relieved?

No, you should continue to take Topdep S even if you feel well. If you stop Topdep S suddenly, serious withdrawal symptoms may occur. Your doctor will probably decrease your dose gradually.

Q. Can the use of Topdep S cause sleepiness?

Yes, Topdep S can make you feel sleepy. At the beginning of your treatment: do not drive, operate machinery, work at heights, or participate in potentially dangerous activities, until you know how this medicine affects you.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
  1. Stahl SM, editor. Escitalopram Oxalate. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 225-29.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 494-96.
  3. Escitalopram. Copenhagen, Denmark: H Lundbeck A/S; 2016. [Accessed 23 Jan. 2019] (online) Available from:External Link
  4. U.S. National Library of Medicine. Escitalopram Oxalate. [Accessed 25 Mar. 2019] (online) Available from:External Link
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Orchid Towers', #313, Valluvar Kottam High Road, Nungambakkam, Chennai - 600 034, Tamil Nadu, India
10 tablets in 1 strip