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Tmp 300mg Tablet

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS
Last updated on 25 Feb 2026 | 11:36 AM (IST)
Tmp 300mg Tablet is an antibiotic medicine used to treat bacterial infections in your body. It helps to kill germs (bacteria) that cause various types of infections like infections of the urinary tract and respiratory tract.
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General Information

The content is shown in English
Tmp 300mg Tablet image
Tmp 300mg Tablet image

Product introduction

Tmp 300mg Tablet should be taken in the dose and duration as advised by the doctor. You may take it with or without food. It is better to have this medicine at the same time each day to get the most benefit and you should keep on taking this medicine for as long as you are prescribed. Stopping it early may make the infection to come back and harder to treat.

Some people may develop side effects like vomiting and headache. These side effects are usually temporary and go away during treatment as your body adjusts to the medicine. Consult your doctor if these side effects bother you or do not go away.

Before starting treatment with this medicine, you should tell your doctor if you are pregnant, breastfeeding or suffering from any liver, kidney or heart problems or if you are allergic to any medicine. Your doctor may get regular blood, urine tests while you are on this medication.

Uses of Tmp Tablet

Side effects of Tmp Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Tmp
  • Itching
  • Rash
  • Phototoxicity

How to use Tmp Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tmp 300mg Tablet may be taken with or without food.

How Tmp Tablet works

Tmp 300mg Tablet is an antibiotic. It works by preventing synthesis of essential proteins required by bacteria to carry out vital functions. Thus, it stops the bacteria from growing, and prevents the infection from spreading.

Quick tips

  • Your doctor has prescribed Tmp 300mg Tablet to cure your infection and improve your symptoms.
  • Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder to treat.
  • Your doctor will ensure that you are well hydrated during treatment with this medicine. 
  • Your doctor may get regular blood, urine tests while you are on this medication.
  • Do not take Tmp 300mg Tablet if you are pregnant or breastfeeding.
  • Discontinue Tmp 300mg Tablet and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Tmp 300mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
Tmp 300mg Tablet is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Tmp 300mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
There may be a possibility of skin rash in the baby.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Tmp 300mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Tmp 300mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Tmp 300mg Tablet is not recommended in patients with severe kidney disease.
Liver

Liver

UNSAFE
Tmp 300mg Tablet is unsafe to use in patients with liver disease and should be avoided.
Use of Tmp 300mg Tablet is not recommended in patients with the severe liver disease.

Interaction with drugs

Taking Tmp with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Telmisartan (Oral Route)

Do not consume Telmisartan with Trimethoprim. If concurrent use is essential, please consult your doctor. They may monitor your potassium levels closely.
Severe

Losartan (Oral Route)

Do not consume Losartan with Trimethoprim. If concurrent use is essential, please consult your doctor. They may monitor your potassium levels closely.
Severe

Olmesartan Medoxomil (Oral Route)

Do not consume Olmesartan Medoxomil with Trimethoprim. If concurrent use is essential, please consult your doctor. They may monitor your potassium levels closely.
Severe

Ramipril (Oral Route)

Do not consume Ramipril with Trimethoprim. If concurrent use is essential, please consult your doctor. They may monitor your potassium levels closely.
Severe

Irbesartan (Oral Route)

Do not consume Irbesartan with Trimethoprim. If concurrent use is essential, please consult your doctor. They may monitor your potassium levels closely.

Frequently asked questions

Usually, Tmp 300mg Tablet starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.
Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.
No, do not stop taking Tmp 300mg Tablet and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.

Fact Box

Chemical Class

Pyrimidine Derivative

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Action Class

Sulphonamides

References

  1. Petri WA Jr. Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1468-70.
  2. Chambers HF, Deck DH. Sulfonamides, Trimethoprim, & Quinolons. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 817-19
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1406-409.
  4. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 31 Mar. 2019] (online) Available from:
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 31 Mar. 2019] (online) Available from:
  6. Trimethoprim. Alphapharm Pty Ltd.; [Accessed 13 Feb. 2026] (online). Available from:
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User feedback

Bacterial infections
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Bleeding
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Jagsonpal Pharmaceuticals Ltd
Address: T-210 J, Shahpur Jat, New Delhi - 110 049, India

Vendor Details

Country of origin: India
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