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Chlorpropamide is used as an adjunct to diet and exercise to treat type 2 diabetes.

How it works

Chlorpropamide is an oral hypoglycemic agent that belongs to a class of medications called sulphonylureas. It works by stimulating the release of insulin from the pancreas.

Common side effects

Pale red skin, Itching, Dizziness, Fall in blood sugar level, Headache, Indigestion, Skin redness, Weight loss


Expert advice

  • You should be regularly monitored for blood glucose and glycosylated hemoglobin during chlorpropamide treatment.
  • Take necessary precautions while using chlorpropamide as it may cause low blood sugar levels (symptoms: headache, hunger, sweating, confusion, irritability, dizziness, or feeling shaky). It is advisable to carry a reliable source of glucose (sugar, candy or juice) to avoid low blood sugar.
  • Caution should be exercised if you are an elderly patient (? 65 years of age) and if you have cardiovascular disease.
  • Do not drive or operate machinery as chlorpropamide may cause drowsiness, dizziness, blurred vision, or lightheadedness.
  • Do not drink alcohol while taking chlorpropamide as it may worsen the side effects.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.

Frequently asked questions


 Q. Is chlorpropamide a sulfa drug?
Yes, chlorpropamide is a sulfa drug that belongs to a group called sulphonylureas. 
Q. What is chlorpropamide used for?
Chlorpropamide is used in the treatment of type 2 diabetes.
Q. How does chlorpropamide work?
Chlorpropamide stimulates the release of insulin from pancreas which helps in lowering of blood glucose level.

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)